Protein C News and Research

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Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

Researchers comparatively assessed the generation of B lymphocyte-mediated antibody responses and T lymphocyte-mediated cellular responses between mRNA BNT162b vaccinees and mild COVID-19 patients.

21 Jun 2022

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

A new study reported four cases of Myelin Oligodendrocyte Glycoprotein-Associated Disorder that commenced after SARS-CoV-2 infection.

21 Jun 2022

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers evaluated the efficacy of PHELA, a traditional African drug, against SARS-CoV-2 in vitro.

21 Jun 2022

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

A recent article under review at the Nature Portfolio journal and currently available on the Research Square* preprint server analyzed the factors influencing the durability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitope-specific T cell reaction.

21 Jun 2022

UTSW study provides a potential avenue for the development of new antivirals against influenza

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of individuals worldwide each year and kills hundreds of thousands.

20 Jun 2022

Study offers new insight into the growth of blood vessels

Blood vessels must adapt their growth to the nutrients available in their surroundings so that they can keep organs adequately supplied. A team led by Michael Potente has identified two proteins that are important for this process and published their findings in Nature Metabolism.

20 Jun 2022

New model rapidly scans the genome of cancer cells and identifies mutations that drive tumor growth

Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

20 Jun 2022

MRI-based machine learning approach can accurately predict Alzheimer’s disease

The research uses machine learning technology to look at structural features within the brain, including in regions not previously associated with Alzheimer's.

20 Jun 2022

Implications of impaired type I interferon immunity and increasing COVID-19 severity

Researchers demonstrated that impaired type I interferon immunity is associated with increasing coronavirus disease 2019 severity.

20 Jun 2022

Genetic discovery may pave the way to new diagnostic approaches, treatments for motor neurone diseases

A new genetic discovery adds weight to a theory that motor neurone degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells.

20 Jun 2022

SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

In a recent study posted to the medRxiv* preprint server, researchers explored the association between circulating coronavirus disease 2019 (COVID-19) antigens and post-COVID-19 sequelae (long COVID).

20 Jun 2022

Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

In a recent study published in the journal Nature Medicine, researchers assessed the coronavirus disease 2019 (COVID-19) vaccine effectiveness (VE) against symptomatic infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and variants of interest (VOIs) by genetic mismatch/distance (GD) analysis.

20 Jun 2022

SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

In a recent study posted to the bioRxiv* preprint server, researchers at Weill Cornell Medical College assessed the cleavability of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and related coronaviruses by several proteases of the host.

19 Jun 2022

Gut microbiome acts on the brain to control appetite

Hypothalamic GABAergic neurons recognize microbial muropeptides through the cytosolic receptor NOD2, which regulates food intake and body temperature.

19 Jun 2022

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

In this new article publication from Acta Pharmaceutica Sinica B, authors Yun Yang, Danrong Hu, Yi Lu, Bingyang Chu, Xinlong He, Yu Chen, Yao Xiao, Chengli Yang, Kai Zhou, Liping Yuan and Zhiyong Qian from Sichuan University, Chengdu discuss tumor-targeted/reduction-triggered composite multifunctional nanoparticles for breast cancer chemo-photothermal combinational therapy.

18 Jun 2022

Protein C News and Research

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

UTSW study provides a potential avenue for the development of new antivirals against influenza

Study offers new insight into the growth of blood vessels

New model rapidly scans the genome of cancer cells and identifies mutations that drive tumor growth

MRI-based machine learning approach can accurately predict Alzheimer’s disease

Implications of impaired type I interferon immunity and increasing COVID-19 severity

Genetic discovery may pave the way to new diagnostic approaches, treatments for motor neurone diseases

SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

Gut microbiome acts on the brain to control appetite

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

Research may open door to the design of a better structured rabies vaccine

New discovery could lead to the development of therapeutic approaches for retinitis pigmentosa

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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