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SLU researchers reveal how to turn off neuropathic pain in a laboratory setting

Facing an urgent need for safer and more effective therapies for those suffering from debilitating pain in the midst of an opioid crisis, Saint Louis University researchers are on a mission to find a non-narcotic off-switch for pain.

10 May 2019

Study provides first evidence of crosstalk between the heart and fat cells

Like sending a letter through the mail or a text over a cellular network, the heart can generate messages that travel long distances through the body.

10 May 2019

HSS researchers provide better understanding of the cellular mechanisms driving rheumatoid arthritis

Newly identified subsets of cell types present in joint tissue in people with rheumatoid arthritis and how they interact may explain why only some people respond to existing medications, according to two studies by co-senior author Laura Donlin, PhD, Co-Director of the Derfner Foundation Precision Medicine Laboratory at Hospital for Special Surgery and collaborating colleagues.

10 May 2019

Genomics study reveals five genes linked to treatment resistance in prostate cancer

A new genomics study has found that men are three times more likely to die from prostate cancer if they possess mutations the retinoblastoma 1 (RB1) gene.

8 May 2019

Researchers unravel the biology of how obesity promotes triple-negative breast cancer

Smoking has long been the biggest cause of cancer in the United States, but obesity, now the second leading cause, has been gaining ground.

7 May 2019

The endocannabinoid system and skin conditions

a significant amount of research over the past 20 years has demonstrated that the endocannabinoid system plays a vital role in skin homeostasis, and therefore skin conditions too.

7 May 2019

KAIST research team finds cause of sepsis-induced lung injury

A KAIST research team succeeded in visualizing pulmonary microcirculation and circulating cells in vivo with a custom-built 3D intravital lung microscopic imaging system.

7 May 2019

Researchers develop new molecule that binds to the cerebrovascular system

Brazilian and US researchers have developed a molecule called FRW that, in tests with mice, proved capable of binding to blood vessels in the brain but not in other organs when injected into the bloodstream.

7 May 2019

Researchers develop a new approach to targeting tumors and metastases

The spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is the main cause of cancer deaths worldwide.

7 May 2019

CU Anschutz researchers identify new immunodeficiency disease

A new immunodeficiency disease caused by a novel genetic mutation has been identified by researchers at the University of Colorado Anschutz Medical Campus providing unique insights into cell biology.

6 May 2019

NIH-funded trial demonstrates safety of potential treatment in lung transplant patients

A new study, presented today at the American Association for Thoracic Surgery's 99th Annual Meeting, shows that a potential treatment for ischemia- reperfusion injury is safe for humans.

6 May 2019

Scientists discover biological barrier that keeps cancer at bay

Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function.

6 May 2019

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Glioblastoma is an incurable type of brain tumor that is frequently associated with mutations in the epidermal growth factor receptor.

3 May 2019

New method could lead to more personalized treatment of advanced prostate cancer

Researchers at Karolinska Institutet in Sweden have identified blood-based biomarkers that may determine which patients will benefit from continued hormonal therapy for advanced prostate cancer.

3 May 2019

Targeting antidiuretic hormone vasopressin shows promise for autism

Autism is a complex neurodevelopmental disorder with no known drug treatment up until now. Researchers have finally found tweaking certain hormones could help patients with autism. There were two independent clinical trials including children and adults with autism that altered the effects of the hormone vasopressin and to assess the effects on social functioning.

2 May 2019