Xenotransplantation News and Research

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Researchers identify potential therapeutic targets for treatment of neuroblastoma

A team of researchers, led by Patrick Mehlen, at Universit- de Lyon, France, has identified the protein NT-3 and the cell-surface molecule to which it binds (TrkC) as potential therapeutic targets for the treatment of neuroblastoma - the most frequent solid tumor in young children- by studying human neuroblastoma cells in vitro and after xenotransplantation into mice and chicks.

15 Feb 2010

Clinical trial raises hope for Australian diabetics to be insulin free

A clinical trial for a new treatment for type 1 diabetes which potentially eliminates the need for daily insulin injections will commence in New Zealand by Australian company Living Cell Technologies (LCT).

23 Jun 2009

Cell transplantation and diabetes: New sites, new devices

Early attempts at islet cell transplantation to treat diabetes date to the nineteenth century, decades before the discovery of insulin in the 1930s.

21 Jan 2009

New Zealand to trial pig cells as treatment for type 1 diabetes

Authorities in New Zealand have given conditional approval for a human trial to go ahead using pig cells to treat type 1 diabetes.

21 Oct 2008

Treating diabetics with pig islet cells

As the fourth-leading cause of death in developed countries, diabetes can truly be called a modern-day plague.

9 Jan 2008

Research identifies how insulin-producing islet cells from pigs may cure diabetes

Within three years, insulin-producing islet cells from pigs may be used in clinical trials on a path to finally cure insulin dependant diabetes.

13 Sep 2007

Xenotransplantation from pigs getting closer

Experiments using pigs genetically engineered for compatibility with the human immune system have raised hopes that cross-species transplantation could soon become an option for patients with diabetes and other currently incurable diseases.

20 Jul 2007

Call for change in regulations surrounding xenotransplantation

A new article in The Journal of Law, Medicine and Ethics calls for a change in the regulations surrounding xenotransplantation, the transplanting of animal cells, tissues or organs into humans.

29 Jun 2007

Xenotransplantation - what are the barriers?

Given the huge shortage of donor organs, researchers have been trying to find ways to transplant animal organs across different species (known as "xenotransplantation"), with the eventual aim of transplanting animal organs into humans.

2 Apr 2007

Major step forward for islet transplantation in diabetes patient

Living Cell Technologies Limited has announced it has published evidence outlining the survival and identification of live porcine islet cells and insulin production in a human patient 10 years after receiving a pig islet cell transplant.

2 Apr 2007

Pig cell implants show potential for treatment of stroke, Huntington's disease

A review of accumulated evidence on the use of porcine brain choroid plexus (CP) cells published in the July issue of Xenotransplantation highlights that these cells have the potential to treat acute and chronic brain disease.

24 Jul 2006

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

A team of researchers from the University of Alberta, the Yerkes National Primate Research Center of Emory University and the Emory Transplant Center has successfully transplanted insulin-producing neonatal porcine islet cells into monkeys, a procedure the researchers say represents a promising intermediate solution to the critical supply problem in clinical islet cell transplantation.

27 Feb 2006

Pig islets successfully reversed diabetes in monkeys

Researchers at the University of Minnesota's Diabetes Institute for Immunology and Transplantation have successfully reversed diabetes in monkeys using transplanted islet cells from pigs.

19 Feb 2006

Transplantation of organs from animals to humans could soon be a reality

Speaking at the BA Festival of Science in Dublin, Dr Anthony Warrens, discussed how xenotransplantation, the process of transplanting organs from one species into another, could soon be a reality, easing the current shortage of organs for transplantation.

10 Sep 2005

The ethics of face transplants

The ethics of face transplants is among the issues to be discussed at the World Congress of Bioethics, which will be hosted by the University of New South Wales (UNSW) next week.

4 Nov 2004

Non-human primates should never be considered as source animals for any future clinical trials of animal-to-human transplantation

Australia’s leading health advisory body, the National Health and Medical Research Council, says there should be a five-year moratorium on any clinical research into animal-to-human whole organ transplants in Australia.

20 Sep 2004

We want to figure out how to grow new kidneys in humans

Growing new organs to take the place of damaged or diseased ones is moving from science fiction to reality, according to researchers at Washington University School of Medicine in St. Louis.

22 Jun 2004