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Mayo Clinic researchers examine how human factors contribute to surgical errors

Why are major surgical errors called "never events?" Because they shouldn't happen — but do. Mayo Clinic researchers identified 69 never events among 1.5 million invasive procedures performed over five years and detailed why each occurred. Using a system created to investigate military plane crashes, they coded the human behaviors involved to identify any environmental, organizational, job and individual characteristics that led to the never events.

2 Jun 2015

Gaumard Scientific's installations of Victoria birthing simulator continue at rapid pace in the U.S.

Gaumard Scientific Company today announced that its U.S. installations of the Victoria birthing simulator continue at a rapid pace as more health care educators select what is the industry's most advanced maternal-fetal simulator for their teaching purposes. Victoria installations now span 24 states in all regions and reflect the demand for advanced fully tetherless and wireless technology that Gaumard offers.

2 Jun 2015

Talimogene laherparepvec treatment shows durable clinical responses in advanced-stage melanoma patients

Research led by Howard L. Kaufman, MD, FACS, associate director for clinical science and chief surgical officer at Rutgers Cancer Institute of New Jersey and colleagues, shows advanced-stage melanoma patients have significant improvement in durable response rate and a trend toward improved survival when treated with a genetically-modified form of a herpes virus, whose native form causes the common cold sore.

2 Jun 2015

New tool kit aims to support family planning efforts

In developing regions where the economy is weak and medical services are limited, global health experts say as many as 200 million women want access to long-term, reversible contraceptives to avoid unintended pregnancies and to help space out the births of their children.

2 Jun 2015

Combination of Tafinlar and Mekinist drugs improves outcomes in patients with metastatic melanoma

Novartis today announced data from the Phase III COMBI-d study showing a significant survival benefit for patients with BRAF V600E/K mutation-positive metastatic melanoma when treated with the combination of Tafinlar (dabrafenib) and Mekinist (trametinib) compared to Tafinlar monotherapy alone.

2 Jun 2015

Chronic exposure to bacteria may lead to development of Type 2 diabetes

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers (H. pylori bacteria).

2 Jun 2015

Combination of cobimetinib and vemurafenib can halt progression of metastatic melanoma for one year

Data from the pivotal coBRIM Phase III study, presented by Lead Investigator Dr James Larkin today at the American Society of Clinical Oncology (ASCO) annual meeting, demonstrate that Roche’s investigational MEK inhibitor cobimetinib, used in combination with BRAF inhibitor vemurafenib, typically offers people with previously untreated advanced metastatic melanoma (BRAFV600 mutation-positive unresectable or metastatic) one full year (median 12.3 months) without their disease worsening.

2 Jun 2015

Plastic surgeries in the US surge due to increase in weight loss surgeries

An increase in the number of weight loss surgeries in the U.S. is beginning to have a ripple effect in plastic surgery, according to new data released today by the American Society of Plastic Surgeons (ASPS). Procedures specifically associated with massive weight loss, including tummy tucks, thigh lifts, breast lifts and upper arm lifts, grew at their fastest rate in four years in 2014, according to the report. That follows a similar increase in the growth of weight loss surgeries.

1 Jun 2015

Pennsylvania physicians urge residents to take precautions against bug bites, bee stings

For many people, bug bites and bee stings aren't a big deal beyond a small irritation. But for some, it could mean the start of a painful - possibly long-term or even deadly - experience.

1 Jun 2015

Pharmacyclics’ Ibrutinib Phase Ib/II data show ibrutinib may be safe and effective in patients with cGVHD

Pharmacyclics LLC today announced interim results from the ongoing Phase Ib/II PCYC-1129 study suggesting that ibrutinib (IMBRUVICA) may be a safe and effective treatment for patients with chronic graft-versus-host-disease (cGVHD) who were either refractory to steroid treatment or were steroid-dependent.

1 Jun 2015

WBRT associated with worse cognitive function than radiosurgery, shows study

Whole Brain Radiation Therapy (WBRT) is associated with significantly worse cognitive function than radiosurgery, and should no longer be used in the adjuvant setting after radiosurgery to treat cancer patients with brain metastases, according to a large study led by a researcher at The University of Texas MD Anderson Cancer Center.

1 Jun 2015

Combination of Mekinist and Tafinlar drugs improves outcome in patients with metastatic melanoma

1 Jun 2015

Scientists develop human cortical spheroids

A patient tormented by suicidal thoughts gives his psychiatrist a few strands of his hair. She derives stem cells from them to grow budding brain tissue harboring the secrets of his unique illness in a petri dish. She uses the information to genetically engineer a personalized treatment to correct his brain circuit functioning. Just Sci-fi? Yes, but...

1 Jun 2015

NYU researchers identify root cause of eye infections among contact lens wearers

Using high-precision genetic tests to differentiate the thousands of bacteria that make up the human microbiome, researchers at NYU Langone Medical Center suggest that they have found a possible — and potentially surprising — root cause of the increased frequency of certain eye infections among contact lens wearers.

1 Jun 2015

CHEMOSAT treatment of UM patients with hepatic metastases highlighted at ASCO 2015

Delcath Systems, Inc., a specialty pharmaceutical and medical device company focused on oncology with an emphasis on the treatment of primary and metastatic liver cancers, announces that results of a large, European single-center experience of the treatment of uveal melanoma patients with hepatic metastases with the Delcath Hepatic CHEMOSAT® Delivery System, were highlighted in an on-line abstract at the American Society of Clinical Oncology Annual Meeting 2015.

1 Jun 2015

Caris Molecular Intelligence allows comparisons between tumors sharing histological features

Caris Life Sciences, a leading biotechnology company focused on fulfilling the promise of precision medicine, today announced the presentation of data from three studies that demonstrate the utility of Caris Molecular Intelligence®, the company's panomic comprehensive tumor profiling service, in facilitating comparisons between tumors that share histological features.

1 Jun 2015

Nanopatch Jet Coating drug delivery platform wins 2015 Good Design Award

Invetech, a leader in instrument development, custom automation, and contract manufacturing, and Vaxxas, a biotechnology start-up and developer of the Nanopatch™ needle-free drug delivery technology, have been named winners of the 2015 Good Design Award for development of the Nanopatch Jet Coating Instrument, an advanced technology platform to support needle-free dermal drug delivery research and product development. The award was announced last evening at the Good Design Awards Gala Night held in Sydney, Australia.

1 Jun 2015

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

The rapidly emerging field of precision medicine is a "disruptive innovation" that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine and executive vice president of the University of Pennsylvania for the Health System, in this week's issue of the New England Journal of Medicine.

1 Jun 2015

Novel biosensor chip measures pH, temperature, drugs and metabolism-related molecules

The future of medicine lies in ever greater precision, not only when it comes to diagnosis but also drug dosage. The blood work that medical staff rely on is generally a snapshot indicative of the moment the blood is drawn before it undergoes hours - or even days - of analysis.

30 May 2015

Acupuncture-like TENS may be effective for treating radiation-induced xerostomia

Phase III results of Radiation Therapy Oncology Group 0537 indicate that acupuncture-like, transcutaneous electrical nerve stimulation (ALTENS) may be equally effective as pilocarpine, the current prescription medication in a pill, to treat radiation-induced xerostomia (dry mouth), according to a study published in the June 1, 2015 issue of the International Journal of Radiation Oncology * Biology * Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology.

30 May 2015

Skin News and Research

Mayo Clinic researchers examine how human factors contribute to surgical errors

Gaumard Scientific's installations of Victoria birthing simulator continue at rapid pace in the U.S.

Talimogene laherparepvec treatment shows durable clinical responses in advanced-stage melanoma patients

New tool kit aims to support family planning efforts

Combination of Tafinlar and Mekinist drugs improves outcomes in patients with metastatic melanoma

Chronic exposure to bacteria may lead to development of Type 2 diabetes

Combination of cobimetinib and vemurafenib can halt progression of metastatic melanoma for one year

Plastic surgeries in the US surge due to increase in weight loss surgeries

Pennsylvania physicians urge residents to take precautions against bug bites, bee stings

Pharmacyclics’ Ibrutinib Phase Ib/II data show ibrutinib may be safe and effective in patients with cGVHD

WBRT associated with worse cognitive function than radiosurgery, shows study

Combination of Mekinist and Tafinlar drugs improves outcome in patients with metastatic melanoma

Scientists develop human cortical spheroids

NYU researchers identify root cause of eye infections among contact lens wearers

CHEMOSAT treatment of UM patients with hepatic metastases highlighted at ASCO 2015

Caris Molecular Intelligence allows comparisons between tumors sharing histological features

Nanopatch Jet Coating drug delivery platform wins 2015 Good Design Award

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

Novel biosensor chip measures pH, temperature, drugs and metabolism-related molecules

Acupuncture-like TENS may be effective for treating radiation-induced xerostomia

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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