Craniofacial News and Research

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Researchers uncover role of perivascular cells in blood vessel dysfunction

Researchers at Oregon Health & Science University have uncovered how specialized cells surrounding small blood vessels, known as perivascular cells, contribute to blood vessel dysfunction in chronic diseases such as cancer, diabetes and fibrosis.

13 Jan 2025

Non-opioid pain relief proven more effective after wisdom teeth removal

A combination of acetaminophen (Tylenol) and ibuprofen (Advil, Motrin) controls pain after wisdom tooth removal better than opioids, according to a Rutgers Health study that could change how dentists treat post-surgical pain.

6 Jan 2025

Research highlights inadequate dental benefits in Medicare Advantage

Medicare Advantage - the privatized form of Medicare that offers benefits beyond traditional Medicare, such as dental insurance - is gaining in popularity, but a new analysis reveals that the quality of dental coverage offered by Medicare Advantage is poor, with only 8.4 percent of plans offering a dental benefit that met the study's quality standards.

26 Dec 2024

Researchers discover key genetic mechanism behind craniofacial development

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.

14 Dec 2024

Study identifies potential risk factor for aortic aneurysms in Loeys-Dietz syndrome

Studying the cells of people and genetically engineered mice, Johns Hopkins Medicine scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, are especially prone to developing aneurysms at the root of the aorta, the major artery that carries blood away from the heart and to the rest of the body.

9 Dec 2024

Zebrafish could be used to explore the underlying mechanisms of Nager syndrome

Nager syndrome, or NS, is a rare genetic disease that affects the development of the face and limbs, usually causing anomalies in the bone structures of the jaws, cheeks, and hands.

16 Oct 2024

NIH funding supports investigation of skeletal stem cells in craniofacial bone disorders

Researchers at UTHealth Houston have been awarded an $8.1 million grant by the National Institutes of Health (NIH) to examine skeletal stem cells as potential drivers of craniofacial bone diseases and deformities.

10 Oct 2024

NIH supports research on non-opioid pain relief for oral cancer patients

The School of Dentistry at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) earned the first National Institutes of Health grant under its new Center for Pain Therapeutics and Addiction Research, addressing pain in patients with head and neck carcinoma.

4 Oct 2024

ADA Forsyth Institute secures $6.2 million grant for innovative dental material research

The ADA Forsyth Institute (AFI) has been awarded a $6.2 million grant from the National Institute of Oral and Craniofacial Research (NIDCR). Funded under the highly competitive RM1 mechanism, this five-year award will support a groundbreaking project to develop next-generation smart materials for dental fillings using physics-based artificial intelligence (AI).

30 Sep 2024

Study reveals how chromatin structure influences social behavior in dogs

A new study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior.

14 Aug 2024

Nutrient deprivation drives Klebsiella dominance in hospital settings

Scientists at ADA Forsyth Institute (AFI) have identified a critical factor that may contribute to the spread of hospital-acquired infections (HAIs), shedding light on why these infections are so difficult to combat.

22 Jul 2024

OHStat guidelines emphasize clinically meaningful data in oral health research

The International Association for Dental, Oral, and Craniofacial Research (IADR) and the American Association for Dental, Oral, and Craniofacial Research (AADOCR) have announced the publication of revised guidelines for adequately reporting findings from oral health research. Overviews and explanations of the new guidelines, called the "OHStat Guidelines," will be published in an upcoming issue of Journal of Dental Research as part of a collaborative effort with The Angle Orthodontics, Journal of Endodontics, Journal of the American Dental Association, and Journal of Oral Maxillofacial Surgery. Additionally, a companion paper will be published in an upcoming issue of JDR Clinical & Translational Research.

13 Jul 2024

New drug tirzepatide significantly improves sleep apnea and weight loss

The effects of tirzepatide on adults with obesity and moderate-to-severe obstructive sleep apnea.

26 Jun 2024

Unveiling the heterogeneity of skeletal stem cells across skeletal regions and developmental stages

SSCs are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine.

5 Jun 2024

From ancient remedies to modern medicine: Inorganic materials offer new hope for tissue regeneration

For centuries, civilizations have used naturally occurring, inorganic materials for their perceived healing properties.

31 May 2024

Womb pressure shapes facial features, UCL study reveals

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.

23 Apr 2024

Research offers insights into facial development at the cellular level

Mother Nature is an artist, but her craft of creating animal faces requires more than a paintbrush and palette. Such highly complex shapes originate from their respective transient neural crest cells.

12 Apr 2024

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).

10 Apr 2024

Poor oral health linked to negative long-term systemic health outcomes

Those who report having poor oral health are as likely to have negative long-term systemic health outcomes as those previously diagnosed with periodontal disease, or gum disease, according to a new Tufts University School of Dental Medicine study published in The Journal of the American Dental Association.

8 Apr 2024

The horrors of TMJ: Chronic pain, metal jaws, and futile treatments

A TMJ patient in Maine had six surgeries to replace part or all of the joints of her jaw.

4 Apr 2024