Exosome News and Research

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MCG scientists report how exercise can counter the damage of diabetes

One way exercise can counter the damage of diabetes is by enabling activation of a natural system we have to grow new blood vessels when existing ones are ravaged by this disease, scientists report.

26 Apr 2022

Cells’ exosomes can be effective vehicles for delivering cancer treatments to tumors

A new study published in Cancer Medicine indicates that exosomes, or small bubbles that transport molecules from one cell to another, can be effective vehicles for delivering cancer treatments to tumors.

20 Apr 2022

Novel strategy can shrink tumors and prolong survival in mice

A research team based at the University of Ottawa and The Ottawa Hospital has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attack.

11 Apr 2022

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Researchers evaluate antiviral effects of CD63 tetraspanin extracellular vesicles against SARS-CoV-2 and HIV-1.

22 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Scientists identify new biomarkers that can be used as predictive tools of deep space flight risks

An international team of scientists has found new biomarkers that can be used for diagnostic purposes and potentially as predictive tools of the risks associated with deep space flight.

2 Mar 2022

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Codiak BioSciences, Inc., a clinical-stage biopharmaceutical company pioneering the development of exosome-based therapeutics as a new class of medicines, today announced the online publication of a new manuscript, Exosome mediated genetic reprogramming of tumor associated macrophages by exoASO-STAT6 leads to potent monotherapy anti-tumor efficacy, in the American Association for the Advancement of Science's journal, Science Advances.

18 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Study sheds light on how melanoma primes nearby lymph nodes for tumor metastases

Melanoma cells release small extracellular packages containing the protein nerve growth factor receptor, which primes nearby lymph nodes for tumor metastases, according to a new study by Weill Cornell Medicine investigators.

21 Jan 2022

SARS-CoV-2 infection and immunity in pregnancy and fetal development

A review conducted by a team of researchers from the Icahn School of Medicine at Mount Sinai, the University of Colorado, and Active Motif, Incorporated compiles information on SARS-CoV-2 virology, in utero transmission from infected pregnant mothers to fetuses, new findings on possible methods of SARS-CoV-2 cellular trafficking through exosomes, and the transcriptomic effects of SARS-CoV-2 infection, in order to inform future studies aimed at a better understanding of COVID-19 and the development of therapeutic solutions against SARS-CoV-2.

30 Dec 2021

Defensosomes can act as decoys to protect against SARS-CoV-2

In a new study, researchers from New York University have been examining the ability of defensosomes to combat SARS-CoV-2 infection.

22 Dec 2021

Research reveals nucleolar RNA interference based on C. elegans as a model organism

A research group led by Prof. GUANG Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. FENG Xuezhu from the First Affiliated Hospital of USTC, revealed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism. The study was published in Nuclear Acids Research.

28 Sep 2021

Study paves the way for development of novel delivery systems to suppress HIV

In a new study supported by the National Institutes of Health, researchers used exosomes, tiny nanoparticles capable of being taken up by cells, to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs' genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.

21 Sep 2021

UH associate professor receives $2.5 million to explore how arterial hardening starts within cells

In diseases such as hypertension, aging, atherosclerosis, diabetes and chronic kidney disease, arterial calcification and stiffening of the elastic layer of the arterial wall are almost always present.

30 Aug 2021

Scientists develop a scalable method to harvest exosomes from unpasteurized cow's milk

Exosomes are nano-sized biological capsules that cells produce to protect and courier delicate molecules throughout the body.

23 Aug 2021

Biotium releases new ExoBrite EV Membrane Staining Kits

Biotium, a leading supplier and inventor of fluorescent cellular probes for life science research, announces the release of new ExoBrite™ EV Membrane Staining Kits.

17 Aug 2021

Highly Efficient Exosome Isolation & Purification Tools

AMSBIO is a knowledgeable supplier of products dedicated to exosome research that includes high quality reagents and kits that are quick, affordable and easy to use.

From AMS Biotechnology 1 Aug 2021

Simple method to assess the risk of vascular inflammation for diabetes patients

A team of international scientists from Nanyang Technological University, Singapore (NTU Singapore), Tan Tock Seng Hospital (TTSH) in Singapore, and the Massachusetts Institute of Technology (MIT) has developed a simple method of extracting tiny biological particles from a person's blood and use them as biomarkers to assess the health of their blood vessels.

27 Jul 2021

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

26 Jul 2021

UH researcher receives $2.7 million grant to detect cancer biomarkers in blood by counting exosomes

University of Houston engineering researcher Wei-Chuan Shih has been awarded $2.7 million from the National Institute of Biomedical Imaging and Bioengineering to detect cancer biomarkers in blood by counting exosomes.

20 Jul 2021