Head and Neck Cancer News and Research

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Head and Neck Cancer is cancer that arises in the head or neck region (in the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx [voice box]).

Air pollution linked to head and neck cancer risk

Increased PM2.5 levels are linked to higher head and neck cancer risk, particularly in disadvantaged communities, highlighting urgent public health measures.

15 Nov 2024

Air pollution found to contribute to head and neck cancer incidence

A recent study published in the journal Scientific Reports correlates higher levels of pollutant particulate matter to higher occurrences of head and neck aerodigestive cancer.

12 Nov 2024

New approach reinvigorates exhausted T cells to improve tumor control

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells - which have lost their cancer-fighting oomph - consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and UPMC Hillman Cancer Center.

8 Nov 2024

New imaging technique enhances tumor and nerve visualization in HNSCC surgery

Head and neck squamous cell carcinoma (HNSCC) ranks as one of the most common cancers globally, with over 650,000 new cases reported each year.

7 Nov 2024

Efforts to increase diversity in cancer clinical trials fall short

In the U.S., millions of people experience cancer every year but don't have an equal opportunity to access experimental treatments in clinical trials, or to receive treatments that were shown to be effective in patients like them.

15 Oct 2024

Standard chemoradiation outperforms de-intensified treatments in HPV-associated oropharyngeal cancer

Researchers looking to de-intensify radiation treatments for people with early-stage, HPV-associated oropharyngeal cancer to prevent long-term side effects halted a large, randomized phase II/III trial after patients in the control arm reached a record high, two-year progression-free survival rate of 98%.

30 Sep 2024

Study offers new insight into the link between oral microbiome and head and neck cancers

More than a dozen bacterial species among the hundreds that live in people's mouths have been linked to a collective 50% increased chance of developing head and neck squamous cell carcinoma (HNSCC), a new study shows.

26 Sep 2024

Pre-surgery chemotherapy shows promise for preserving vital organs in nasal and sinus cancer

Results from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received chemotherapy before surgery to remove advanced squamous cell-type cancer of the nose or sinus.

11 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

Saliva test offers hope for head and neck cancer patients

But what if a mouthwash-based test to detect biomarkers can help physicians predict disease recurrence in head and neck cancer patients?

16 Aug 2024

Does cannabis use disorder increase the risk of head and neck cancer?

Researchers determine whether cannabis use disorder increases the risk of head and neck cancer.

12 Aug 2024

Cannabis dependence associated with increased occurrence of head and neck cancer

A study from the USC Head and Neck Center, part of Keck Medicine of USC and the USC Caruso Department of Otolaryngology – Head and Neck Surgery, suggests that cannabis, the most commonly used illicit substance worldwide, is associated with an increased occurrence of head and neck cancer.

8 Aug 2024

New dual kinase inhibitor MTX-531 shows promise in overcoming cancer therapy resistance

A team of researchers at the University of Michigan Health Rogel Cancer Center has designed a molecule that impairs signaling mediated by two key drivers of cancer therapy resistance.

29 Jul 2024

Researchers develop advanced method to analyze liquid biopsies of DNA fragments in the blood

Oncologists use biopsy and imaging techniques to diagnose and monitor tumor diseases and assess treatment success.

1 Jul 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

Revolutionary AI tool detects multiple cancers in whole-body PET/CT scans

A novel AI approach can accurately detect six different types of cancer on whole-body PET/CT scans, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.

11 Jun 2024

Do taste genes influence how much alcohol we drink and our body fat?

Study examines how polymorphisms in bitter taste receptor genes relate to alcohol consumption and body fat percentage, revealing significant associations with TAS2R13 but not TAS2R38.

9 Jun 2024

Phase III trial highlights benefits of intensity modulated proton therapy for oropharyngeal cancer

According to preliminary data from a multi-institution Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, intensity modulated proton therapy (IMPT) achieved similar clinical outcomes and offered significant patient benefits when compared to traditional intensity modulated radiation therapy (IMRT) as part of chemoradiation treatment for patients with oropharyngeal (head and neck) cancer.

6 Jun 2024

UCSF to lead first long-term study of cancer among Asian Americans

UC San Francisco researchers have received $12.45 million from the National Cancer Institute (NCI) to lead the first long-term study of cancer among Asian Americans, a highly diverse yet understudied group.

22 May 2024

Urine-based test developed for early detection of head and neck tumors

Researchers from the University of Michigan Health Rogel Cancer Center have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors.

16 Apr 2024