Clinical Trial News and Research

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Study provides more insight into effects of DBS in treatment of Alzheimer's disease

New findings published today by a team of researchers led by Dr. Andres Lozano at the Krembil Neuroscience Centre of Toronto Western Hospital have provided further insight into the effects of Deep Brain Stimulation (DBS) in the treatment of Alzheimer's disease.

20 Jul 2016

Anti-HIV medications provide durable protection against heterosexual transmission, study finds

Anti-HIV medications suppress the viral load of people living with HIV and provide durable protection against heterosexual transmission a study led by the University of North Carolina at Chapel Hill found.

19 Jul 2016

Maternal antiretroviral treatment eliminates HIV transmission to infants during breastfeeding

For HIV-infected mothers whose immune system is in good health, taking a three-drug antiretroviral regimen during breastfeeding essentially eliminates HIV transmission by breast milk to their infants, according to results from a large clinical trial conducted in sub-Saharan Africa and India.

19 Jul 2016

NorthShore launches first clinical trial to examine GRS test for cancer risk assessment

Researchers at NorthShore University HealthSystem have launched the first clinical trial to investigate a genetic risk score (GRS) test to predict the risk of breast, prostate and colorectal cancer in the primary care setting.

19 Jul 2016

HOPE study seeks to understand safety of vaginal ring in protecting women against HIV

Women who took part in ASPIRE, a trial that found a vaginal ring containing an antiretroviral (ARV) drug called dapivirine was safe and helped protect against HIV, will soon be offered the opportunity to use the ring as part of a new study called HOPE.

19 Jul 2016

Soligenix announces encouraging preliminary results of heat stable Ebola vaccine

A biopharmaceutical company collaborating with Hawai'i scientists on an Ebola vaccine announced encouraging news about its vaccine today.

19 Jul 2016

Postmenopausal estrogen supplement may not affect memory of healthy women

Contrary to popular belief, taking estrogen after menopause may not affect the memory and thinking abilities of healthy women no matter when the treatment is started.

19 Jul 2016

SLU researchers study investigational vaccine for yellow fever

Saint Louis University's Center for Vaccine Development is studying an investigational vaccine for yellow fever, a potentially deadly disease that is spread by the same mosquito that transmits Zika virus.

19 Jul 2016

Tecnis Symfony Extended Range of Vision IOL approved for cataract patients

The U.S. Food and Drug Administration today approved the first intraocular lens (IOL) that provides cataract patients with an extended depth-of-focus, which helps improve their sharpness of vision (visual acuity) at near, intermediate and far distances.

18 Jul 2016

Study finds sex differences in smoking cessation with medications

A new study led by Assistant Medical Professor Philip Smith of The City College of New York's Sophie Davis Biomedical Education/CUNY School of Medicine, and conducted in collaboration with researchers at Yale University and Yeshiva University, found important differences between women and men in their ability to quit smoking when taking medications commonly prescribed to help smokers quit.

17 Jul 2016

Interim results from clinical trial demonstrate safety of cell-based therapy for retinitis pigmentosa

Regenerative medicine company jCyte and the Sue & Bill Gross Stem Cell Research Center at the University of California, Irvine report that their investigational therapy for retinitis pigmentosa (RP) has demonstrated a favorable safety and tolerability profile in an ongoing Phase I/II clinical trial.

14 Jul 2016

PinnacleHealth delivers ABSORB BVS device to first patient after FDA approval

The same PinnacleHealth team that participated in a three-year clinical trial designed to evaluate potential benefits of a first-of-its-kind drug eluting ABSORB Bioresorbable Vascular Scaffold (BVS), today announced it deployed the device for the first time after FDA approval for commercial use.

14 Jul 2016

Clinical study examines new treatment option for aortic stenosis patients with larger valve structure

A clinical trial exploring a new minimally invasive treatment option for some patients with severe aortic stenosis recently launched at Baylor Jack and Jane Hamilton Heart and Vascular Hospital.

14 Jul 2016

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Cancer remains a leading cause of death worldwide, and the global cancer burden is expected to increase by 70 percent over the next two decades.

14 Jul 2016

Study finds evidence that PD-1 antibody may benefit men with metastatic prostate cancer

Restoring tumor-specific immunity is a treatment strategy that works well in melanoma and lung cancer patients. Now a new study out of the OHSU Knight Cancer Institute is reviving hope that the approach also may help men with life-threatening prostate cancer.

14 Jul 2016

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

The Wistar Institute is pleased to announce that the National Institutes of Health has awarded a nearly $23 million Martin Delaney Collaboratories for HIV Cure Research grant to the BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy, a consortium of top HIV researchers led by co-principal investigators Luis J. Montaner, D.V.M., D.Phil., director of the HIV-1 Immunopathogenesis Laboratory at The Wistar Institute Vaccine Center, and James L. Riley, Ph.D., research associate professor at the Perelman School of Medicine at the University of Pennsylvania.

13 Jul 2016

Community-level ART coverage, male circumcision linked to decline in new male HIV infections in Uganda

Increasing the number of men who undergo circumcision and increasing the rates at which women with HIV are given antiretroviral therapy (ART) were associated with significant declines in the number of new male HIV infections in rural Ugandan communities, new Johns Hopkins Bloomberg School of Health research suggests.

13 Jul 2016

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.

12 Jul 2016

New eye test could help detect glaucoma earlier than current techniques

UNSW Australia scientists have developed a testing protocol that identifies the blinding eye disease glaucoma four years earlier than current techniques.

12 Jul 2016

Bariatric surgery becomes safer in accredited surgical centers, research shows

Patients who have weight-loss operations at nonaccredited bariatric surgical facilities in the United States are up to 1.4 times likelier to experience serious complications and more than twice as likely to die after the operation compared with patients who undergo these procedures at accredited bariatric surgical centers, researchers conclude.

12 Jul 2016

Clinical Trial News and Research

Study provides more insight into effects of DBS in treatment of Alzheimer's disease

Anti-HIV medications provide durable protection against heterosexual transmission, study finds

Maternal antiretroviral treatment eliminates HIV transmission to infants during breastfeeding

NorthShore launches first clinical trial to examine GRS test for cancer risk assessment

HOPE study seeks to understand safety of vaginal ring in protecting women against HIV

Soligenix announces encouraging preliminary results of heat stable Ebola vaccine

Postmenopausal estrogen supplement may not affect memory of healthy women

SLU researchers study investigational vaccine for yellow fever

Tecnis Symfony Extended Range of Vision IOL approved for cataract patients

Study finds sex differences in smoking cessation with medications

Interim results from clinical trial demonstrate safety of cell-based therapy for retinitis pigmentosa

PinnacleHealth delivers ABSORB BVS device to first patient after FDA approval

Clinical study examines new treatment option for aortic stenosis patients with larger valve structure

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Study finds evidence that PD-1 antibody may benefit men with metastatic prostate cancer

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

Community-level ART coverage, male circumcision linked to decline in new male HIV infections in Uganda

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

New eye test could help detect glaucoma earlier than current techniques

Bariatric surgery becomes safer in accredited surgical centers, research shows

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