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Plant-derived compound helps restore cancer cells' sensitivity to treatment

A natural plant compound may help overcome a built-in defense that allows many cancers to resist a class of drugs designed to restore normal gene activity, according to a study by researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center.

2 Nov 2026

Global pediatric stroke burden remains high despite declining mortality

Pediatric stroke has been less recognized than adult stroke, and its risk factors, epidemiology and outcomes remain insufficiently understood.

2 Nov 2026

Gene therapy successfully corrects genetic defect in alpha-1 antitrypsin deficiency

In a landmark achievement in the field of genetic medicine, researchers have reported the very first published case in a peer-reviewed journal of a successful clinical treatment of a patient with alpha-1 antitrypsin deficiency (PiZZ) using in vivo gene therapy.

2 Nov 2026

Wearable devices and AI provide early warning signs of hypertensive crises

Using artificial intelligence (AI) to analyze patterns in measures from a portable cuff-based blood pressure monitor and health data from a wrist-worn device may help identify when adults with stage 2 high blood pressure (blood pressure ≥140/90 mm Hg) are at increased risk of a dangerously high blood pressure episode (>180/120 mm Hg with acute end-organ damage), known as a hypertensive crisis, up to three days before it occurs, according to new, independent, preliminary research to be presented at the American Heart Association's Scientific Sessions 2026.

2 Nov 2026

Younger adults in America's famous Blue Zone are eating differently

A cross-sectional study of 615 adults in the Loma Linda Blue Zone area and surrounding communities found that vegetarian diets were more common among older adults and Seventh-day Adventists, with vegetarians also reporting significantly lower BMI than non-vegetarians. The findings raise concerns about whether younger generations are maintaining the region's traditional dietary practices, although further research is needed to establish whether vegetarian adherence is declining over time.

2 Nov 2026

Study uncovers why pulmonary hypertension patients report symptoms of cognitive decline

University of Pittsburgh and UPMC researcher-clinicians have uncovered why many pulmonary hypertension patients report symptoms of cognitive decline.

2 Nov 2026

New hormone receptor strategy offers targeted treatment for lupus

Researchers at the University of California, Riverside and City of Hope have identified a new strategy for treating systemic lupus erythematosus (SLE), or lupus, an autoimmune disease in which the immune system attacks healthy tissues.

2 Nov 2026

Spatial study maps active epithelial crosstalk driving chronic periodontitis

Epithelial barriers are active organizers of tissue homeostasis, immune surveillance and host defense, yet chronic inflammation can corrupt their repair and communication with connective tissue.

2 Nov 2026

New pediatric consensus standardizes surgical management of Wilms tumor

WT outcomes have improved substantially through progress in molecular diagnosis, chemotherapy, radiotherapy, and surgery. Yet surgical management remains inconsistent, especially for large tumors, adjacent-organ invasion, intravascular extension, nephron-sparing surgery (NSS), and lymph node biopsy.

2 Nov 2026

New study links cannabis use to increased cardiovascular risk

Cannabis use, including marijuana, appears to be linked with increased cardiovascular risk, especially for stroke, making it an important consideration for heart disease and stroke prevention and counseling, according to independent, new preliminary research to be presented at the American Heart Association's Scientific Sessions 2026.

2 Nov 2026

Extreme heat spikes hospital intensive care cardiac arrest admissions

As daily temperatures climbed above 90 degrees Fahrenheit (F) across the U.S., so did the rate of out-of-hospital (OHCA) cardiac arrest admissions to hospitals intensive care units (ICUs); however, the heat didn't appear to impact the overall outcomes of people admitted for cardiac arrest during heat waves compared to other times, according to new, independent, preliminary research to be presented at the American Heart Association's Resuscitation Science Symposium 2026.

2 Nov 2026

New age-specific prediction models improve incomplete Kawasaki disease diagnosis

Incomplete Kawasaki disease (IKD) remains hard to recognize because it often lacks the classic signs of complete Kawasaki disease (CKD), yet delayed diagnosis can lead to coronary artery damage.

2 Nov 2026

Mount Sinai receives NIH grant to study advanced MRI methods for locating seizures

Researchers at the Icahn School of Medicine at Mount Sinai have received more than $3 million from the National Institutes of Health (NIH) for a five-year study of advanced magnetic resonance imaging (MRI) methods that may help locate seizure-causing brain regions in people with drug-resistant epilepsy.

2 Nov 2026

Study identifies new targets for antiviral drugs against coronaviruses

A study led by researchers at the University of California San Diego School of Medicine and University of California, Riverside (UCR) School of Medicine has identified new targets for antiviral drugs against coronaviruses, including SARS-CoV-2, the virus that causes COVID-19.

2 Nov 2026