Lyophilization News and Research

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Freeze-drying, also referred to as lyophilization, is a process that involves freezing a substance at very low temperatures and then extracting liquid via sublimation, converting water from a solid to gaseous state.

Praxair China installs NCOOL system at Shanghai Pharmaceutical

Praxair China has installed its NCOOL™ cryogenic heat exchanger system at Shanghai The First Biochemical & Pharmaceutical Co., Ltd., an affiliate of Shanghai Pharmaceutical (Group) Ltd. This is the first liquid nitrogen supply contract that Praxair China has signed that employs Praxair’s patented NCOOL cryogenic heat exchanger system in a pharmaceutical freeze dryer.

21 Sep 2009

EnWave signs Confidentiality Agreements with food production companies

EnWave Corporation (TSX VENTURE:ENW)(FRANKFURT:E4U) ("EnWave" or "the Company") today announced that it has signed Confidentiality Agreements with more than 15 food production companies located in North and South America, Europe and Korea to determine the benefits of using its nutraREVTM food dehydration technology in a wide range of new product areas including herbs, mushrooms, bananas, mangos, pineapples, peppers, tomatoes, garlic, snack chips, shrimp, salmon and pet treats.

17 Sep 2009

Bavarian Nordic begins negotiations with U.S. to secure a contract to develop a freeze-dried version of smallpox vaccine

Bavarian Nordic A/S (OMX: BAVA) announced today that the US authorities have initiated negotiations for a new contract to develop a freeze-dried version of the IMVAMUNE(R) smallpox vaccine.

25 Aug 2009

Alpharx completes lyophilization process for Zysolin

AlphaRx Inc. has announced that it has completed the lyophilization process for Zysolin(TM), allowing the company to proceed to clinical batch material manufacturing for human trials. This process has been solely developed by AlphaRx's scientists and the resulting formulations have been successfully tested in animal studies conducted by the U.S. Army under a Material Transfer Agreement.

17 Aug 2009

Berries show to have a genome-wide effect on the expression of genes involved in cancer development

New research strongly suggests that a mix of preventative agents, such as those found in concentrated black raspberries, may more effectively inhibit cancer development than single agents aimed at shutting down a particular gene.

27 Aug 2008

GlaxoSmithKline acquires vaccine R&D and manufacturing plant in the U.S.

GlaxoSmithKline has announced that it is expanding its ability to increase vaccines supplies for Americans by acquiring a vaccine research and production facility in Marietta, Pennsylvania.

1 Sep 2005

Embryonic stem cells attached to a gel matrix instead of suspended in solution

30 Mar 2004

New storage method amplifies cells available for science

Like many other kinds of cells used in biomedical research, human embryonic stem cells are stored and transported in a cryopreserved state, frozen to -320 degrees Fahrenheit, the temperature of their liquid nitrogen storage bath. But when scientists thaw the cells for use in the lab, less than 1 percent awake from their frigid slumber and assume their undifferentiated state. This 'blank slate' form is characteristic of stem cells and essential for the basic science required before the promising cells are ready for the clinic.

30 Mar 2004