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Nanoparticle delivery of a fully functioning copy of P53 tumor suppressor gene

Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing normal tissue April 21 at an American Association of Anatomists (AAA) scientific session at Experimental Biology 2009 in New Orleans.

20 Apr 2009

Discovery of nine new genes on X chromosome that, when knocked-out, lead to learning disabilities

The international team studied almost all X chromosome genes in 208 families with learning disabilities - the largest screen of this type ever reported.

20 Apr 2009

Vegan nuns found to have same bone density as non-vegans

A study comparing the bone health of 105 post-menopausal vegan Buddhist nuns and 105 non-vegetarian women, matched in every other physical respect, has produced a surprising result.

16 Apr 2009

Singapore scientists synthesize gold to shed light on cells' inner workings

Highly fluorescent gold nanoclusters for sub-cellular imaging have been synthesized by researchers at the Institute of Bioengineering and Nanotechnology (IBN), one of the research institutes of Singapore's A*STAR (Agency for Science, Technology and Research).

16 Apr 2009

Autopsy study links prostate cancer to single rogue cell

One cell…one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer.

16 Apr 2009

Autopsy study links prostate cancer to single rogue cell

One cell...one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer. Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease. Culling information from autopsies, their study points to a set of genetic defects in a single cell that are different for each person's cancer.

16 Apr 2009

Rochester scientist wins major award for Alzheimer's research

A Rochester researcher whose work has opened up a whole new avenue in Alzheimer's disease research has received a major prize from the American Academy of Neurology.

15 Apr 2009

Surgery for obesity

Surgeons once recommended weight-loss surgery only for severely obese patients who failed to drop pounds with conventional weight-loss methods, but a review now finds that bariatric surgery helps the moderately obese lose more weight, too.

14 Apr 2009

Statins for the prevention of dementia

An increasing number of studies show that elevated serum cholesterol levels might be part of the cause of Alzheimer's disease, but a new review of studies says that, even so, the most successful class of cholesterol-lowering medicines will not stave off the condition.

14 Apr 2009

Maternal positions and mobility during first stage of labor

Women who walk, sit, kneel or otherwise avoid lying in bed during early labor can shorten the first stage of labor by about an hour, according to a new Cochrane evidence review.

14 Apr 2009

New AIDS research training grants awarded for projects in 15 countries

The Fogarty International Center of the National Institutes of Health has awarded seven grants totaling almost $2.7 million to train HIV/AIDS researchers in 15 low- and middle-income countries.

14 Apr 2009

HIV infection rates are lower in circumcised heterosexual men

Three recent African trials support male circumcision for reducing the risk of contracting HIV in heterosexual men.

14 Apr 2009

Music for stress and anxiety reduction in coronary heart disease patients

The right mix of Portuguese instrumentals calms Philadelphia researcher Joke Bradt.

14 Apr 2009

Creating ideal neural cells for clinical use

Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation.

13 Apr 2009

Elderly Australians a tough bunch!

Australian researchers say elderly Australians are tougher than is often assumed and are more resilient than people think.

13 Apr 2009

Australian study will explore genetic causes of ADHD

New research planned by Australian scientists will hopefully shed some light on the causes of Attention Deficit Hyperactivity Disorder (ADHD).

13 Apr 2009

Omega-3 fatty acids may help cancer patients undergoing major operations

New research from Trinity College Dublin published in this month's Annals of Surgery points to a potentially significant advance in the treatment of patients undergoing major cancer surgery.

12 Apr 2009

New method predicts impact of anthrax release

A new statistical method that can estimate the origin and time of an aerosolized release of the pathogen causing anthrax, following detection of the first few cases has been developed by researchers from the Medical Research Council (MRC) Centre for Outbreak Analysis and Modelling at Imperial College London in collaboration with the Health Protection Agency's Microbial Risk Assessment group.

12 Apr 2009

Research points to a new approach to treating type 1 diabetes

Scientists at Burnham Institute for Medical Research (Burnham) and the University of California San Diego (UC San Diego) School of Medicine have demonstrated in mice that transplanted pancreatic precursor cells are protected from the immune system when encapsulated in polytetrafluorethylene (PTFE).

12 Apr 2009

Scientists discover the secrets of NF-kappaB

A study published in Science examines a key player in conditions such as cancer, inflammatory bowel disease, rheumatoid arthritis and asthma and has shown that cells use a sophisticated communication system to coordinate responses to infection and maintain inflammation in the body.

12 Apr 2009