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Study yields insights into evolutionary dynamics between bacteria and human hosts

Researchers have discovered that humans and great apes possess a receptor on their cells that detects metabolites from bacteria commonly found in fermented foods and triggers movement of immune cells.

From PLOS ONE 28 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Weekly pharmacy visits improve drug adherence and quality of life in elderly patients with heart failure

Elderly patients with heart failure who see a pharmacist once a week are more likely to take their tablets and be active in daily life, according to late breaking results from the PHARM-CHF randomized controlled trial presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology.

26 May 2019

Biomarkers help tailor diuretic treatment for acute heart failure patients

Adrenomedullin activity predicts which acute heart failure patients are at the greatest risk of death without diuretic treatment post-discharge, according to late breaking research presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology.

26 May 2019

Experimental noninvasive tool assesses efficacy of stem cell transplantation

Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials.

23 May 2019

Scientists identify target to ‘tone down’ hyper-active immunity to influenza infection

For most people, the influenza A virus, commonly known as the flu, is cleared from the body by our own immune system.

23 May 2019

Characterizing potential therapeutic target to increase heart function after heart attack

A University of Houston College of Pharmacy researcher is characterizing a potential therapeutic target to increase heart function following a heart attack, helping alleviate the symptoms of heart failure.

23 May 2019

Cannabidiol reduces cue-induced craving and anxiety in individuals with history of heroin abuse

Cannabidiol reduced cue-induced craving and anxiety in individuals with a history of heroin abuse, suggesting a potential role for it in helping to break the cycle of addiction, according to research conducted at the Icahn School of Medicine at Mount Sinai and published May 21 in the American Journal of Psychiatry.

21 May 2019

Researchers explore link between aging fat cells and Alzheimer's

Scientists want to know whether our aging fat cells are important to the onset and progression of Alzheimer's.

21 May 2019

Inhibition of protein may prevent spread of castration-resistant prostate cancer

Researchers at Boston University School of Medicine have discovered that blocking a specific protein, may be a promising strategy to prevent the spread of castration-resistant prostate cancer.

21 May 2019

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Blood diseases such as leukemia and lymphoma are currently treated with bone marrow transplants -- a transfer of blood stem cells from a healthy person to a patient in need.

21 May 2019

Honey from strawberry trees stops cell proliferation in colon cancer lines

Spanish and Italian researchers have proven that when honey from strawberry trees, a product typical of Mediterranean areas, is added to colon cancer cells grown in the laboratory, cell proliferation is stopped.

21 May 2019

A member of light-sensitive protein family plays role in adjusting skin color

A team of Brown University researchers found that opsin 3 -- a protein closely related to rhodopsin, the protein that enables low-light vision -- has a role in adjusting the amount of pigment produced in human skin, a determinant of skin color.

18 May 2019

CHLA researcher receives $3.7 million NIH grant to study development of neural circuits

Pat Levitt, PhD, Chief Scientific Officer at Children's Hospital Los Angeles and Simms/Mann Chair in Developmental Neurogenetics, received a $3.7M grant from the National Institute of Mental Health to study development of neural circuits.

17 May 2019

Neurological Side Effects of CAR T-Cell Therapy Revealed

Researchers at Brigham and Women’s Hospital quantified the neurological symptoms associated with CAR T-cell therapy and found that 77 percent of patients receiving the treatment experienced at least one neurological side effect.

16 May 2019

Study provides insight on how two proteins help influenza A virus to fight its way to cells

Researchers have provided new insight on how two proteins help influenza A virus particles fight their way to human cells.

16 May 2019

Bladder drug can accelerate atheroclerosis in mice

A drug used in the treatment of overactive bladder can accelerate atheroclerosis in mice, researchers at Karolinska Institutet in Sweden report in a study published in the Proceedings of the National Academy of Sciences.

14 May 2019

Jefferson researcher discovers a population of bone cells that subdues cancer

In breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary disease and thought they were cancer-free.

13 May 2019

Autophagy of dendritic cells supports T-cell anticancer activity

Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell anticancer activity.

13 May 2019

Research on repetitive worm behavior may shed light on repetition in humans

Repetition can be useful if you're trying to memorize a poem, master a guitar riff, or just cultivate good habits.

13 May 2019

Receptor News and Research

Study yields insights into evolutionary dynamics between bacteria and human hosts

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Weekly pharmacy visits improve drug adherence and quality of life in elderly patients with heart failure

Biomarkers help tailor diuretic treatment for acute heart failure patients

Experimental noninvasive tool assesses efficacy of stem cell transplantation

Scientists identify target to ‘tone down’ hyper-active immunity to influenza infection

Characterizing potential therapeutic target to increase heart function after heart attack

Cannabidiol reduces cue-induced craving and anxiety in individuals with history of heroin abuse

Researchers explore link between aging fat cells and Alzheimer's

Inhibition of protein may prevent spread of castration-resistant prostate cancer

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Honey from strawberry trees stops cell proliferation in colon cancer lines

A member of light-sensitive protein family plays role in adjusting skin color

CHLA researcher receives $3.7 million NIH grant to study development of neural circuits

Neurological Side Effects of CAR T-Cell Therapy Revealed

Study provides insight on how two proteins help influenza A virus to fight its way to cells

Bladder drug can accelerate atheroclerosis in mice

Jefferson researcher discovers a population of bone cells that subdues cancer

Autophagy of dendritic cells supports T-cell anticancer activity

Research on repetitive worm behavior may shed light on repetition in humans

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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