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Cognitive changes following major surgery not linked with changes in Alzheimer's-related biomarkers

Cognitive changes following non-neurologic and non-cardiac surgery were not associated with changes in Alzheimer's disease-related biomarkers in older patients, according to a study led by a team at Duke University School of Medicine.

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

A recent study showed that the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant is a chimera of two earlier PANGO lineages of SARS-CoV-2.

2 Feb 2022

Rolling brain wave patterns can provide clue to understanding sleep, anesthesia, and attention

While sleeping, the entire brain rolls through long, slow waves of electrical activity, like waves on a calm ocean. Researchers call that state of consciousness "slow wave sleep".

2 Feb 2022

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Ulcerative colitis, a subtype of inflammatory bowel disease, is a chronic ailment of the colon affecting nearly one million individuals in the United States. It is thought to be linked to disruptions in the gut microbiome - the bacteria and other microbes that live inside us - but no existing treatments actually target these microorganisms.

2 Feb 2022

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

A large multinational group of researchers has shown how the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gained exceptional immune evasion properties but also a much lower propensity to enter cells such as those in lung alveoli, resulting in its reduced pathogenicity. Their paper is currently released as an unedited version of the manuscript prior to publication in the journal Nature.

1 Feb 2022

Individual dosing of preparatory drug makes stem cell transplants safer for children

Individual dosing of a drug used to prepare children for stem cell transplantation makes this treatment safer. That's according to new research by scientists from the Princess Máxima Center and the Wilhelmina Children's Hospital.

1 Feb 2022

Researchers generate a complex kidney-like 3D tissue in the lab

A research team based in Kumamoto University (Japan) has created complex 3D kidney tissue in the lab solely from cultured mouse embryonic stem (ES) cells.

1 Feb 2022

Researchers discover why patients suffering with hypertension also have diabetes

The long-standing enigma of why so many patients suffering with high blood pressure (known as hypertension) also have diabetes (high blood sugar) has finally been cracked by an international team led by the universities of Bristol, UK, and Auckland, New Zealand.

1 Feb 2022

Stigma around birth defects still plagues people in Africa

Cynthia Solomon, a 45-year-old businesswoman in Nigeria, started having issues in her matrimonial home when she gave birth to two children with Down syndrome.

1 Feb 2022

Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

A randomized controlled trial assesses the efficacy and safety of high-dose convalescent plasma in the treatment of severe COVID-19.

1 Feb 2022

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according to findings published in Proceedings of the National Academy of Sciences.

1 Feb 2022

Mutational analysis of SARS-CoV-2 main protease

A new study discussed the findings of a comprehensive mutational analysis of the main protease (Mpro) of SARS-CoV-2.

1 Feb 2022

Researchers develop new technique to open the blood-brain barrier in lab animals

University of Maryland School of Medicine researchers developed a technique in laboratory animals to consistently and reproducibly open the blood-brain barrier.

31 Jan 2022

Researchers visualize protein machinery of respiration for the first time

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

31 Jan 2022

New approach to make RNA vaccines easier to swallow

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

31 Jan 2022

Combined strategy suppresses the growth of deadly brain tumor

Short bursts of radiation therapy dramatically enhanced the efficiency of targeting glioblastomas with natural nanoparticle-based immunotherapy, thus suppressing growth of the deadly tumor, inducing anti-tumor immunity and prolonging survival in animal models, a research team at Massachusetts General Hospital has discovered.

31 Jan 2022

Drugs News and Research

Cognitive changes following major surgery not linked with changes in Alzheimer's-related biomarkers

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

Rolling brain wave patterns can provide clue to understanding sleep, anesthesia, and attention

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

Individual dosing of preparatory drug makes stem cell transplants safer for children

Researchers generate a complex kidney-like 3D tissue in the lab

Researchers discover why patients suffering with hypertension also have diabetes

Stigma around birth defects still plagues people in Africa

Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Mutational analysis of SARS-CoV-2 main protease

Researchers develop new technique to open the blood-brain barrier in lab animals

Researchers visualize protein machinery of respiration for the first time

New approach to make RNA vaccines easier to swallow

Combined strategy suppresses the growth of deadly brain tumor

MCL1 regulates neuronal autophagy, cell survival in Alzheimer's disease

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Study identifies drugs that could help combat mortality in patients with COVID-19

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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