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Study reveals early nicotinamide use reduces risk of aggressive skin cancers

A large U.S. Department of Veterans Affairs cohort study found that Nicotinamide use was associated with a 14% lower risk of new keratinocyte skin cancers, driven by a 22% reduction in cSCC and no reduction in BCC. The strongest benefit (56% lower risk) appeared when nicotinamide was started after a patient’s first skin cancer, with diminishing returns after multiple cancers.

18 Sep 2025

Muscle hormone FGF21 linked to longer survival in ALS

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled "The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity."

18 Sep 2025

Contact sports tied to hidden brain damage independent of CTE

This fall, tens of millions of people will be at risk for chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated head impacts from contact sports like football, soccer, and ice hockey, or military service.

17 Sep 2025

Repetitive head impacts trigger early brain changes in young athletes

Research supported by the National Institutes of Health (NIH) shows that repeated head impacts from contact sports can cause early and lasting changes in the brains of young- to middle-aged athletes.

17 Sep 2025

How to feasibly combine brief psychotherapy with medication visits

Abbreviated, 15- to 30-minute medication visits have become common in psychiatry now that many insurers model their reimbursement patterns on internal medicine and surgery.

16 Sep 2025

Caregiver personas offer insights for improving dementia medication management

Understanding the strategies and unmet needs of caregivers managing medications for people with Alzheimer's disease or related dementias may improve the lives of both caregivers and patients.

13 Sep 2025

New tool helps identify risky medications for older cancer patients

New research published in the September 2025 issue of JNCCN-Journal of the National Comprehensive Cancer Network validates the use of a specifically-curated tool for determining which medications may be causing harm for older patients with cancer.

10 Sep 2025

New clinical trial to test sensory-enabled neural prostheses for upper limb amputees

Technology developed at Case Western Reserve University can restore a sense of touch that makes a prosthetic hand feel like a part of one's own body instead of feeling artificial and disconnected.

5 Sep 2025

Smoking fuels pancreatic cancer growth through immune suppression

A new study explains why smokers have a higher chance of developing pancreatic cancer and why they tend to have worse outcomes than nonsmokers.

4 Sep 2025

UCLA Health receives NIH grant to expand innovative chronic pain therapy for veterans

UCLA Health has received a $7.1 million grant from the National Institutes of Health to expand research into a newer form of psychotherapy that has been shown to more significantly alleviate chronic pain among older adults compared to traditional cognitive behavioral therapy.

3 Sep 2025

Gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

1 Sep 2025

New mouse models reveal mechanisms of RP59 retinal degeneration

Retinitis pigmentosa retinal degeneration is caused by a family of hereditary mutations in nearly 100 genes that slowly lead to blindness over years or decades.

29 Aug 2025

Insurance status influences survival chances for critically ill patients

Does insurance play a role in which critically ill patients live or die? The unfortunate answer may be yes, due in part to a difference in the rate of inter-hospital transfer, according to new research from the University of Michigan.

26 Aug 2025

Hypothalamic neurons help maintain blood sugar during daily activities

The brain controls the release of glucose in a wide range of stressful circumstances, including fasting and low blood sugar levels.

21 Aug 2025

Scientists decode inner speech from brain activity with high accuracy

Scientists have pinpointed brain activity related to inner speech-the silent monologue in people's heads-and successfully decoded it on command with up to 74% accuracy.

14 Aug 2025

New research explores foot positioning to treat knee osteoarthritis

Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an uncurable disease in which the cartilage cushion inside a joint breaks down.

13 Aug 2025

Personalized gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

12 Aug 2025

Congress looks to ease restrictions on veterans’ use of non-VA clinics and hospitals

John-Paul Sager appreciates the care he has received at Department of Veterans Affairs hospitals and clinics, but he thinks it should be easier for veterans like him to use their benefits elsewhere.

6 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

New treatment shows greater success in reducing binge eating among veterans

Researchers from University of California San Diego have found that a novel treatment called regulation of cues combined with behavioral weight loss (ROC+BWL) was more effective than standard cognitive behavioral therapy (CBT) in reducing binge eating among veterans with overweight or obesity.

4 Aug 2025