Inflammation News and Research

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Study explores the role of gut Piezo1 in sensing of bacterial RNA

In a new study published in Cell, "RNA sensing by gut Piezo1 is essential for systemic serotonin synthesis", a research team led by Kenta Maruyama M.D., Ph.D. from National Institute for Physiological Sciences explored the role of Piezo1, a mechano-sensing receptor, in the sensing of bacterial RNA.

7 Jul 2020

Cerebrospinal fluid autoantibodies target the brain in some COVID-19 patients

A study conducted by German researchers has shown that the neurological symptoms observed in some patients with coronavirus disease 2019 (COVID-19) may be caused by autoantibodies targeting the brain.

7 Jul 2020

Researchers develop peptides for treating gastrointestinal disorders

The fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders such as Crohn's disease.

7 Jul 2020

New nanoparticle-based artificial retina prosthesis restores vision in blind rats

An international team of scientists, of which the University of Granada (UGR) is a member, has developed a new nanoparticle-based artificial retina prosthesis that can be injected into the eye.

7 Jul 2020

New technique evaluates connectivity of brain networks in COVID-19 patients

Many patients with severe coronavirus disease in 2019 (COVID-19) remain unresponsive after surviving critical illness.

7 Jul 2020

Faulty immune response to SARS-CoV-2 one of the main causes of death

A new study published on the preprint server medRxiv in July 2020 describes the organ and tissue-specific spread of the virus causing the current COVID-19 pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Jul 2020

Dutch trial of convalescent plasma in COVID-19 discontinued

Now, a recent trial published on the preprint server medRxiv* in July 2020 reports that a majority of hospitalized COVID-19 patients have a high titer of neutralizing antibodies, at the time of admission, within 10 days of symptomatic disease.

7 Jul 2020

Study shows how non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation

Research from University of South Carolina associate professor Saurabh Chatterjee's laboratory in Environmental Health Sciences, Arnold School of Public Health, and led by Ayan Mondal, a postdoctoral researcher from the same lab, has revealed the cause behind the previously established link between non-alcoholic fatty liver disease (i.e., NAFLD, recently reclassified as metabolic associated fatty liver disease or MAFLD) and neurological problems.

6 Jul 2020

$5 million gift aims to propel Lyme disease research and education

To the Fairbairns, the symptoms--debilitating fatigue, joint pain, cognitive problems--were as worrisome as they were mystifying. All four members of the family had them.

6 Jul 2020

COVID-19 complications may be associated with von Willebrand factor in the blood

Anna Aksenova, a senior research associate at the Laboratory of Amyloid Biology at St Petersburg University, has advanced a hypothesis that the severe course of COVID-19 may be associated with von Willebrand factor.

6 Jul 2020

New assay uses unique fluorescent tags to analyze multiple cell populations

An efficient, robust method of examining the interactions between cells uses fluorescent tagging to simultaneously analyze multiple cell populations, speeding up a once tedious and limiting process.

6 Jul 2020

Novel cell-based approach used to reverse age-related impairments in animal model

Elderly people are more prone to infectious diseases as the function of their immune system continuously declines with progression of age.

6 Jul 2020

Asthma does not appear to increase the risk of COVID-19, shows study

Asthma does not appear to increase the risk for a person contracting COVID-19 or influence its severity, according to a team of Rutgers researchers.

6 Jul 2020

Researchers isolate protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

3 Jul 2020

New treatment approach for Alzheimer's disease

A new study published in The Journal of Physiology has shown that misfolded protein build-up in the gut could contribute to the development of Alzheimer's-like symptoms in mice.

3 Jul 2020

New drug discovery shows promise in fighting acute respiratory illnesses

A collaboration between the University of Toronto's Faculty of Dentistry and the National Jewish Health in Denver -- the top-ranked respiratory research hospital in the U.S. -- has yielded a new drug discovery that could be useful to combat inflammation of all varieties and shows promise in fighting acute respiratory illnesses such as COVID-19.

2 Jul 2020

Researchers unravel how the body fights off urinary tract infections

Anyone who has ever had cystitis knows that urinary tract infections of this kind are annoying and painful. They can be well treated by antibiotics, but may be fatal if left untreated.

2 Jul 2020

Eating black raspberries may reduce skin inflammation associated with allergies, study shows

Eating black raspberries might reduce inflammation associated with skin allergies, a new study indicates.

2 Jul 2020

Study: Oats and rye brans reduce weight gain, hepatic inflammation

In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

2 Jul 2020

SARS-CoV-2 infection modeling in iPSC-derived type 2 cells

The most fatal form of COVID-19 disease is acute respiratory distress syndrome (ARDS), caused by direct viral injury as well as indirect noxious effects caused by cytotoxic chemicals and inflammatory processes. A new study published on the preprint server bioRxiv* in June 2020 shows that this is partly due to the rapid onset of inflammation caused by the infection of type 2 alveolar cells with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Jul 2020