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Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

In a recent study posted to the bioRxiv* pre-print server, researchers at Cornell University College of Veterinary Medicine and the University of Illinois Urbana-Champaign compared the infection dynamics, pathogenicity, and tissue tropism of multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in adult cats.

17 Jun 2022

GPR183 gene a novel drug target for severe COVID-19

In a recent study posted to the bioRxiv* pre-print server, researchers provide the first preclinical evidence of the usefulness of antagonists of G-protein coupled receptor 183 (GPR183), also known as Epstein-Barr virus-induced gene 2 (EBI2), in reducing coronavirus disease 2019 (COVID-19) severity.

17 Jun 2022

HIV coinfection significantly impacts B cell response to SARS-CoV-2

In recent research posted to the bioRxiv* preprint server, investigators confirmed that human immunodeficiency virus (HIV) co-infection alters B cell reaction in coronavirus disease 2019 (COVID-19).

17 Jun 2022

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

In a recent study posted to the bioRxiv* pre-print server, researchers developed a novel Binding Activated Tandem split enzyme (BAT) biosensor for the detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein.

16 Jun 2022

New research helps to better understand the basic biology of nerve cells

Scientists are starting to understand the precise workings of a type of gene that, unlike other genes, does not code for proteins – the building blocks of life.

16 Jun 2022

Glucose meter can detect SARS-CoV-2 antibodies in patient samples

Over-the-counter COVID tests can quickly show whether you are infected with SARS-CoV-2. But if you have a positive result, there's no equivalent at-home test to assess how long you're protected against reinfection.

16 Jun 2022

How does gut microbiota impact mental health in 18–25s?

In a recently published article in the International Journal of Molecular Sciences, scientists have described the importance of the gut-brain-microbiota axis in establishing optimal mental health in emerging adulthood (ages 18–25).

16 Jun 2022

New liquid biopsy assay enables prediction of treatment response in patients with esophageal cancer

Biomarkers are like the X on a treasure map, but instead of indicating the location of unearthed riches, they indicate an individual's health status.

16 Jun 2022

NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

A new study explores the role of non-structural protein 1 (NSP1) in SARS-CoV-2 infection and pathogenesis.

16 Jun 2022

Oral immunotherapy for peanut allergies is highly effective when started for infants under 12 months

UBC researchers demonstrated in 2019 that pre-schoolers can safely overcome peanut allergies with a treatment called oral immunotherapy.

16 Jun 2022

Type I interferons play crucial role in fending off SARS-CoV-2

Researchers investigated whether individuals with breakthrough infections of COVID-19 pneumonia demonstrated normal antibody responses to vaccinations and whether they harbored type I interferon-neutralizing auto-antibodies.

16 Jun 2022

Study underpins use of primary SARS-CoV-2 vaccinations and booster doses during pregnancy

Researchers evaluated the immune responses to COVID-19 primary vaccinations and booster doses during pregnancy and the impact of the maternal booster dose on transplacental antibody transfer to the infant in the US.

16 Jun 2022

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Researchers assessed the efficiency of a hybrid vaccine against influenza and COVID-19 viruses.

16 Jun 2022

New component of cell death process could play key role in infection-fighting strategy

Researchers have unmasked a component of the cell death process that could play a vital role in a better infection-fighting strategy.

16 Jun 2022

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

Researchers found that immune-boosting by SARS-CoV-2 Omicron variant is contingent on prior COVID-19 history.

16 Jun 2022

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

In a recent study posted to the bioRxiv* pre-print server, researchers illustrated the cryo-electron microscopic (cryo-EM) structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein in lipid nanodiscs to 3.5 angstroms (Å) resolution.

16 Jun 2022

Research suggests profound SARS-CoV-2 mutations are rare even among immunosuppressed

A recent article posted to the medRxiv* preprint server assessed whether host traits like immunosuppression aids severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutational drift.

16 Jun 2022

Moffitt researchers reveal a mechanism leading to drug resistance in prostate cancer

Prostate cancer is the most common cancer among men in the United States. Many patients can live long lives due to early detection and treatment with androgen deprivation therapy.

16 Jun 2022

Fc-effector functions for selecting COVID-19 convalescent plasma

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that coronavirus disease 2019 (COVID-19) convalescent plasmas (CCPs) with low neutralizing and high fragment crystallizable (Fc)-effector activity result in effective prophylaxis.

15 Jun 2022

SARS-CoV-2 damages cilia

Researchers determine whether the interaction between ORF10 and ZYG11B promotes the dissemination of SARS-CoV-2.

15 Jun 2022

Protein C News and Research

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

GPR183 gene a novel drug target for severe COVID-19

HIV coinfection significantly impacts B cell response to SARS-CoV-2

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

New research helps to better understand the basic biology of nerve cells

Glucose meter can detect SARS-CoV-2 antibodies in patient samples

How does gut microbiota impact mental health in 18–25s?

New liquid biopsy assay enables prediction of treatment response in patients with esophageal cancer

NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

Oral immunotherapy for peanut allergies is highly effective when started for infants under 12 months

Type I interferons play crucial role in fending off SARS-CoV-2

Study underpins use of primary SARS-CoV-2 vaccinations and booster doses during pregnancy

Effectiveness of a hybrid vaccine against COVID-19 and influenza

New component of cell death process could play key role in infection-fighting strategy

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

Research suggests profound SARS-CoV-2 mutations are rare even among immunosuppressed

Moffitt researchers reveal a mechanism leading to drug resistance in prostate cancer

Fc-effector functions for selecting COVID-19 convalescent plasma

SARS-CoV-2 damages cilia

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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