Inflammation News and Research

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Common antioxidant enzyme catalase as COVID-19 treatment

A new paper by researchers from the USA and China and published on the preprint server bioRxiv in July 2020 discusses a new drug based on the catalase enzyme, which could play a vital part in reducing the inflammation associated with progressive and severe COVID-19 disease.

17 Jul 2020

A new strategy to combat treatment resistance in choroidal neovascularization

An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for choroidal neovascularization (CNV), an aggressive form of age-related macular degeneration, the leading cause of irreversible blindness in the elderly.

16 Jul 2020

Inflammageing may be related to worse COVID-19 outcomes in older individuals

The increased severity and mortality of SARS-CoV-2 infections in older individuals may be related to inflammageing - an age-associated phenomenon of increased general inflammation.

16 Jul 2020

CBD may help reduce cytokine storm and excessive lung inflammation in COVID-19

Cannabidiol, or CBD, may help reduce the cytokine storm and excessive lung inflammation that is killing many patients with COVID-19, researchers say.

16 Jul 2020

Prominent pharmacologist calls for new approach to treat COVID-19

A prominent Australian pharmacologist has called for a new approach to treating COVID-19 as hopes fade of finding an effective vaccine or antiviral before the end of the year.

16 Jul 2020

COVID-19 pandemic is impacting the physical activity of older adults

By now, we're all aware that COVID-19 is especially dangerous for older adults--the older you are, the higher your risk for serious illness and even death if you contract the virus.

16 Jul 2020

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Statins are a class of drugs often used to control high cholesterol levels in obesity. Now, a study published on the preprint server medRxiv* in July 2020 suggests that statins do not aggravate the risk of COVID-19 infection and may have a small beneficial effect in some cases.

16 Jul 2020

Children with MIS-C have different antibody responses than adults with COVID-19

A new study published on the preprint medRxiv in July 2020 reveals that children with the condition Multisystem Inflammatory Syndrome in Children (MIS-C) have a distinctly different pattern of antibody generation compared to adults with COVID-19 disease.

16 Jul 2020

Evidence of SARS-CoV-2 placental infection in mild COVID-19

Now, a new study published on the preprint server medRxiv* in July 2020 reveals evidence of placental infection and hypoxia, despite the lack of serious symptoms in the mother.

16 Jul 2020

Peptide-derived nanoparticle drug shows promise for treating heart attack

Researchers at the University of Illinois at Chicago have developed a new drug that prevents blood clots without causing an increased risk of bleeding, a common side effect of all antiplatelet medications currently available.

15 Jul 2020

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them.

15 Jul 2020

Study explains why fetuses and newborns are mostly spared by COVID-19

Amid the coronavirus pandemic, it has been previously suggested that the most vulnerable individuals to developing severe coronavirus disease (COVID-19) include the elderly, those with underlying health conditions, and those who have weakened immune systems.

15 Jul 2020

Buck researchers investigate ketone bodies as possible therapeutic against COVID-19

Given the disproportionate impact that COVID-19 has on older adults in terms of death and lasting disability, and the impact of common aging-related comorbidities like diabetes and cardiovascular disease, Buck Institute professor and practicing geriatrician John Newman, MD, PhD, can make a compelling argument that those infected with the SARS-CoV2 virus are suffering from an aging-related disease, no matter how old they are when they get infected.

15 Jul 2020

Hyperbaric oxygen therapy can enhance the cognitive performance of healthy older adults

The Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center, together with the Sackler School of Medicine and Sagol School of Neuroscience at Tel Aviv University, announced today that a peer-reviewed study has demonstrated for the first time that hyperbaric oxygen therapy (HBOT) can significantly enhance the cognitive performance of healthy older adults.

15 Jul 2020

Study identifies possible factors to predict severe toxicities in CAR T patients

Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In clinical trials, the cellular immunotherapy was shown to provide durable remissions for nearly 40% of large B cell lymphoma patients.

15 Jul 2020

Anti-inflammatory medication helps fight dangerous immune response in COVID-19 patients

Most patients hospitalized with COVID-19 (coronavirus) pneumonia experienced improvement after receiving a Food and Drug Administration-approved drug normally given for rheumatoid arthritis, according to an observational study at Cedars-Sinai.

15 Jul 2020

EMAS study investigates factors associated with diagnostic delay in axial spondyloarthritis

Axial spondyloarthritis (axSpA) is a chronic systemic rheumatoid-inflammatory disease associated with inflammation of the spine. "The affected patients often have been experiencing spinal pain since early adulthood",

15 Jul 2020

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

10x Genomics strengthened the research toolkit of scientists around the globe today with the launch of its Chromium Single Cell Immune Profiling v2 product.

15 Jul 2020

Certain antibodies may cause the dangerous part of COVID-19 disease

A new study out of the Netherlands and published on the preprint server bioRxiv* in July 2020 discusses the commonly observed phenomenon of COVID-19 progression at 1-2 weeks from the onset of the earliest symptoms. This is ascribed to the overactivation of the inflammatory signaling cascade triggered by a hyperactive adaptive immune reaction, commonly called the cytokine storm.

15 Jul 2020

Combining Western-style high-fat diet with antibiotic use increases risk of pre-IBD

UC Davis researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre-inflammatory bowel disease (pre-IBD).

14 Jul 2020

Inflammation News and Research

Common antioxidant enzyme catalase as COVID-19 treatment

A new strategy to combat treatment resistance in choroidal neovascularization

Inflammageing may be related to worse COVID-19 outcomes in older individuals

CBD may help reduce cytokine storm and excessive lung inflammation in COVID-19

Prominent pharmacologist calls for new approach to treat COVID-19

COVID-19 pandemic is impacting the physical activity of older adults

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Children with MIS-C have different antibody responses than adults with COVID-19

Evidence of SARS-CoV-2 placental infection in mild COVID-19

Peptide-derived nanoparticle drug shows promise for treating heart attack

New immune profiles could help predict disease trajectory in severe COVID-19 patients

Study explains why fetuses and newborns are mostly spared by COVID-19

Buck researchers investigate ketone bodies as possible therapeutic against COVID-19

Hyperbaric oxygen therapy can enhance the cognitive performance of healthy older adults

Study identifies possible factors to predict severe toxicities in CAR T patients

Anti-inflammatory medication helps fight dangerous immune response in COVID-19 patients

EMAS study investigates factors associated with diagnostic delay in axial spondyloarthritis

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

Certain antibodies may cause the dangerous part of COVID-19 disease

Combining Western-style high-fat diet with antibiotic use increases risk of pre-IBD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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