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Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

A newly published analysis in the Journal of the American College of Cardiology1 of hospitalized patients with both a severe type of heart attack called STEMI (ST-elevation myocardial infarction) and coronavirus disease-19 (COVID-19) infection compares clinical outcomes for these patients during the first and second years of the COVID-19 pandemic.

3 May 2022

Educational attainment associated with better health in Black women

One of the best things Black women can do for their health may be to get a college education, according to results of a national analysis.

3 May 2022

Study uncovers blood clotting and immune protein pathways impacted in children with severe COVID-19

Researchers have discovered the blood clotting and immune protein pathways that are activated in severe cases of COVID-19 in children, paving the way for earlier diagnosis and more targeted treatments.

3 May 2022

Novel genetic mapping study traces links between DNA variations and blood proteins

A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links between DNA variations and thousands of blood proteins in two large and distinct populations. The results should help researchers better understand the molecular causes of diseases and identify proteins that could be targeted to treat these diseases.

3 May 2022

$6 million grant to fund research investigating the role of immune system in heart failure

A new grant for researchers at Washington University School of Medicine in St. Louis will fund research investigating the role of the immune system in heart failure. Finding ways to harness beneficial immune cells could lead to new therapies that encourage the heart to heal after injuries.

2 May 2022

A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

When a patient in the pediatric intensive care unit (PICU) develops a fever, physicians often routinely order a blood culture to identify the cause, particularly if they have reason to worry about sepsis, a life-threatening condition that occurs when chemicals released by immune system cells in the bloodstream to fight an infection trigger inflammation and shock throughout the body.

2 May 2022

Exploring changes in non-COVID-19 hospitalization rates before and during COVID-19

Researchers assessed the trends in non-COVID-19 hospitalizations before and during the COVID-19 pandemic in the United States between 2017 and 2021.

2 May 2022

Obesity progression may contribute to the economic burden of the disease, studies suggest

Obesity is known to approximately double healthcare costs in the US compared to those with a healthy weight.

2 May 2022

British children's sugar intake exceeds current public health recommendations

A new study, being presented at this year's European Congress on Obesity (ECO) in Maastricht, Netherlands (4-7 May), suggests that children in the UK start consuming free sugars (those added to foods and drinks and those occurring naturally in fruit juices, honey and syrups) at a very young age, and that many toddlers' sugar intake exceeds the maximum recommended amount for children aged 4 and older.

2 May 2022

How diet and nutrition impacts lifespan

In a recent study published in the journal Cell, researchers analyzed the association between human longevity to growth and metabolic pathways.

1 May 2022

New cardiac defibrillator implanted under the skin greatly reduces patient complications

High-risk patients who need defibrillators to prevent cardiac arrest can experience fewer complications with a type of device implanted under the skin, a Canadian study has found.

30 Apr 2022

Researchers test a method for delivering genetic material into the body to repair damaged heart muscle

A method for delivering genetic material to the body is being tested as a way to repair damaged heart muscle after a heart attack.

30 Apr 2022

Exploring happy hypoxia in COVID-19 patients

In a new study, researchers reported that silent hypoxia was not unique to COVID-19.

29 Apr 2022

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

In a recent randomized clinical trial of hospitalized patients with COVID-19 and cardio-metabolic risk factors, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin did not significantly reduce patients' risk of organ failure, kidney problems, or death compared with placebo, although numerically fewer participants treated with dapagliflozin experienced these outcomes. The findings are published in CJASN.

29 Apr 2022

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body.

29 Apr 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

All humans carry genetic variations in their DNA, called Single Nucleotide Polymorphisms (SNPs) that can underlie susceptibility to diseases such as diabetes and cancer.

28 Apr 2022

NIH awards $10.9 million COBRE grant to support Nemours Children's 'well beyond medicine' strategy

The National Institutes of Health (NIH) recently awarded a Phase 1, 5-year $10.9 million Center of Biomedical Research Excellence (COBRE) award, entitled Research Expanding Access to Child Health (REACH) Center to Anne Kazak, PhD, Enterprise Director, and Melissa Alderfer, PhD, Director of the Center for Healthcare and Delivery Science (CHDS) at Nemours Children's Health.

28 Apr 2022

AI system can enhance images of mouse brain cells in action

Johns Hopkins biomedical engineers have developed an artificial intelligence (AI) training strategy to capture images of mouse brain cells in action.

28 Apr 2022

Heart News and Research

Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

Educational attainment associated with better health in Black women

Study uncovers blood clotting and immune protein pathways impacted in children with severe COVID-19

Novel genetic mapping study traces links between DNA variations and blood proteins

$6 million grant to fund research investigating the role of immune system in heart failure

A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

Exploring changes in non-COVID-19 hospitalization rates before and during COVID-19

Obesity progression may contribute to the economic burden of the disease, studies suggest

British children's sugar intake exceeds current public health recommendations

How diet and nutrition impacts lifespan

New cardiac defibrillator implanted under the skin greatly reduces patient complications

Researchers test a method for delivering genetic material into the body to repair damaged heart muscle

Exploring happy hypoxia in COVID-19 patients

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

NIH awards $10.9 million COBRE grant to support Nemours Children's 'well beyond medicine' strategy

AI system can enhance images of mouse brain cells in action

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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