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Novel antibiotic shows activity against WHO high priority pathogen VRE

Chemists from the University of Warwick and Monash University have discovered a promising new antibiotic that shows activity against drug-resistant bacterial pathogens, including MRSA and VRE.

27 Oct 2025

Boston Children's Hospital secures $8.1M for spastic paraplegia research

Boston Children's Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., Director of the Movement Disorders Program at Boston Children's, and his team will lead this multi-center effort.

24 Oct 2025

New type of immunotherapy could change the treatment plan for triple-negative breast cancer

Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main targets that make other types of breast cancers more treatable with powerful therapies.

22 Oct 2025

Corneas from diabetic donors perform well in vision restoring surgeries

Many eye banks won't accept corneas from donors with diabetes, concerned they might be harder to prepare for transplant surgery or are more likely to fail.

21 Oct 2025

VICT3R project builds momentum to accelerate animal-free safety testing

The VICT3R project is expanding its consortium by adding new beneficiaries and organisations to the network of contract research organisations (CROs) associated with the project.

16 Oct 2025

Does eating watermelon lower blood pressure?

Researchers reviewed the role of watermelon as a natural source of L-citrulline and its potential to improve cardiovascular health by enhancing nitric oxide production. While promising effects on blood pressure and arterial stiffness were seen in at-risk groups, long-term and dose-specific studies are still needed to confirm clinical benefits.

15 Oct 2025

Unlocking the mysteries of treatment-resistant prostate cancer

Advances in prostate cancer early detection and treatment have improved outcomes in men diagnosed with the disease.

7 Oct 2025

Innovative vibroacoustic sensor could revolutionize eczema and psoriasis treatment

A groundbreaking technology developed by Heriot-Watt University has received over £475,000 in funding to revolutionize how eczema is diagnosed and treated, potentially ending years of suffering for millions of patients across the UK.

2 Oct 2025

Genetic modification enhances "living drugs" for blood cancers

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, with a "chimeric antigen receptor" (CAR) enables them to specifically recognize and attack cancer cells.

25 Sep 2025

CRISPR-based tongue swab test shows promise for tuberculosis detection

Tulane University researchers have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, a potential breakthrough that could allow easier, community-based screenings for the world's deadliest infectious disease.

17 Sep 2025

Why metformin could protect the brain by rewiring mitochondria

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.

1 Sep 2025

Climate variability may speed up the spread of vector-borne diseases

The study reveals that climate variability affects mosquito-borne disease risks, emphasizing the need for improved surveillance and public health strategies.

26 Aug 2025

Sugary drinks increase hair loss risk, scientists warn

A systematic review of 17 studies involving 61,332 participants reveals that vitamin D, iron, and certain foods and supplements play critical roles in hair health. Conversely, sugary drinks, alcohol, and excess vitamin A may worsen hair loss and hair quality.

25 Aug 2025

New drug discovery platform aims to deliver first-in-class therapies

65LAB has awarded US$1.5 million (approx. S$1.9 million) to Professor Enrico Petretto to advance a breakthrough drug discovery platform developed at Duke-NUS Medical School. The project aims to deliver first-in-class antifibrotic therapies for lung and kidney diseases-conditions that currently have no effective treatment.

14 Aug 2025

Old Parkinson's medication offers new hope for tuberculosis treatment

A medication developed in the 1950s to treat Parkinson's disease may offer a powerful new tool in the fight against tuberculosis (TB), according to new research from the University of British Columbia.

12 Aug 2025

Artificial intelligence predicts hospital admissions hours earlier in emergency departments

Artificial intelligence (AI) can help emergency department (ED) teams better anticipate which patients will need hospital admission, hours earlier than is currently possible, according to a multi-hospital study by the Mount Sinai Health System.

11 Aug 2025

UCLA researchers decode the muscle mechanics behind blinking

A blink of an eye seems natural and instantaneous, but is it? Without a functioning eyelid, the eye can become dry, irritated and eventually lose the ability to see clearly.

8 Aug 2025

Wastewater surveillance for detecting COVID-19 offers early warning and cost savings

Wastewater surveillance at treatment plants offers a low-cost, early warning method for detecting COVID-19. Researchers in Japan conducted an economic evaluation of a system for long-term care facilities that combines wastewater data with clinical testing thresholds to guide timely interventions.

30 Jul 2025

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Elenagen™, a novel DNA plasmid therapy that previously demonstrated high clinical benefit and low toxicity in cancer patients, has now shown significant promise in alleviating chronic pain demonstrating a 90% success rate.

23 Jul 2025

Study unveils powerful strategy to rejuvenate effectiveness of CAR T cell therapy against glioblastoma

A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the effectiveness of chimeric antigen receptor (CAR) T cell therapy against glioblastoma, one of the most lethal and treatment-resistant brain tumors.

3 Jul 2025