Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Positive results from Bionovo's Menerba tolerability trial on menopausal hot flashes

Bionovo, Inc., a pharmaceutical company focused on the discovery and development of safe and effective treatments for women's health and cancer, today announced the positive results from the completion of their tolerability trial of Menerba (MF101) for menopausal hot flashes.

31 Aug 2011

Favorable top-line results from Aeterna Zentaris' AEZS-130 Phase 3 study on AGHD

Aeterna Zentaris Inc. today announced favorable top-line results of its completed Phase 3 study with AEZS-130 as the first oral diagnostic test for Adult Growth Hormone Deficiency.

31 Aug 2011

New chemical compounds show promise against set of protein-folding diseases

Collaborating researchers at Stanford University and The Scripps Research Institute have identified chemical compounds that show promise as potential therapeutics for a set of medical conditions caused by the abnormal clumping together of a protein known as transthyretin.

30 Aug 2011

Low-glycemic foods, high protein intake reduce body weight and fat mass

A new study out of Madrid, Spain shows that low-glycemic foods, and moderately high-protein intake has been shown to reduce body weight and fat mass.

29 Aug 2011

Elevating free radical levels suppresses appetite in obese mice

Obesity is growing at alarming rates worldwide, and the biggest culprit is overeating. In a study of brain circuits that control hunger and satiety, Yale School of Medicine researchers have found that molecular mechanisms controlling free radicals-molecules tied to aging and tissue damage-are at the heart of increased appetite in diet-induced obesity.

29 Aug 2011

GCC hormone receptor may also help fight obesity

The hormone receptor guanylyl cyclase C (GCC) has been established as a suppressor of colorectal cancer tumors, but new evidence from Thomas Jefferson University suggests it may also help fight one of the country's biggest pandemics: obesity.

26 Aug 2011

Boehringer Ingelheim, Lilly receive EU approval for linagliptin to treat type 2 diabetes

Boehringer Ingelheim and Eli Lilly and Company today received Marketing Authorization from the European Commission for linagliptin 5 mg film-coated tablets for the treatment of adults with type 2 diabetes.

26 Aug 2011

ICU patients less likely to renew prescriptions for chronic diseases after discharge

Patients often do not renew prescriptions for their chronic diseases after they are released from hospital.

25 Aug 2011

IGF1 plays key role in T-cell acute lymphoblastic leukemia

There are numerous specialized growth factors that are responsible for cells of different tissues of our body to divide and differentiate when needed. These hormone-like factors bind to matching receptors on the surface of their target cells and thus give order for the cell to divide. However, a single genetic alteration can be sufficient for the whole system to get out of control.

24 Aug 2011

Avastin increases tumor response rates in breast cancer patients before surgery

Amid the controversy surrounding the Food and Drug Administration's ruling that Avastin should no longer be used to treat metastatic breast cancer, a new multinational Phase III clinical trial shows that Avastin significantly increased tumor response rates in breast cancer patients when given before surgery.

24 Aug 2011

Helsinn begins enrollment in anamorelin Phase III trial for NSCLC-associated anorexia/cachexia

Helsinn, a Swiss-based pharmaceutical company, announced today that its US subsidiary, Helsinn Therapeutics, has enrolled the first patient in the company's pivotal Phase III clinical program of anamorelin HCl for the treatment of anorexia/cachexia in patients with advanced non-small cell lung cancer.

23 Aug 2011

Molecular Endocrinology journal publishes two studies on estrogen hormones

University of Houston (UH) researchers have their sights set on developing possible treatments for breast and colon cancer.

23 Aug 2011

Radium-223 chloride granted FDA Fast Track designation for treatment of CRPC

Algeta ASA, a company focused on the development of novel targeted cancer therapeutics, today announced that radium-223 chloride has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for the treatment of castration-resistant (hormone refractory) prostate cancer in patients with bone metastases.

23 Aug 2011

Scientists identify molecular pathway that plays a key role in stress-related DNA damage

Working closely with a team of researchers from Duke University, scientists from the Florida campus of The Scripps Research Institute have helped identify a molecular pathway that plays a key role in stress-related damage to the genome, the entirety of an organism's hereditary information.

23 Aug 2011

Tiny molecule could bind to B cell EB12 receptor and prevent cancer

Infection with Epstein Barr means that the B cells, which are the primary memory cells of the immune system, are hi-jacked. When the virus has penetrated, researchers observe an excess of a special bio-antenna, a receptor known as EB12, suddenly sprouting from the surface of the B cells. But why they do so remains a mystery.

22 Aug 2011

Decline in HT use could lead to lower mammogram rates among women

A new analysis has found that a decline in hormone therapy (HT) use among women aged 50 to 64 years is linked with lower mammogram rates among these women.

22 Aug 2011

Combination of exercise and metformin less effective for people with diabetes

It's common enough for researchers to look at the impacts of prescribed drugs on the body. And if you're a diabetes researcher who believes that exercise has great benefits for those with type 2 diabetes, you're hoping your research will show that. But when Normand Boul- looked at the dual impacts of exercise and metformin - two of the most commonly-prescribed modalities for glucose control - on that very outcome, the hoped-for double whammy wasn't the result.

20 Aug 2011

News highlights: Calif. ruling limits medical damages; appeal filed in case challenging Ariz. Medicaid cuts

The state Supreme Court handed insurers and business groups a major legal victory -- and personal injury lawyers an equally big setback -- on Thursday by imposing limits on medical damages in one of the era's closest watched civil cases. The issue in the case, Howell v. Hamilton Meats & Provisions, was whether an injured party could collect the full medical care costs billed by doctors and hospitals, or the lesser amount that the medical providers accepted from an insurance company.

20 Aug 2011

Dissimilar interaction of opioid receptors may explain why men, women experience pain differently

Women and men experience pain, particularly chronic pain, very differently. The ability of some opioids to relieve pain also differs between women and men. While it has been recognized since the mid-nineties that some narcotic analgesics are more effective in women than men, the reason for this difference was largely unknown.

19 Aug 2011

Conference to discuss latest research on gender disparities in cardiovascular disease

Heart disease has sometimes been considered a men's health issue, but the statistics prove otherwise. In the US alone, more than 42 million women live with the problem. Heart disease is responsible for more than one-third of deaths among American women each year, making it the number one killer of females older than 20.

19 Aug 2011

Hormone News and Research

Further Reading

Positive results from Bionovo's Menerba tolerability trial on menopausal hot flashes

Favorable top-line results from Aeterna Zentaris' AEZS-130 Phase 3 study on AGHD

New chemical compounds show promise against set of protein-folding diseases

Low-glycemic foods, high protein intake reduce body weight and fat mass

Elevating free radical levels suppresses appetite in obese mice

GCC hormone receptor may also help fight obesity

Boehringer Ingelheim, Lilly receive EU approval for linagliptin to treat type 2 diabetes

ICU patients less likely to renew prescriptions for chronic diseases after discharge

IGF1 plays key role in T-cell acute lymphoblastic leukemia

Avastin increases tumor response rates in breast cancer patients before surgery

Helsinn begins enrollment in anamorelin Phase III trial for NSCLC-associated anorexia/cachexia

Molecular Endocrinology journal publishes two studies on estrogen hormones

Radium-223 chloride granted FDA Fast Track designation for treatment of CRPC

Scientists identify molecular pathway that plays a key role in stress-related DNA damage

Tiny molecule could bind to B cell EB12 receptor and prevent cancer

Decline in HT use could lead to lower mammogram rates among women

Combination of exercise and metformin less effective for people with diabetes

News highlights: Calif. ruling limits medical damages; appeal filed in case challenging Ariz. Medicaid cuts

Dissimilar interaction of opioid receptors may explain why men, women experience pain differently

Conference to discuss latest research on gender disparities in cardiovascular disease

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