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Safinamide significantly improved motor function in patients with advanced Parkinson's disease

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, and its partner Newron Pharmaceuticals SpA has announced that the first Phase III trial of investigational agent safinamide as adjunctive therapy to levodopa (study 016) met its primary endpoint by increasing daily "ON" time in mid- to late-stage Parkinson's disease patients with motor fluctuations by 1.3 hours.

5 Feb 2009

FDA grants priority review of Cinryze C1 inhibitor as treatment for acute attacks of hereditary angioedema

ViroPharma Incorporated has announced that the U.S. Food and Drug Administration (FDA) has granted priority review for Cinryze C1 Inhibitor (human) as a treatment for acute attacks of Hereditary Angioedema (HAE).

5 Feb 2009

Infliximab after intestinal resective surgery may help prevent post-op Crohn's disease recurrence

The administration of infliximab after intestinal resective surgery was found to be effective at preventing endoscopic and histological recurrence of Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

2 Feb 2009

Study looks at acupuncture for pain

The pain relieving effects of acupuncture compared with placebo are small and seem to lack clinical relevance, according to a study published on bmj.com.

29 Jan 2009

New bone cement may prevent amputations

Old technologies, bone cement and a well known antibiotic, may effectively fight an emerging infection in soldiers with compound bone fractures, according to a study published online in the Journal of Orthopedic Research.

29 Jan 2009

Study of cannabinoid medicine for pain found patients got 'high,' but effects not related to pain relief

Researchers at Brigham and Women's Hospital found that patients taking cannabinoid medicines for pain may be getting "high," but these effects were unrelated to relief from their pain symptoms. Results of their study, one of the first to examine the addictive potential of this class of pain medicine, were presented today at the American Academy of Pain Medicine's 25th Annual Meeting.

29 Jan 2009

Early treatment with rasagiline (Azilect) for Parkinson's best

There is hope that the drug rasagiline can do what no other medication for Parkinson's disease now does -- slow the progression of a devastating degenerative brain disease that eventually robs people of their ability to move and function.

27 Jan 2009

Inhaled corticosteroids reduces severity of asthma attacks in preschoolers

The largest study of its kind on preschoolers has demonstrated that preventive treatment with high doses of inhaled corticosteroids is effective in reducing the severity and duration of asthma attacks triggered by colds.

23 Jan 2009

Can cognitive behavioural therapy help defeat depression?

The effectiveness of cognitive behavioural therapy (CBT) for the treatment of depression will be examined by researchers at the University of Bristol as part of the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme.

22 Jan 2009

Oral steroids ineffective treatment for wheezing in children

A new study from Barts and The London School of Medicine and Dentistry has found that a common treatment for wheezing in preschool children is no more effective than a placebo.

21 Jan 2009

Anxious seniors may benefit from SSRIs

Many older adults worry - a lot. Almost one in 10 Americans over age 60 suffer from an anxiety disorder that causes them to worry excessively about normal things - like health, finances, disability and family.

21 Jan 2009

Cream containing tretinoin associated with death in clinical trial, but relationship does not appear causal

Patients using a cream containing tretinoin, a retinoid commonly used to treat acne and other conditions, appeared more likely to die than those using a placebo in a clinical trial that was halted early as a result, according to a report in the January issue of Archives of Dermatology.

19 Jan 2009

Savella - Fibromyalgia treatment approved by FDA

Forest Laboratories, Inc. and Cypress Bioscience, Inc. have announced that Savella (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor, was approved by the U.S. Food and Drug Administration (FDA) for the management of fibromyalgia.

19 Jan 2009

Depressed adolescents not harmed by being part of placebo group in clinical trial

In a national clinical trial, adolescents with moderate to severe depression first given a placebo treatment and then an antidepressant medication alone or in combination with therapy responded just as well over the long term as participants who received active treatment throughout the study, UT Southwestern Medical Center researchers report.

19 Jan 2009

Probiotics prevent IgE-associated allergy until age 5 in cesarean-delivered children but not in total cohort

According to a recent study from the University and the University Central Hospital of Helsinki, Finland, no allergy-preventive effect is extended to age 5 years by perinatal supplementation with probiotics in babies at risk for developing allergies; protection is conferred only to Cesarean section babies.

15 Jan 2009

Algeta completes phase II trial with Alpharadin for treating bone metastases in advanced prostate cancer

Algeta ASA has announced that with the results of the BC1-04 study reported today it has completed its comprehensive phase II clinical program evaluating Alpharadin (radium-223) as a new treatment for bone metastases in patients with hormone-refractory prostate cancer (HRPC).

15 Jan 2009

Numerical analysis estimates numbers of older US adults who may benefit from statin therapy

Researchers estimate more than 11 million older Americans may be newly eligible for statin therapy if findings from a recently published large clinical trial are adopted into clinical practice guidelines, according to a new analysis of the trial data.

13 Jan 2009

Certain fatty acids help neurodevelopment for preterm girls

Preterm infant girls who received a high amount of dietary docosahexaenoic acid (DHA; an omega-3 fatty acid) had higher measures of neurodevelopment than preterm girls who received a standard amount of DHA, but this effect was not seen among preterm boys, according to a study in the January 14 issue of JAMA.

13 Jan 2009

Pfizer joins URMC initiative for safety of experimental drugs

Pfizer Inc. has agreed to provide the University of Rochester Medical Center (URMC) with a unique set of electrocardiographic data that will help researchers develop new methods to ensure the safety of experimental drugs.

12 Jan 2009

An explanation of how statins cause low rates of muscle symptoms

In the January 2009 issue of the American Journal of Medicine , Florida Atlantic University researcher Charles H. Hennekens, M.D., the first Sir Richard Doll Research Professor in the Charles E. Schmidt College of Biomedical Science and a renowned expert who has revealed numerous causal, therapeutic and preventive factors in the treatment and prevention of cardiovascular disease (CVD), most notably low-dose aspirin, explains why statins cause low rates of muscle symptoms.

9 Jan 2009

Placebo News and Research

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

FDA grants priority review of Cinryze C1 inhibitor as treatment for acute attacks of hereditary angioedema

Infliximab after intestinal resective surgery may help prevent post-op Crohn's disease recurrence

Study looks at acupuncture for pain

New bone cement may prevent amputations

Study of cannabinoid medicine for pain found patients got 'high,' but effects not related to pain relief

Early treatment with rasagiline (Azilect) for Parkinson's best

Inhaled corticosteroids reduces severity of asthma attacks in preschoolers

Can cognitive behavioural therapy help defeat depression?

Oral steroids ineffective treatment for wheezing in children

Anxious seniors may benefit from SSRIs

Cream containing tretinoin associated with death in clinical trial, but relationship does not appear causal

Savella - Fibromyalgia treatment approved by FDA

Depressed adolescents not harmed by being part of placebo group in clinical trial

Probiotics prevent IgE-associated allergy until age 5 in cesarean-delivered children but not in total cohort

Algeta completes phase II trial with Alpharadin for treating bone metastases in advanced prostate cancer

Numerical analysis estimates numbers of older US adults who may benefit from statin therapy

Certain fatty acids help neurodevelopment for preterm girls

Pfizer joins URMC initiative for safety of experimental drugs

An explanation of how statins cause low rates of muscle symptoms

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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