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Protein targeted by cancer drugs may help the body fight influenza

A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX).

18 Mar 2026

Can eating almonds reduce inflammation in obesity?

Adding almonds to the diet of adults with obesity enhances inflammatory cytokine profiles and diet quality, highlighting a simple anti-inflammatory strategy.

12 Mar 2026

AI-powered wearable ECG system detects myocardial ischemia minutes earlier

Myocardial ischemia, the primary driver of heart attacks, remains the leading cause of death and disability worldwide. Delays in diagnosis directly correlate with increased myocardial necrosis, higher complication rates, and elevated mortality.

10 Mar 2026

Researchers discover protein that promotes natural dental pulp tissue regeneration

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth vitality.

10 Mar 2026

Targeting Wnt signaling to solve the dental pulp challenge

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a transcriptional complex with β-catenin in human dental pulp stem cells, activating Wnt signaling and promoting regenerative gene expression.

9 Mar 2026

How somatic mutations shape disease and reveal new drug targets

Researchers reviewed how somatic mutations accumulate in normal and diseased tissues, showing that natural selection can expand clones that influence disease risk, tissue adaptation, or cellular resilience. The study proposes somatic genomics as a powerful strategy to uncover disease mechanisms and identify new therapeutic targets across multiple conditions.

8 Mar 2026

Nearly 70 weeks after infection, long COVID patients show no detectable inflammation in blood tests

A controlled Norwegian case-control study examined circulating biomarkers of inflammation and neuronal injury in people with long COVID about 69 weeks after infection. The researchers found no significant differences in systemic inflammatory or neuroinjury markers compared with recovered controls after statistical correction.

4 Mar 2026

How zinc deficiency could worsen heart inflammation and what that means for patients

This review examines how zinc regulates inflammatory and redox signaling pathways involved in myocarditis and pericarditis, highlighting mechanisms such as NF-κB inhibition and the redox zinc switch. The authors conclude that maintaining optimal zinc status may support cardiovascular resilience, while emphasizing that clinical translation requires further targeted trials.

1 Mar 2026

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four weeks, and potentially even at the start of treatment, according to new research published in The Journal of Nuclear Medicine.

27 Feb 2026

Study finds brain changes related to worse memory in football players with repetitive head impacts

In former college and professional football players, a new study has found higher levels of inflammation were associated with worse brain structure, which in turn was related to worse memory.

25 Feb 2026

Discovery offers hope for reducing immune-related heart risks in cancer patients

For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives.

20 Feb 2026

Gut microbiome may shape response to GLP-1 drugs, new review suggests

This review examines how GLP-1 receptor agonists and the gut microbiome influence one another through bile acid signaling, short-chain fatty acids, and inflammatory pathways. It explores how microbial composition may shape treatment response and highlights the need for controlled human studies to enable microbiome-informed precision therapy.

19 Feb 2026

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, inflammatory, mitochondrial, and proteostasis pathways. Evidence from mechanistic, preclinical, and early clinical studies suggests potential neuroprotective effects, but definitive disease-modifying benefit remains unproven.

17 Feb 2026

Study links microbe-rich diets with better insulin and cholesterol markers

This exploratory Australian study developed a database to estimate live microbe content in foods and examined associations with cardiometabolic health indicators in adults. Higher intake of foods estimated to contain live microbes was linked with favourable markers such as higher HDL cholesterol and lower BMI, insulin, and waist circumference, although causality cannot be inferred.

16 Feb 2026

Do cocoa flavanols influence heart and fatty liver risk factors?

A recent Nutrients review examined whether cocoa-rich dark chocolate influences cardiovascular and metabolic dysfunction-associated steatotic liver disease risk factors through antioxidant, anti-inflammatory, and endothelial effects. Evidence suggests modest improvements in biomarkers, but most data come from short-term studies, so definitive clinical benefits remain unproven.

16 Feb 2026

Chronic inflammation shapes cancer progression and immunotherapy response

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

16 Feb 2026

Role of food nutrients in reducing oxidative stress linked to micro- and nanoplastics

This narrative review examines how micro- and nanoplastics may contribute to oxidative stress, inflammation, and metabolic dysfunction, including potential links with diabetes. It highlights plant-derived nutrients that activate the Nrf2 pathway as a possible strategy to enhance cellular stress resilience, although most evidence remains preclinical.

15 Feb 2026

Osteoprotegerin links bone metabolism to cardiovascular disease

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Osteoprotegerin (OPG), a glycoprotein in the tumor necrosis factor superfamily, regulates bone metabolism by suppressing the formation and activation of osteoclasts.

13 Feb 2026

Diacerein shows promise as disease-modifying therapy in rheumatoid arthritis

Announcing a new publication for Acta Materia Medica journal. Diacerein, an anthraquinone derivative, is emerging as a promising disease-modifying agent in rheumatoid arthritis (RA), because of its potent anti-inflammatory and chondroprotective actions.

13 Feb 2026

DNA barcoding can be used to track cancer cells in solid and liquid biopsies

Australian scientists have discovered that DNA barcoding can be used to track cancer cells in solid and liquid biopsies, empowering future research into more reliable breast cancer diagnosis and treatment strategies.

11 Feb 2026

Necrosis News and Research

Protein targeted by cancer drugs may help the body fight influenza

Can eating almonds reduce inflammation in obesity?

AI-powered wearable ECG system detects myocardial ischemia minutes earlier

Researchers discover protein that promotes natural dental pulp tissue regeneration

Targeting Wnt signaling to solve the dental pulp challenge

How somatic mutations shape disease and reveal new drug targets

Nearly 70 weeks after infection, long COVID patients show no detectable inflammation in blood tests

How zinc deficiency could worsen heart inflammation and what that means for patients

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

Study finds brain changes related to worse memory in football players with repetitive head impacts

Discovery offers hope for reducing immune-related heart risks in cancer patients

Gut microbiome may shape response to GLP-1 drugs, new review suggests

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

Study links microbe-rich diets with better insulin and cholesterol markers

Do cocoa flavanols influence heart and fatty liver risk factors?

Chronic inflammation shapes cancer progression and immunotherapy response

Role of food nutrients in reducing oxidative stress linked to micro- and nanoplastics

Osteoprotegerin links bone metabolism to cardiovascular disease

Diacerein shows promise as disease-modifying therapy in rheumatoid arthritis

DNA barcoding can be used to track cancer cells in solid and liquid biopsies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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