Protein C News and Research

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The severity of COVID-19 compared to seasonal influenza

In a recent study under review at the Archives of Virology journal and currently posted to the Research Square* preprint server, investigators in Israel assessed the disparities and similarities between seasonal influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

14 Jun 2022

Genomic analysis of the 2022 monkeypox outbreak

In a recent study posted to the bioRxiv* pre-print server, researchers analyzed two genomic sequences of the Monkeypox virus from Belgium and Portugal termed ITM001 and PT0001, respectively, to show that the May 2022 Monkeypox outbreak most likely originated from the West African clade of the virus.

14 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

SARS-CoV-2 recombinant isolated from chronic COVID-19 patient

A new research paper in the journal Viruses reports the isolation of a recombinant strain in a patient infected with the virus for over a year.

13 Jun 2022

Study demonstrates a potential way to stimulate the formation of new insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.

13 Jun 2022

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to treat the human condition according to data being presented Monday, June 13 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers

Advances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers.

13 Jun 2022

Social stress factors have a direct impact on cellular mechanisms that drive deadly breast cancer

Chronically stressful conditions of daily life such as racism, pollution and poverty have a direct impact on the cellular mechanisms that drive lethal, invasive forms of breast cancer, according to a study led by Duke Cancer Institute researchers.

13 Jun 2022

Evosep One enables robust, high throughput, single cell proteomics

Today, at the 70th Conference on Mass Spectrometry and Allied Topics, Evosep demonstrates new applications for standardization of high throughput single cell proteomics, higher throughput clinical analysis, and improved diabetes monitoring.

From Evosep 13 Jun 2022

The potential role of Ginkgo biloba L. folium extract in the management of COVID-19

Researchers explored the effectiveness of Ginkgo biloba L. folium extract (EGb) in the management of COVID-19 severity.

13 Jun 2022

Study shows safety of COVID-19 vaccines for patients treated for hypothyroidism

Inactivated and mRNA COVID-19 vaccines appear to be safe for patients treated for hypothyroidism, according to a new study being presented at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

SARS-CoV-2 BA.4/5 variants escape vaccine and BA.1 infection induced antibodies

In a recent work published in the Cell journal, investigators examined the severe acute respiratory syndrome coronavirus (SARS-CoV-2) Omicron BA.5/4 variants escape from neutralizing antibodies induced by SARS-CoV-2 vaccines and natural infection.

13 Jun 2022

Gut microbiome may be the "black box" of nutrition research

In a recent paper published in the Cell journal, researchers at the University of Alberta, Canada, and the University College Cork, Ireland, analyzed the current nutritional guidelines for gut microbiota.

13 Jun 2022

Animal study suggests intranasal COVID vaccine delivery more efficient than intramuscular

In a recent study published in the journal PNAS, researchers demonstrated higher comparative efficacy of the intranasal (IN) route of coronavirus disease 2019 (COVID-19) vaccine administration versus intramuscular route in mice.

12 Jun 2022

New molecule kills a broad spectrum of hard-to-treat cancers

A new molecule synthesized by a University of Texas at Dallas researcher kills a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Stress protein in fibroblasts appears to be an attractive cancer drug target

A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

10 Jun 2022

Protein C News and Research

The severity of COVID-19 compared to seasonal influenza

Genomic analysis of the 2022 monkeypox outbreak

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

SARS-CoV-2 recombinant isolated from chronic COVID-19 patient

Study demonstrates a potential way to stimulate the formation of new insulin-producing cells

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers

Social stress factors have a direct impact on cellular mechanisms that drive deadly breast cancer

Evosep One enables robust, high throughput, single cell proteomics

The potential role of Ginkgo biloba L. folium extract in the management of COVID-19

Study shows safety of COVID-19 vaccines for patients treated for hypothyroidism

SARS-CoV-2 BA.4/5 variants escape vaccine and BA.1 infection induced antibodies

Gut microbiome may be the "black box" of nutrition research

Animal study suggests intranasal COVID vaccine delivery more efficient than intramuscular

New molecule kills a broad spectrum of hard-to-treat cancers

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Stress protein in fibroblasts appears to be an attractive cancer drug target

Deciphering the structure of nuclear pore complex piece by piece

Creating CAR T cells without an immune brake

Study reveals the benefits of using thalidomide in patients with severe arteriovenous malformations

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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