Encephalopathy News and Research

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Study links combined risk factors for aggressive behavior in men with CTE

People who have chronic traumatic encephalopathy (CTE) who have a family history of mental illness may have a higher risk of aggression in middle age, according to a study published in the November 27, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

27 Nov 2024

Soccer heading may cause long-term brain damage

Soccer heading may cause more damage to the brain than previously thought, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2024

Innovative tool enhances the accuracy of predicting survival outcomes for liver failure patients

Researchers have unveiled a groundbreaking advancement in liver failure care: the CATCH-LIFE-MELD score (Chinese Acute-on-Chronic Liver Failure Consortium (CATCH-LIFE)-MELD score).

26 Nov 2024

Review: The multifaceted roles of bilirubin in liver health and disease

Bilirubin, the byproduct of hemoprotein breakdown, particularly hemoglobin, is a critical marker in diagnosing, prognosing, and managing liver diseases.

6 Nov 2024

Researchers uncover the hidden history of concussion in sports

University of Queensland researchers have uncovered the hidden history of concussion in sport, finding the brain-trauma crisis has a long and complex past.

4 Nov 2024

New study identifies potential treatment for tauopathies using carbonic anhydrase inhibitors

Carbonic anhydrase inhibitors show potential in reducing tau protein buildup, offering new therapeutic avenues for neurodegenerative diseases like tauopathies.

4 Nov 2024

Carbonic anhydrase inhibitors clear tau build-up in zebrafish models of tauopathies

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is implicated in Alzheimer’s disease.

4 Nov 2024

Glaucoma medication may help prevent Alzheimer's-related tau build-up

1 Nov 2024

Ratiometric fluorescent probes for measuring active albumin in liver disease patients

Albumin is a major prognostic factor for patients with advanced liver disease, dependent on its concentration and biological activity.

29 Oct 2024

New study reveals long-term brainstem damage in COVID-19 survivors using advanced MRI scans

A study using 7T QSM identifies microstructural changes in the brainstem of COVID-19 survivors, suggesting links to long-term neuroinflammatory responses.

10 Oct 2024

Understanding the role of TIPS in improving renal function amid cirrhosis

Cirrhosis is one of the leading causes of mortality from non-communicable diseases, with complications arising as liver function deteriorates.

26 Sep 2024

COVID-19 causes lasting cognitive impairment tied to brain injury markers

Researchers found that COVID-19 patients experienced widespread cognitive deficits one year post-hospitalization, associated with elevated brain injury markers and reduced brain volume. Cognitive recovery plateaued over time, suggesting lasting impacts.

26 Sep 2024

One-third of former professional American football players report a punch-drunk reality - CTE

Study found that one-third of former American football players reported perceived CTE, which was significantly associated with a higher risk of suicidality and mental health problems.

25 Sep 2024

Speech analysis phone app could identify early signs of hepatic encephalopathy

Research from the University of Michigan suggests that one day a phone app could be able to detect the development of hepatic encephalopathy in patients just by listening to them speak.

18 Sep 2024

Study unveils potential treatment for chronic brain damage following traumatic injury

Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with chronic neurodegeneration and related impairments due to TBI.

11 Sep 2024

American football head impacts tied to increased brain damage and cognitive decline

Repetitive head impacts in former American football players are linked to increased perivascular space volume, which correlates with cognitive decline and neurodegeneration. The study suggests that the force of head impacts may be more critical than frequency, with potential protective effects from β-blocker use.

1 Sep 2024

Study identifies genetic cause of severe seizures in children

Shortly after Kelly Cervantes' daughter Adelaide was born, she started having terrible seizures. Doctors were unable to give her a solution, or even a cause.

28 Aug 2024

New compound shows promise in Alzheimer’s preclinical models

A multidisciplinary team of scientists led by Kurt Brunden, Ph.D., at the University of Pennsylvania Perelman School of Medicine, and Carlo Ballatore, Ph.D., at University of California San Diego, has been awarded a $6.9 million grant from the National Institute on Aging (NIA) to prepare a potential disease-modifying Alzheimer's treatment for future clinical trials.

21 Aug 2024

NIH awards $6.9 million to prepare a potential Alzheimer's treatment for future clinical trials

A multidisciplinary team of scientists led by Carlo Ballatore, Ph.D., at University of California San Diego and Kurt Brunden, Ph.D., at the University of Pennsylvania has been awarded a $6.9 million grant from the National Institute on Aging (NIA) to prepare a potential disease-modifying Alzheimer's treatment for future clinical trials.

20 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

Encephalopathy News and Research

Study links combined risk factors for aggressive behavior in men with CTE

Soccer heading may cause long-term brain damage

Innovative tool enhances the accuracy of predicting survival outcomes for liver failure patients

Review: The multifaceted roles of bilirubin in liver health and disease

Researchers uncover the hidden history of concussion in sports

New study identifies potential treatment for tauopathies using carbonic anhydrase inhibitors

Carbonic anhydrase inhibitors clear tau build-up in zebrafish models of tauopathies

Glaucoma medication may help prevent Alzheimer's-related tau build-up

Ratiometric fluorescent probes for measuring active albumin in liver disease patients

New study reveals long-term brainstem damage in COVID-19 survivors using advanced MRI scans

Understanding the role of TIPS in improving renal function amid cirrhosis

COVID-19 causes lasting cognitive impairment tied to brain injury markers

One-third of former professional American football players report a punch-drunk reality - CTE

Speech analysis phone app could identify early signs of hepatic encephalopathy

Study unveils potential treatment for chronic brain damage following traumatic injury

American football head impacts tied to increased brain damage and cognitive decline

Study identifies genetic cause of severe seizures in children

New compound shows promise in Alzheimer’s preclinical models

NIH awards $6.9 million to prepare a potential Alzheimer's treatment for future clinical trials

Study advances understanding of complex neurological disorder

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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