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Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma.

27 Jan 2022

ANU researchers identify why Th17 cells go rogue and promote the onset of multiple sclerosis

Researchers from The Australian National University (ANU) have identified why certain cells in the body, known as Th17 cells, go rogue and promote the onset of autoimmune diseases such as multiple sclerosis (MS).

27 Jan 2022

Death rates from ovarian cancer are predicted to fall by 2022 in EU countries

Death rates from ovarian cancer are predicted to fall by 17% in the UK and by 7% in EU countries in 2022 compared to 2017, according to new research published in the leading cancer journal Annals of Oncology today (Wednesday).

27 Jan 2022

Study helps understand how smoking can lead to an increased risk of heart attacks

Smoking cigarettes may increase the risk of a heart attack by activating a gene that affects blood clotting, according to a new study by scientists at the University of Bristol.

26 Jan 2022

Microbiome 'profiling' may help identify people at risk of long COVID

The make-up of the gut microbiome may be linked to a person's risk of developing 'long COVID' many months after initial infection with SARS-CoV-2, the virus responsible for COVID-19 infection, suggests research published online in the journal Gut.

26 Jan 2022

Research reveals the burden of aortic valve stenosis in the UK

An estimated 300,000 people in the UK have aortic valve stenosis, a progressive and potentially fatal condition, suggests research published in the open access journal Open Heart.

26 Jan 2022

Macromolecular gel with therapeutic payload could halt or slow post-traumatic osteoarthritis

Osteoarthritis affects over 32 million Americans, levying a huge cost on society. Unfortunately, other than analgesics, no pharmaceutical therapy exists that can slow or halt disease progression of a major subset of OA: post-traumatic osteoarthritis (PTOA).

26 Jan 2022

CDC tells pharmacies to give 4th covid shots to immunocompromised patients

The Centers for Disease Control and Prevention reached out to pharmacists Wednesday to reinforce the message that people with moderate to severe immune suppression are eligible for fourth covid shots.

26 Jan 2022

More than 5,000 people enrolled in PANORAMIC study for COVID-19 antivirals

Over 5,000 vulnerable people have now enrolled into a world-class study for the chance to receive life-saving antivirals, the government has announced today (Wednesday 26 January 2022).

26 Jan 2022

Evaluating the use of megadoses of corticosteroids as a treatment of COVID-19

In a new study, researchers have been investigating the effects of megadoses of corticosteroids on hospitalized COVID-19 patients.

26 Jan 2022

New report investigates how genomics could play a part in our lives in the future

A new wide-ranging report Genomics Beyond Health published today by the Government Office for Science investigates how genomics could play a part in our lives in the future, from sport to education and tackling crime.

25 Jan 2022

COVID-19 research made easier with outbreak.info

In a recent paper posted to the bioRxiv* preprint server, researchers reveal the development of an open-source database that provides data on coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) resources.

25 Jan 2022

Scientists explore how proteins bind with specific companions inside cells

Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of which interact with partner proteins to mediate upwards of 400,000 distinct interactions.

25 Jan 2022

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

A new study looks at the molecular level inhibition of the protective CFTR gene by the SARS-CoV-2 spike protein.

25 Jan 2022

Pharmacies are turning away immunocompromised patients seeking 4th covid shot

Patients with weakened immune systems — who are at high risk from covid-19 — say pharmacies are turning them away when they seek additional vaccine doses recommended by federal health officials.

25 Jan 2022

I write about America’s absurd health care system. Then I got caught up in it.

I got a hurried voicemail from my pharmacist in Wisconsin the day before Thanksgiving letting me know my insurance was refusing to cover my insulin.

25 Jan 2022

New therapeutic approach offers hope to treat obesity and related metabolic disorders

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new therapeutic approach to obesity and related metabolic disorders that in laboratory experiments demonstrated a significant reduction in body fat, body weight, and improvement in the blood markers that accompany these disorders.

25 Jan 2022

Neurological complications of the SARS-CoV-2 vaccine

In a study published in the latest issue of the journal Neurological Sciences, a team of researchers described a three-patient case series presenting with neurological manifestations after the coronavirus disease 2019 (COVID-19) vaccination, followed by a literature review, to propose hypotheses on how neurological symptoms might develop after vaccination.

24 Jan 2022

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Protein misfolding is a likely culprit in many degenerative disorders. Cystic fibrosis, for instance, is caused by mutations in the CFTR gene that prevent the eponymous protein from assuming its proper configuration.

24 Jan 2022

Eligible adults urged to take part in world-first COVID-19 study of antivirals

Adults over the age of 50 or with an underlying health condition who test positive for COVID-19 are being urged to sign up for a world-first COVID-19 study which is providing life-saving antivirals to thousands of people.

24 Jan 2022