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Study identifies new drug to halt dementia in athletes after repeated head injuries

A world-first international study led by the University of South Australia has identified a new drug to stop athletes from developing dementia after sustaining repeated head injuries in their career.

7 Jun 2021

New insights into white matter changes may offer novel targets for prevention, therapies

ince 2008, researchers at Boston University School of Medicine (BUSM) and VA Boston Healthcare System have studied Chronic Traumatic Encephalopathy (CTE), a progressive brain disease associated with repetitive head impacts that has been diagnosed after death in the brains of American football players and other contact sport athletes as well as members of the armed services.

25 May 2021

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

The blood-brain barrier is an impenetrable barrier between the circulating blood and the brain established before birth that prevents immune cells from entering the brain from the body's immune system. Thus, the brain has its own immune system with a key actor called microglia.

21 May 2021

Cognitive problems caused by repetitive and mild blows to the head could be treated, study suggests

A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified.

10 May 2021

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways.

7 May 2021

Trouble managing money may be an early sign of dementia

After Maria Turner's minivan was totaled in an accident a dozen years ago, she grew impatient waiting for the insurance company to process the claim.

5 May 2021

FDA authorizes marketing of a new device for use in patients undergoing stroke rehabilitation

Today, the U.S. Food and Drug Administration authorized marketing of a new device indicated for use in patients 18 and older undergoing stroke rehabilitation to facilitate muscle re-education and for maintaining or increasing range of motion.

23 Apr 2021

Researchers identify the cause of severe canine juvenile epilepsy

In a study conducted at the University of Helsinki, researchers found a cause for severe epilepsy resulting in death in Parson Russell Terrier puppies at a few months of age. A change in the PITRM1 gene can lead to a dysfunction of mitochondria, the cellular energy pumps.

21 Apr 2021

Study: Age-related changes in brain stem cells are more pronounced in male animals

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis. This process is important for learning and cognitive function which declines as the brain ages.

9 Apr 2021

Memory and executive function symptoms are valuable for predicting CTE pathology, suggests study

Diagnosing Chronic Traumatic Encephalopathy (CTE) during life is crucial for developing therapies and for determining how common the disease is among individuals exposed to repetitive head impacts from contact sports, military service and physical violence.

7 Apr 2021

Study reveals sex-differences in aging of the brain stem cell niche

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis.

7 Apr 2021

Study shows persisting cognitive benefits of common Alzheimer’s treatment

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer's disease, but their effects on cognition have been debated and few studies have investigated their long-term effects.

25 Mar 2021

Human cerebral organoid model to screen drugs for treatment of Creutzfeldt-Jakob disease

Approximately two years after establishing a human cerebral organoid system to study Creutzfeldt-Jakob disease (CJD), National Institutes of Health researchers have further developed the model to screen drugs for potential CJD treatment.

9 Mar 2021

Rare Disease Day 2021: Raising awareness of childhood dementia

In the lead-up to Rare Diseases Day – on Sunday February 28 - Associate Professor Kim Hemsley’s studies into childhood dementia are helping to unlock answers that can assist treatment of these largely unheralded conditions.

25 Feb 2021

In Vivo Probes for Detecting Inflammation Markers in Humans and Animals

News-Medical talks to Parry Hashemi about research on in vivo probes for detecting inflammation markers in humans and animals she will present at Pittcon.

From Pittcon 24 Feb 2021

Study finds link between brain metabolism, cardiovascular risk, and atherosclerosis

The links between cardiovascular disease and cognitive impairment begin years before the appearance of the first clinical symptoms of either condition.

15 Feb 2021

New review recommends a holistic approach to manage cerebral small vessel disease

Cerebral small vessel disease (SVD) is characterized by damage to the blood vessels and parenchyma in the brain. It presents as a multitude of symptoms, which makes the diagnosis difficult.

11 Feb 2021

Study provides new insight about integrating treatment for HIV and opioid use disorder in Vietnam

An assessment published this week in the journal The Lancet HIV provides new insight about an initiative to integrate treatment of opioid use disorder along with HIV in Vietnam.

5 Feb 2021

Imaging technique can differentiate Alzheimer's disease from dementia with Lewy bodies

Scientists in Portugal and the United Kingdom were able to confirm that an imaging technique that traces neuronal dopaminergic deficiency in the brain is able to differentiate, in vivo, Alzheimer's disease from lesser-known dementia with Lewy bodies.