Genetic News and Research

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Genetic cause of lupus identified

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

27 Apr 2022

Intestinal inflammation liberates chemicals that nourish the growth of E. coli in Crohn's disease

A multi-year study of the role of E. coli gut bacteria in Crohn's disease finds that intestinal inflammation liberates chemicals that nourish the bacteria's growth and promotes their ability to cause inflammation.

27 Apr 2022

Gene discovery could pave the way for new and more effective treatments for lupus

Researchers from The Australian National University have identified a gene called TLR7 that, when over-activated, is responsible for causing lupus, an autoimmune disease that can be life-threatening in severe cases.

27 Apr 2022

Cellular reprogramming can lead to better liver tissue regeneration in mice

Mammals can't typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset liver cells to more youthful states - allowing them to heal damaged tissue at a faster rate than previously observed.

27 Apr 2022

Healthy diet associated with lower diabetes risk across all levels of genetic risk

Genetic risk factors and diet quality are independently associated with type 2 diabetes; a healthy diet is linked to lower diabetes risk across all levels of genetic risk.

27 Apr 2022

New insights into the link between EMFs, calcium and Alzheimer’s disease

For almost a quarter of a century, researchers have been studying and publishing on the effect of calcium on Alzheimer's Disease. Research has led to the development of the calcium hypothesis of Alzheimer's disease, which argues that Alzheimer's is caused by excessive intracellular calcium.

26 Apr 2022

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

26 Apr 2022

Genetic variations in critical mitochondrial enzyme play a role in age-related mobility changes

Age-related changes in strength and mobility may depend on genetic variations in a critical mitochondrial enzyme, suggests a study published today in eLife.

26 Apr 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

Canine COVID-19 vaccine could prevent reverse transmission of SARS-CoV-2

The new study, published in the journal Vaccines, reports on an attempt to use the SARS-CoV-2 spike subunit protein to elicit an immune reaction.

26 Apr 2022

As vaccination coverage increases, SARS-CoV-2 genetic diversity decreases

In a recent letter to the editor published in the Journal of Infection, researchers from the Chinese PLA Center for Disease Control and Prevention observed that the genetic diversity of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could be suppressed by high coverage of vaccination.

25 Apr 2022

Common subcutaneous antibody therapy for immunodeficient patients has anti-SARS-CoV-2 antibodies

Researchers at the University of Texas Medical Branch recently confirmed the presence of neutralizing antibodies to SARS--COV-2 in a common subcutaneous antibody therapy (Hizentra) used to treat immunocompromised or immunodeficient patients, citing its protective benefits to the immunocompromised patient community.

25 Apr 2022

Drug-resistant mold found to be spreading and infecting susceptible people's lungs

A new study led by Imperial College London finds that drug-resistant mold is spreading from the environment and infecting susceptible people's lungs.

25 Apr 2022

Researchers develop new platform capable of mitochondrial DNA editing

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED.

25 Apr 2022

Recipients for the 2022 NCCN Foundation Young Investigator Awards Program announced

The National Comprehensive Cancer Network and the NCCN Foundation today announced seven recipients for the 2022 NCCN Foundation Young Investigator Awards (YIA) Program.

25 Apr 2022

MGH investigators find important regulators of urinary concentration in the kidney

Proper function of the kidney is critical for concentrating urine, regulating blood pressure, and for the tight control of electrolyte levels in the blood.

25 Apr 2022

Using AI to predict cancer from patient data without putting personal information at risk

A new way of using artificial intelligence to predict cancer from patient data without putting personal information at risk has been developed by a team including University of Leeds medical scientists.

25 Apr 2022

New study shows racial differences in breast cancer genomic profiling

A new study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has found that Black women with metastatic breast cancer were less likely to have tumors with treatable genetic variations than white and Asian women.

25 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.

25 Apr 2022

Genetic News and Research

Genetic cause of lupus identified

Intestinal inflammation liberates chemicals that nourish the growth of E. coli in Crohn's disease

Gene discovery could pave the way for new and more effective treatments for lupus

Cellular reprogramming can lead to better liver tissue regeneration in mice

Healthy diet associated with lower diabetes risk across all levels of genetic risk

New insights into the link between EMFs, calcium and Alzheimer’s disease

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Genetic variations in critical mitochondrial enzyme play a role in age-related mobility changes

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

Canine COVID-19 vaccine could prevent reverse transmission of SARS-CoV-2

As vaccination coverage increases, SARS-CoV-2 genetic diversity decreases

Common subcutaneous antibody therapy for immunodeficient patients has anti-SARS-CoV-2 antibodies

Drug-resistant mold found to be spreading and infecting susceptible people's lungs

Researchers develop new platform capable of mitochondrial DNA editing

Recipients for the 2022 NCCN Foundation Young Investigator Awards Program announced

MGH investigators find important regulators of urinary concentration in the kidney

Using AI to predict cancer from patient data without putting personal information at risk

New study shows racial differences in breast cancer genomic profiling

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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