Electrophysiology News and Research

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Electrophysiology-based strategies enhance cancer immunotherapy

Tumor electrophysiological abnormalities, characterized by membrane potential dysregulation, ion channel network remodeling, and microenvironmental signaling interactions, are critical drivers of malignancy.

17 Aug 2025

Community pop-up screenings uncover hidden cardiovascular risk factors

Pop-up screening for atherosclerotic cardiovascular disease (ASCVD) risk held at community pharmacies and large-scale sporting events can identify people with uncontrolled cardiovascular risk factors, according to a study published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at the 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand.

17 Aug 2025

Air purifiers can lower blood pressure in at-risk adults

Using portable high-efficiency particulate air (HEPA) purifiers at home can significantly lower systolic blood pressure (SBP) in adults with elevated baseline readings — even in areas with relatively low overall air pollution levels, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

6 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025

High-performance computing sheds light on heart rhythm disorders

You may have heard the phrase "my heart skipped a beat" when someone was talking about a romantic encounter.

31 Jul 2025

Thalamic feedback pathway found to tune sensory perception

The cerebral cortex processes sensory information via a complex network of neural connections. How are these signals modulated to refine perception? A team from the University of Geneva (UNIGE) has identified a mechanism by which certain thalamic projections target neurons and modify their excitability.

30 Jul 2025

Mexican neuroscientist's journey from exile to schizophrenia research breakthroughs

In a revealing Genomic Press Interview published today in Brain Medicine, Dr. Camilo de la Fuente-Sandoval shares how personal history and scientific passion converged to create groundbreaking advances in schizophrenia treatment prediction.

29 Jul 2025

Gut bacteria send direct signals to the brain to stop you from overeating

Researchers have discovered a novel gut-brain sensory circuit in mice where specialized colonic cells sense bacterial flagellin and rapidly suppress feeding via the vagus nerve. This "neurobiotic sense" operates independently of immune pathways, revealing a direct neural mechanism for microbiota-host communication.

24 Jul 2025

How can super-resolution technology help study neurotransmission?

Discover how super-resolution technology can be used to sudy neurotransmission at inhibitory synapses.

From Bruker Nano Surfaces and Metrology 17 Jul 2025

Wildfire smoke exposure linked to increased heart failure risk

Long-term exposure to wildfire smoke may increase the risk of heart failure (HF), especially in older adults, women and vulnerable populations, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

23 Jun 2025

New brain study explains why some pain becomes chronic

A new study reveals that when we experience short-term (acute) pain, the brain has a built-in way to dial down pain signals - like pressing the brakes - to keep them from going into overdrive.

20 Jun 2025

New ACC guidance helps incorporate pharmacologic weight management strategies into cardiovascular care

The American College of Cardiology has issued a Concise Clinical Guidance (CCG) document to aid clinicians in the use of medication for weight management in patients where treatment may provide cardiovascular benefit.

20 Jun 2025

Breakthrough microimager offers new possibilities for internal imaging

Researchers have developed an extremely thin, flexible imager that could be useful for noninvasively acquiring images from inside the body. The new technology could one day enable early and precise disease detection, providing critical insights to guide timely and effective treatment.

19 May 2025

Microscopic structural changes in the aging heart may reduce risk of arrhythmias

Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC have discovered that microscopic structural changes in the aging heart may reduce the risk of irregular heartbeats.

19 May 2025

Study sheds light on why women have faster heartbeats than men

For decades, doctors and researchers have puzzled over a basic heart rhythm mystery: Why do women tend to have faster heartbeats while men are more likely to develop irregular rhythms like atrial fibrillation (AFib)?

15 May 2025

Sumeet Chugh named vice dean and chief artificial intelligence health research officer at Cedars-Sinai

Sumeet Chugh, MD, whose research into sudden cardiac arrest has led to novel methods of predicting the usually fatal condition, has been promoted to vice dean and chief artificial intelligence health research officer at Cedars-Sinai.

11 May 2025

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Metrion Biosciences ("Metrion"), the specialist preclinical contract research organization (CRO) and a global leader in ion channel services, today announced the launch of its validated, high-throughput NaV1.9 screening assay to advance discovery and development of novel pain therapeutics.

28 Apr 2025

Study illuminates a general principle of neural processing in the brain’s serotonin system

Our lives are filled with binary decisions – choices between one of two alternatives. But what's really happening inside our brains when we engage in this kind of decision making?

25 Apr 2025

Mount Sinai researchers enhance AI tool to better detect heart disease risk

Mount Sinai researchers studying a type of heart disease known as hypertrophic cardiomyopathy (HCM) have calibrated an artificial intelligence (AI) algorithm to quickly and more specifically identify patients with the condition and flag them as high risk for greater attention during doctor's appointments.

22 Apr 2025

Mount Sinai Fuster Heart Hospital earns national recognition for patient care excellence

The Mount Sinai Fuster Heart Hospital's cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, one of the nation's leading patient experience organizations.

16 Apr 2025