Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Lab-grown mini tumors help scientists predict breast cancer treatment success

Researchers at UC San Francisco have developed a new method to predict how different types of breast cancer will respond to treatment, using patient data from the I-SPY2 breast cancer trial and rapid testing on lab-grown mini tumors.

11 Aug 2026

New multi-protein blood test accurately detects late-stage Alzheimer's disease

Researchers have identified seven proteins in the blood that could enable better blood tests for Alzheimer's disease.

11 Aug 2026

Semaglutide slows blood protein signature linked to future dementia risk

A post hoc analysis of 2,970 older SELECT participants found that semaglutide slowed worsening of a 25-protein blood signature that predicts future dementia risk. Over 104 weeks, semaglutide produced larger effects on modeled 5-year than 20-year dementia risk, but whether these biomarker changes translate into less cognitive decline or dementia remains unknown.

10 Aug 2026

Study uses alternative splicing data to predict protein function

A single human gene can produce multiple protein isoforms through alternative splicing, greatly expanding the functional diversity of the proteome.

10 Aug 2026

New partnership expands patient access to cancer clinical trials

The University of Chicago Medicine Comprehensive Cancer Center (UCCCC) and Eli Lilly and Company (Lilly) have partnered to help patients gain greater access to potential cancer treatments by participating in clinical trials.

10 Aug 2026

Spatial transcriptomics study elucidates cellular dynamics during heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

10 Aug 2026

Two-gene interaction reveals metastatic risk in breast cancer

Why do some breast cancer patients face a much higher risk of distant metastasis, while others with seemingly similar disease experience far better outcomes?

7 Aug 2026

Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target

Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome.

7 Aug 2026

Nicotine gum may make smokeless tobacco withdrawal easier to manage

A randomized trial found that 2 mg nicotine gum controlled craving, anxiety, and sleep problems more effectively than behavioral counselling during smokeless tobacco cessation. Although abstinence rates were numerically higher with nicotine gum, the differences were not statistically significant, highlighting the need for larger studies.

6 Aug 2026

D-serine promotes gastric cancer growth by suppressing tumor immunity

Researchers from Keio University have found that D-serine increases the growth of gastric cancer by creating an immunosuppressive and anti-inflammatory tumor microenvironment.

6 Aug 2026

Ferroptosis-based therapy shows promise for advanced prostate cancer treatment

A recent review explores the rapidly expanding field of ferroptosis-based therapy for prostate cancer, presenting ferroptosis as a promising strategy to overcome resistance in advanced and castration-resistant prostate cancer (CRPC).

6 Aug 2026

Advances in DNA technology are reshaping preventive healthcare

A new review highlights how advances in DNA technology are reshaping the future of healthcare by shifting the focus from treatment to prevention.

6 Aug 2026

HMGCR emerges as a promising target for precision cancer therapies

A growing body of evidence is reshaping how scientists and clinicians understand the role of cancer metabolism, placing the enzyme HMGCR at the center of a rapidly evolving therapeutic landscape.

5 Aug 2026

Versatile receptor protein plays critical role in regulating tissue repair

A comprehensive new review highlights the expanding importance of Lgr6, a member of the G protein-coupled receptor family, as a critical regulator of tissue homeostasis, injury repair, and disease development across multiple organ systems.

5 Aug 2026

New metric detects early Alzheimer’s changes in brain's white matter

Alzheimer's disease has traditionally been studied as a condition that primarily affects the brain's gray matter, where neuronal cell bodies are located and some of the disease's most characteristic lesions accumulate.

5 Aug 2026

Sino Biological launches precisely characterized full-length p-Tau217 protein to advance next-generation Alzheimer’s Biomarker assay development

Sino Biological Inc. is pleased to announce the launch of its Recombinant Human p-Tau217 Protein (Cat. No. T08-50SN), a full-length, tag-free Tau reagent developed to support Alzheimer’s disease biomarker assay development, antibody evaluation, and Tau biology research.

From Sino Biological Inc. 4 Aug 2026

Study links lower vitamin D to mood and cognitive health in adults over 85 with diabetes

Researchers studying 188 adults aged 85 years or older with type 2 diabetes found the lowest serum 25(OH)D concentrations among those with both depressive symptoms and mild cognitive impairment. Lower levels remained associated with having both conditions after adjustment for selected factors, but the cross-sectional study cannot establish causation or a benefit from supplementation.

3 Aug 2026