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Einstein Aging Study secures $32 million NIH grant to help address the rising tide of Alzheimer's disease

To help address the rising tide of Alzheimer's disease nationwide, researchers at Albert Einstein College of Medicine in collaboration with faculty at Pennsylvania State University and other institutions, have received a five-year, $32 million grant from the National Institutes of Health to support the ongoing Einstein Aging Study, which focuses on both normal aging and the special challenges of Alzheimer's disease, and other dementias. EAS was established at Einstein in 1980 and has been continuously funded by the NIH.

20 Apr 2022

Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils - fibrous, ropelike structures formed by closely linked protein molecules - are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022

New point-of-care COVID-19 test can differentiate alpha variant from earlier SARS-CoV-2 strains

A point-of-care COVID-19 test developed by researchers at the University of Illinois Urbana-Champaign can now detect and differentiate the alpha variant of the SARS-CoV-2 virus from earlier strains in saliva samples.

20 Apr 2022

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

20 Apr 2022

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Alzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities.

19 Apr 2022

Lifelong excess weight almost doubles the risk of developing womb cancer, shows study

New research shows that lifelong excess weight almost doubles a woman's risk of developing womb cancer, according to a Cancer Research UK-funded study published today in BMC Medicine.

19 Apr 2022

Researchers reveal possible way to treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

19 Apr 2022

Mount Sinai wins $500,000 grant to support continued innovation in pancreatic cancer treatment

The Canopy Cancer Collective, a national nonprofit organization that strives to fuel better treatments and outcomes for pancreatic cancer patients, has awarded The Tisch Cancer Institute at Mount Sinai a $500,000 grant to support continued innovation in its multidisciplinary treatment of pancreatic cancer.

19 Apr 2022

Scientists identify a way to reverse drug resistance by rewiring the inner workings of leukemia cells

Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells.

19 Apr 2022

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

19 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

Small genetic differences can affect the ability to utilize energy of various nutrients, study finds

Carbohydrates, proteins and fats are essential nutrients to all animals. Yet dietary variation between species, populations and individuals can vary dramatically.

19 Apr 2022

Why cheap, older drugs that might treat covid never get out of the lab

In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the covid ward at Yale New Haven Hospital, joining an army of health care workers who struggled to treat the deadly viral disease.

19 Apr 2022

Better understanding of hydrocephalus could lead to improved treatments

Hydrocephalus, or "water on the brain," occurs when the cerebral ventricles - four interconnected cavities of the brain that are filled with cerebrospinal fluid - become enlarged, but its cause is unknown in many cases.

18 Apr 2022

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.

18 Apr 2022

Genetic News and Research

Einstein Aging Study secures $32 million NIH grant to help address the rising tide of Alzheimer's disease

Little-known protein found to play a role in common neurodegenerative disorder

New point-of-care COVID-19 test can differentiate alpha variant from earlier SARS-CoV-2 strains

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Lifelong excess weight almost doubles the risk of developing womb cancer, shows study

Researchers reveal possible way to treat newborns with rare genetic lung condition

Mount Sinai wins $500,000 grant to support continued innovation in pancreatic cancer treatment

Scientists identify a way to reverse drug resistance by rewiring the inner workings of leukemia cells

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

Using customized 'mini-antibodies' to mitigate chronic inflammation

Small genetic differences can affect the ability to utilize energy of various nutrients, study finds

Why cheap, older drugs that might treat covid never get out of the lab

Better understanding of hydrocephalus could lead to improved treatments

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

Researchers develop and validate polygenic risk scores for six common diseases

Research shines light on the effects of genomic variation on gut microbiome function

Two strains of TB bacterium attack the lungs in completely different fashion, study finds

Monoclonal antibodies from COVID-19 convalescent donors target conserved site

Scientists investigate how gut bacteria directly control the activity of specific neurons

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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