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MRI measures of glymphatic activity may improve noninvasive intracranial hypertension diagnosis

A new study led by investigators from Mass General Brigham shows that a brain waste- "clean-up" system is influenced by intracranial pressure.

27 Jan 2026

Low patient engagement hinders at-home blood pressure management

Despite guideline recommendations and improved access to care, individuals with hypertension are unlikely to measure their blood pressure at home as often as recommended, according to data from researchers at Mass General Brigham.

21 Jan 2026

Bio-engineered skin grafts offer new hope for severe burn injuries

Bio-engineered skin grafts can play an important role in the treatment of burn victims. Researchers at the University of Zurich have been working on new approaches for such grafts for over 15 years.

15 Jan 2026

Autonomous AI system screens for cognitive impairment using routine clinical notes

A team of Mass General Brigham researchers has developed one of the first fully autonomous artificial intelligence (AI) systems capable of screening for cognitive impairment using routine clinical documentation.

15 Jan 2026

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting response to a newly approved immunotherapy called tarlatamab.

14 Jan 2026

New metabolomic signature predicts type 2 diabetes risk beyond traditional factors

Diabetes, a metabolic disease, is on the rise worldwide, and over 90 percent of cases are type 2 diabetes, where the body does not effectively respond to insulin.

14 Jan 2026

Resistance to rezatapopt: New TP53 mutations identified in cancer patients

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics.

12 Jan 2026

Global analysis shows widespread eligibility for GLP-1 weight management drugs

The worldwide prevalence of obesity has more than doubled in the last three decades, bringing with it an increase in weight-related diseases like diabetes, cardiovascular disease, and cancers.

8 Jan 2026

Solving the home care quandary

You're ready to leave the hospital, but you don't feel able to care for yourself at home yet.

8 Jan 2026

Single-dose oral cholera vaccine shows promising results in early clinical trial

Clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide.

7 Jan 2026

Economic instability linked to higher risk of long COVID in children

New research led by Mass General Brigham investigators suggests that long COVID is more prevalent in school-aged children and adolescents who experience economic instability and adverse social conditions.

5 Jan 2026

Artificial intelligence improves risk stratification in oropharyngeal cancer

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient's oropharyngeal cancer-a type of head and neck cancer that develops in the throat-will spread, thereby signaling which patients should receive aggressive treatment.

23 Dec 2025

Early brain connectivity predicts recovery after traumatic brain injury

After traumatic brain injury (TBI), some patients may recover completely, while others retain severe disabilities.

22 Dec 2025

Rethinking Mendelian assumptions in inherited retinal degenerations

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

22 Dec 2025

Study finds Brain Care Score as a strong predictor of stroke across racial groups

A new study from Mass General Brigham found the Brain Care Score (BCS) is a strong predictor of stroke across different racial groups in the U.S.

18 Dec 2025

Stress may help explain why patients with depression are at higher risk of cardiovascular disease

Patients with depression are at higher risk of cardiovascular disease, and a new study suggests that stress may help explain why.

17 Dec 2025

Hyperphosphorylated tau may help protect the brain from infection

One of the main proteins that contributes to Alzheimer's disease is called phospho-tau (p-tau). When p-tau gets too many phosphate groups attached to it (a process called hyperphosphorylation), it starts to stick together and form clumps called "tangles" inside of brain nerve cells.

17 Dec 2025

Immune checkpoint inhibitors can trigger rare immune thrombocytopenia in cancer patients

Researchers led by investigators at Mass General Brigham have published valuable information about a rare but serious complication of anti-cancer immunotherapy, providing the first large-scale description of its risk factors and clinical course, and underscoring the importance of early diagnosis and treatment.

12 Dec 2025

Early relapse predicts poor survival in mature nodal T-cell lymphoma

Mature nodal T-cell lymphoma is a type of rare and aggressive blood cancer. Limited data make it difficult to identify high-risk patients or tailor treatment strategies, so most patients receive similar care despite differences in disease characteristics and outcomes.

12 Dec 2025

Mass General Brigham launches AI company to enhance clinical trial matching

Mass General Brigham is announcing the spinout of AIwithCare, a company founded by researchers from the health system who developed an artificial intelligence (AI) screening tool that significantly outperformed manual screening for determining a patient's eligibility and enrolling them in a clinical trial.

12 Dec 2025

Home Care News and Research

MRI measures of glymphatic activity may improve noninvasive intracranial hypertension diagnosis

Low patient engagement hinders at-home blood pressure management

Bio-engineered skin grafts offer new hope for severe burn injuries

Autonomous AI system screens for cognitive impairment using routine clinical notes

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

New metabolomic signature predicts type 2 diabetes risk beyond traditional factors

Resistance to rezatapopt: New TP53 mutations identified in cancer patients

Global analysis shows widespread eligibility for GLP-1 weight management drugs

Solving the home care quandary

Single-dose oral cholera vaccine shows promising results in early clinical trial

Economic instability linked to higher risk of long COVID in children

Artificial intelligence improves risk stratification in oropharyngeal cancer

Early brain connectivity predicts recovery after traumatic brain injury

Rethinking Mendelian assumptions in inherited retinal degenerations

Study finds Brain Care Score as a strong predictor of stroke across racial groups

Stress may help explain why patients with depression are at higher risk of cardiovascular disease

Hyperphosphorylated tau may help protect the brain from infection

Immune checkpoint inhibitors can trigger rare immune thrombocytopenia in cancer patients

Early relapse predicts poor survival in mature nodal T-cell lymphoma

Mass General Brigham launches AI company to enhance clinical trial matching

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