Glucose News and Research

RSS

Artificial sweetener xylitol associated with higher risk of adverse cardiovascular events

A study to be presented at ESC Congress 2026 will show that high blood levels of the artificial sweetener, xylitol, were associated with increased risk of major adverse cardiovascular events.

26 Aug 2026

Maternal obesity alters fetal liver metabolism via placental molecular signals

A mother's obesity during pregnancy may send molecular signals across the placenta that permanently alter her son's liver metabolism, according to a new study in mice published in Nature Communications.

26 Aug 2026

GLP-1 drugs may reshape obesity care, but clinicians still have questions

Interviews with 11 healthcare professionals in a UK specialist weight management service found generally positive attitudes toward injectable GLP-1 drugs, alongside limited formal training and uncertainty about how the medications should be integrated with behavioral care. Participants anticipated potential benefits for confidence and weight management but also raised concerns about treatment discontinuation, behavioral engagement, and evolving professional responsibilities.

26 Aug 2026

A year after women lost weight, researchers saw which health gains lasted and which faded

Diet-induced weight loss significantly reduced predicted 10-year risks of major adverse cardiovascular events and type 2 diabetes in healthy premenopausal women with overweight, regardless of whether aerobic or resistance exercise was added. Some of these gains diminished as weight was partially regained over the following year, although greater exercise adherence was associated with less rebound in predicted diabetes risk.

25 Aug 2026

Diabetes study reveals differing health risks for men and women

In the years following type 2 diabetes diagnosis, women are more likely to develop mental health conditions, while men are more likely to develop cardiovascular and renal complications, according to a study published August 25th in the open access journal PLOS Medicine by Fabiola Eto from Queen Mary University of London, UK, and colleagues.

25 Aug 2026

What decades of wine research can, and cannot, tell us about health

A narrative review found that moderate wine intake has repeatedly been associated with lower all-cause and cardiovascular mortality, with proposed mechanisms involving ethanol and grape-derived polyphenols, but the evidence remains largely observational and cannot establish causation. The authors argue that drinking pattern, beverage type, age, cancer risk, and risk-modeling choices all influence how the J-shaped association should be interpreted and how alcohol guidelines are developed.

25 Aug 2026

From caffeine to trigonelline, coffee has surprising links to muscle biology

A scoping review of 54 studies found that coffee and several coffee-derived bioactive compounds influence pathways linked to skeletal muscle metabolism, including insulin signaling, mitochondrial function, oxidative stress, inflammation, glucose uptake, and protein turnover. Human studies reported associations with greater muscle mass and lower frailty or functional impairment, but most evidence remains observational or preclinical and cannot establish causality.

25 Aug 2026

Scientists compared 51 longevity studies to see which aging biomarkers respond most reliably

Researchers analyzing 51 longitudinal intervention studies found that reliable generation 2+ DNA methylation biomarkers, particularly those predicting mortality or pace of aging, were the most responsive to interventions aimed at longevity or healthspan. Pharmacological and lifestyle interventions produced the strongest biomarker changes, but the authors cautioned that responsiveness does not yet establish these measures as validated surrogate endpoints for slower aging or longer life.

25 Aug 2026

Researchers link GLP-1 drugs to lower tuberculosis risk in type 2 diabetes

A large retrospective cohort study found that GLP-1 receptor agonist use was associated with a lower risk of tuberculosis in people with type 2 diabetes compared with sulfonylureas, metformin, DPP-4 inhibitors, and SGLT2 inhibitors. The observational findings suggest a possible benefit beyond metabolic control, but the authors emphasize that prospective and mechanistic studies are needed to determine whether GLP-1 therapies themselves reduce TB risk.

24 Aug 2026

UC Berkeley researchers find new potential treatment for obesity and diabetes

Over the past five years, medications called GLP-1s have revolutionized the treatment of metabolic disorders like obesity, diabetes and fatty liver diseases.

21 Aug 2026

Study provides a more nuanced picture of biological mechanisms linked to autism

How does autism manifest in the brain? Researchers from the University of Southern Denmark and Odense University Hospital have investigated this question in a new study involving 60 adults.

21 Aug 2026

Review outlines how SIRT3 protein regulates global metabolic disorders

A comprehensive review published in Engineering systematically outlines the regulatory capacity of silent information regulator 3 (SIRT3), a mitochondrial deacetylase termed the "head goose molecule", and its negentropic mechanism for intervening global metabolic disorders including type 2 diabetes, obesity, and steatotic liver disease.

21 Aug 2026

Sprinters and non-athletes had similar gut diversity, but one key difference emerged

College sprint athletes showed a distinct gut microbial community structure, including higher abundance of Segatella copri and Bifidobacterium adolescentis, compared with non-athletic students. Their microbiomes also showed predicted enrichment of carbohydrate and amino acid metabolism pathways, while exploratory analyses linked several dietary factors with the signature bacteria.

20 Aug 2026

More coffee, higher testosterone? This study found a more complicated picture

Higher habitual coffee intake was associated with a leaner body composition, lower circulating branched-chain amino acids, and distinct cardiometabolic patterns in 2,264 middle-aged Finnish adults. Hormonal associations differed by sex, with broader testosterone- and SHBG-related patterns in men and more limited SHBG-related changes in women.

20 Aug 2026

Gene editing fails to protect beta-cell transplants from rejection

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

19 Aug 2026

Global study reveals rising chronic kidney disease burden in women

Chronic kidney disease is now the seventh leading cause of death among noncommunicable diseases globally, affecting 11–13% of the adult population.

19 Aug 2026

Researchers put olive and fish oil IV nutrition under the microscope

A systematic review of six randomized trials compared olive-oil-based and fish-oil-containing parenteral nutrition in hospitalized adults, examining infection, inflammation, oxidative stress, liver function, and clinical outcomes. The included studies involved diverse patient groups and lipid formulations, with substantial variation in outcomes and insufficient evidence for a meta-analysis.

18 Aug 2026

Women with type 2 diabetes saw striking changes after 24 weeks of this eating pattern

A 24-week randomized trial found that a lacto-vegetarian diet combined with 14-hour time-restricted eating improved glycemic control, insulin resistance, body weight, and lipid measures in Indian women with type 2 diabetes. The combined, nutritionist-supported intervention was generally well tolerated, but its individual dietary and fasting effects cannot be separated and longer-term studies are needed.

18 Aug 2026

UToledo researchers find new way to spot earliest warning signs of liver disease

Liver disease often progresses silently until it has become a serious condition. Researchers at The University of Toledo may have found a way to identify one of its earliest warning signs before symptoms appear.

18 Aug 2026

Whole grains, legumes and vegetables stand out in a major review of diabetes diets

Healthy plant-based diets rich in whole grains, legumes, fruits, vegetables, nuts, and seeds are associated with better glycemic control and a lower risk of type 2 diabetes. The review finds that food quality and processing matter more than simply avoiding animal foods, while unhealthy plant-based patterns and higher red and processed meat intake are associated with greater metabolic risk.

18 Aug 2026