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Researchers discover how gene commonly linked to obesity contributes to weight gain

Researchers have discovered how a gene commonly linked to obesity—FTO—contributes to weight gain. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells.

23 May 2014

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.

23 May 2014

Researchers resolve long-standing mystery of enzyme's role in cell survival

St. Jude Children's Research Hospital solves mystery of enzyme's role in cell survival, offering clues of how immune system fights infection and possible strategies to treat problems ranging from heart attack to cancer.

23 May 2014

New discovery cracks code of metabolic pathway that allows certain cancerous tumors to thrive

In a breakthrough discovery at the Children's Medical Center Research Institute at UT Southwestern (CRI), a research team led by Ralph DeBerardinis, M.D., Ph.D., has taken a significant step in cracking the code of an atypical metabolic pathway that allows certain cancerous tumors to thrive, providing a possible roadmap for defeating such cancers.

23 May 2014

NCCN receives $2M grant to evaluate effectiveness of volasertib in treatment of hematologic malignancies

The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) has been awarded a $2-million grant from Boehringer Ingelheim Pharmaceuticals, Inc.

23 May 2014

TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

Innovative treatments for heart failure are lacking, leaving the nearly six million Americans who suffer from the condition with little hope for a cure.

23 May 2014

UNC researchers find new enzyme target for treating chronic pain

Researchers at the UNC School of Medicine have found a new target for treating chronic pain: an enzyme called PIP5K1C.

22 May 2014

Researchers identify existing drugs that could be "repurposed" to fight MERS-CoV

A team led by a University of Maryland School of Medicine (UM SOM) researcher, working as a grantee from the National Institutes of Health (NIH), has identified a number of existing drugs that could be "repurposed" to fight outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus (SARS-CoV).

22 May 2014

New "18F radiotracers" to detect and track certain diseases in patients

Radioactivity is usually associated with nuclear fallout or comic-book spider bites, but in very small amounts it can be a useful tool for diagnosing diseases.

22 May 2014

New laser method provides a better understanding on how genes are controlled, regulated

Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell.

21 May 2014

Mayo Clinic study provides key insights into aggressive form of pancreatic cancer

Mayo Clinic researchers have discovered an enzyme they say is tightly linked to how aggressive pancreatic cancer will be in a patient.

21 May 2014

Research provides key insights into most aggressive form of pancreatic cancer

Mayo Clinic researchers have discovered an enzyme they say is tightly linked to how aggressive pancreatic cancer will be in a patient.

21 May 2014

Sanofi presents Phase II trial results for investigational vaccine for prevention of CDI

Sanofi Pasteur, the vaccines division of Sanofi, presented Phase II (H-030-012) trial results for an investigational vaccine for the prevention of Clostridium difficile infection at the 114th General Meeting of the American Society for Microbiology.

20 May 2014

Existing pharmaceutical drugs may offer effective therapies against MERS

A series of research articles published ahead of print in the journal Antimicrobial Agents and Chemotherapy have identified a number of existing pharmaceutical drugs and compounds under development that may offer effective therapies against Middle East Respiratory Syndrome (MERS).

20 May 2014

Three scientists selected to receive NIDA's 2014 Avant-Garde Award for HIV/AIDS Research

With proposals ranging from enhancing the immune system's ability to fight HIV infection to improving long-term immune health in HIV-infected drug users, three scientists have been chosen to receive the 2014 Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse, part of the National Institutes of Health.

19 May 2014

Convenient new treatment option for rheumatoid arthritis sufferers offers patient freedom and control of disease

A new subcutaneous formulation of RoActemra® (tocilizumab) has today been launched providing thousands of UK rheumatoid arthritis (RA) patients with a potentially life-changing treatment option.1

19 May 2014

PARADIGM-HF trial of LCZ696 for chronic heart failure stopped early for benefit

The PARADIGM-HF trial has been stopped early for a benefit to patients that was overwhelmingly statistically significant.

19 May 2014

MetLife announces recipients of 2014 MetLife Foundation Awards for Medical Research

MetLife Foundation today announced the recipients of the 2014 MetLife Foundation Awards for Medical Research.

16 May 2014

OxThera granted new patents for treatment of hyperoxaluria

OxThera AB announced today that it has been granted two new US patents and one new Australian patent during the last year.

15 May 2014

SapC-DOPS technology: New way to image glioblastoma multiforme tumors

Just because you can't see something doesn't mean it's not there. Brain tumors are an extremely serious example of this and are not only difficult to treat-both adult and pediatric patients have a five-year survival rate of only 30 percent-but also have even been difficult to image, which could provide important information for deciding next steps in the treatment process.

15 May 2014

Enzyme News and Research

Researchers discover how gene commonly linked to obesity contributes to weight gain

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers resolve long-standing mystery of enzyme's role in cell survival

New discovery cracks code of metabolic pathway that allows certain cancerous tumors to thrive

NCCN receives $2M grant to evaluate effectiveness of volasertib in treatment of hematologic malignancies

TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

UNC researchers find new enzyme target for treating chronic pain

Researchers identify existing drugs that could be "repurposed" to fight MERS-CoV

New "18F radiotracers" to detect and track certain diseases in patients

New laser method provides a better understanding on how genes are controlled, regulated

Mayo Clinic study provides key insights into aggressive form of pancreatic cancer

Research provides key insights into most aggressive form of pancreatic cancer

Sanofi presents Phase II trial results for investigational vaccine for prevention of CDI

Existing pharmaceutical drugs may offer effective therapies against MERS

Three scientists selected to receive NIDA's 2014 Avant-Garde Award for HIV/AIDS Research

Convenient new treatment option for rheumatoid arthritis sufferers offers patient freedom and control of disease

PARADIGM-HF trial of LCZ696 for chronic heart failure stopped early for benefit

MetLife announces recipients of 2014 MetLife Foundation Awards for Medical Research

OxThera granted new patents for treatment of hyperoxaluria

SapC-DOPS technology: New way to image glioblastoma multiforme tumors

Understanding the DNA Damage Response in Innate Immunity eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo