Interstitial Lung Disease News and Research

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Interstitial lung disease (ILD) is a broad group of lung diseases comprising of more than a hundred distinct disorders. All of these involve scarring or inflammation of the interstitial lung tissue and affect the volume of oxygen that can reach the bloodstream via the respiratory system.

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

Researchers identified risk factors for and the prevalence of persistent pulmonary tissue alterations among hospitalized coronavirus disease 2019 (COVID-19) patients.

7 Dec 2022

Study assesses the prevalence of residual lung abnormalities following COVID-19 hospitalization

In a new study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, researchers sought to determine the percentage of COVID-19 patients discharged from the hospital who had a type of fibrotic lung damage, known as interstitial lung disease, that requires ongoing follow-up care.

2 Dec 2022

Study links chemical composition of fine particulate air pollution to worse lung disease outcomes

People with a disease characterized by lung scarring that has no obvious cause are more likely to die if they live in areas with higher levels of air pollution composed of chemicals associated with industrial sources and vehicular traffic, according to new research led by University of Pittsburgh scientists.

17 Oct 2022

Multiple ischemic strokes and pulmonary embolism found in COVID-19 patient

In a new study, researchers described a case of a patient with acute respiratory failure and ischemic stroke.

17 Oct 2022

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

New screening tool accurately identifies patients at high risk of idiopathic pulmonary fibrosis

A new screening tool for electronic medical records accurately identifies patients who are at high risk of having or developing progressive scarring of the lungs, a condition called idiopathic pulmonary fibrosis, according to investigators from Weill Cornell Medicine, NewYork-Presbyterian, the University of Chicago, Brigham and Women's Hospital and Mayo Clinic.

29 Sep 2022

Anti-fibrotics found to be safe, effective for interstitial lung disease in patients with rheumatoid arthritis

For the first time, researchers have shown that a class of anti-fibrotic drugs slows the progression of interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA).

22 Sep 2022

New white paper outlines the issues surrounding delays in diagnosing interstitial lung diseases

A steering committee of pulmonary experts and primary care physicians (PCPs) released today a white paper outlining the issues surrounding delays in diagnosing interstitial lung diseases (ILDs) like pulmonary fibrosis (PF).

19 Sep 2022

Study offers insight into the basic cellular pathologies driving interstitial lung disease

While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection.

21 Jul 2022

COVID-19 outcomes improved for SARDs patients through Omicron wave

In a recent study posted to the medRxiv* pre-print server, researchers investigated coronavirus disease 2019 (COVID-19) incidence and severity among systemic autoimmune rheumatic diseases (SARDs) patients in Massachusetts, United States (US), between March 1, 2020, and January 31, 2022.

22 Jun 2022

Pulmonary and primary care experts aim to reduce the time to diagnose interstitial lung diseases

The American College of Chest Physicians (CHEST) and Three Lakes Foundation are announcing a steering committee of experts in the fields of pulmonary medicine and primary care medicine to lead an initiative called Bridging Specialties™: Timely Diagnosis for ILD Patients.

9 Jun 2022

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

A new study discusses the outcomes of idiopathic pulmonary fibrosis patients with confirmed SARS-CoV-2 infection.

6 Mar 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

A commercial-stage company focused on generating data-driven insights to diagnose, understand and treat rare diseases, and Insilico Medicine, an end-to-end Artificial Intelligence (AI) - driven drug discovery company, today announced a research and development collaboration to accelerate the discovery of novel therapeutic targets for Niemann-Pick disease type C

21 Jan 2022

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

The LIVE-AIR phase 3 clinical trial is associated with early treatment of hyperinflammatory response with the humanized monoclonal antibody lenzilumab in COVID-19 patients with decreased oxygen saturation. The study results are posted to the medRxiv* preprint server.

6 Jan 2022

Correlation between idiopathic pulmonary fibrosis and COVID-19

A new study investigates the genetic overlap between COVID-19 and idiopathic pulmonary fibrosis to identify possible shared biological mechanisms.

14 Dec 2021

Black patients with systemic sclerosis may experience poorer outcomes more often than others

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that Black people living with systemic sclerosis may have more severe disease and worse prognosis than patients in other racial or ethnic groups, and these worrying disparities may be driven by several socioeconomic factors.

2 Nov 2021

Teen’s mysterious condition spurs the opening of Childhood Interstitial Lung Disease Clinic

Thirteen-year-old Gregory Rhoden's condition has been a mystery his entire life. He was born prematurely and his lungs seemed underdeveloped.

7 Oct 2021

New study aims to find early drivers of pulmonary fibrosis in at-risk patient population

Researchers at Vanderbilt University Medical Center are leading a study designed to identify early drivers of pulmonary fibrosis in an at-risk patient population. Funding for the research, which could help predict early disease at the cellular level and possibly drive the development of novel therapies, is being provided by Three Lakes Foundation.

6 Oct 2021

Interstitial Lung Disease News and Research

Further Reading

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

Study assesses the prevalence of residual lung abnormalities following COVID-19 hospitalization

Study links chemical composition of fine particulate air pollution to worse lung disease outcomes

Multiple ischemic strokes and pulmonary embolism found in COVID-19 patient

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

New screening tool accurately identifies patients at high risk of idiopathic pulmonary fibrosis

Anti-fibrotics found to be safe, effective for interstitial lung disease in patients with rheumatoid arthritis

New white paper outlines the issues surrounding delays in diagnosing interstitial lung diseases

Study offers insight into the basic cellular pathologies driving interstitial lung disease

COVID-19 outcomes improved for SARDs patients through Omicron wave

Pulmonary and primary care experts aim to reduce the time to diagnose interstitial lung diseases

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Researchers identify genetic cause of rare interstitial lung disease in a young child

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

Correlation between idiopathic pulmonary fibrosis and COVID-19

Black patients with systemic sclerosis may experience poorer outcomes more often than others

Teen’s mysterious condition spurs the opening of Childhood Interstitial Lung Disease Clinic

New study aims to find early drivers of pulmonary fibrosis in at-risk patient population

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