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New drug delivers promising survival gains in pancreatic cancer

About 90% of people with pancreatic cancer have pancreatic ductal adenocarcinoma (PDAC), which is driven by an activating mutation in the KRAS gene.

9 Aug 2026

Study uncovers molecular trigger behind pyrin inflammation in familial Mediterranean fever

Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease in which the body's own immune system overreacts to minimal or inappropriate stimuli, producing recurrent attacks of fever and painful inflammation.

7 Aug 2026

Ion channel TPC1 identified as key regulator of iron homeostasis

Researchers have deciphered the role of an ion channel in iron homeostasis, opening up new possibilities for treating iron metabolism disorders.

6 Aug 2026

Long-acting HIV prevention tools could help close the gap before a vaccine arrives

A review of non-vaccine HIV interventions highlights the strong preventive effects of long-acting PrEP, sustained ART, U=U, vertical transmission programs, and voluntary medical male circumcision. Gene editing and multispecific antibodies may expand future options, but safety, cost, access, adherence, and implementation barriers remain.

5 Aug 2026

Obscure X chromosome protein emerges as key driver in several cancers

A little-known protein encoded on the X chromosome is attracting growing attention for its potential role in cancer development and treatment.

5 Aug 2026

Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the publication of a collaborative study in the journal npj Precision Oncology.

4 Aug 2026

Penn State study identifies genetic regions linked to avian herpesvirus virulence

A highly contagious herpes virus causes Marek's disease, a deadly illness that mainly infects chickens. While it does not make people sick, the virus causes tumors and paralysis in chickens and, if unchecked, can spread rapidly through entire flocks.

3 Aug 2026

Advances in X chromosome inactivation open therapeutic opportunities for X-linked genetic disorders

A new review explores how advances in understanding X chromosome inactivation (XCI) are creating potential therapeutic opportunities for a range of X-linked genetic disorders, including Rett syndrome, Fabry disease, Duchenne muscular dystrophy, hemophilia, and others.

3 Aug 2026

AI-powered blood test detects liver cancer across distinct populations

Researchers at the Johns Hopkins Kimmel Cancer Center validated an artificial intelligence (AI)-powered blood test that accurately detected liver cancer in people from two geographically and biologically distinct populations and also uncovered the underlying biological signals that make the test effective.

31 Jul 2026

New mechanism linked to septic heart injury protection uncovered

Sepsis triggers widespread inflammation, circulatory failure and metabolic stress, and cardiac dysfunction is a common complication associated with sharply poorer outcomes.

31 Jul 2026

Genetic variants interact to increase early-onset atrial fibrillation risk

An estimated 10 million Americans have atrial fibrillation (AFib), according to the National Institutes of Health's National Heart, Lung, and Blood Institute.

31 Jul 2026

Accumulation of somatic mutations drives vascular damage in people with progeria

Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature aging.

31 Jul 2026

Scientists uncover how muscle actin filaments grow and renew themselves

Biophysicists unraveled a mystery of how muscles form at the molecular level and how they maintain their function.

29 Jul 2026

Deramiocel cell therapy slows muscle and heart damage in advanced DMD

A cell therapy called deramiocel could slow muscle weakening in boys and young men with advanced Duchenne muscular dystrophy (DMD), and may also slow heart damage in those who already have heart muscle disease, a phase 3 clinical trial published in The Lancet has found.

29 Jul 2026

Overactive brain immune response linked to rare, severe genetic epilepsy

An overactive immune response in the brain may play a role in Dravet Syndrome, a rare and severe genetic epilepsy that typically begins in infancy, according to Weill Cornell Medicine researchers.

29 Jul 2026

Small changes in one heart protein cause distinct cardiomyopathies

Cardiomyopathies are a group of mostly hereditary, rare heart diseases in which the structure of the heart muscle tissue is impaired.

29 Jul 2026

New gene editing tool reduces Huntington's symptoms in mice

A gene editing tool designed to precisely rewrite the gene that causes Huntington's disease reduced toxic protein fragments and symptoms associated with the disease in mice, researchers at the University of Illinois Urbana-Champaign report.

29 Jul 2026

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.

28 Jul 2026

Rare BTK mutation drives resistance to targeted therapies for blood cancer

Scientists at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, and collaborators have uncovered a rare genetic mutation that enables some blood cancers to evade both approved Bruton tyrosine kinase (BTK) inhibitors and newer BTK degraders, a finding that could help shape the next generation of therapies for patients with chronic lymphocytic leukemia (CLL) and related malignancies.

27 Jul 2026

Study links inherited genetics to cancer susceptibility and progression

Scientists have found the first direct evidence of the powerful role our genetic makeup plays in influencing our risk of cancer, with inherited genes interacting with acquired genetic mutations to shape how tumors evolve.

26 Jul 2026