Zoloft News and Research

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Zoloft is a drug used to treat depression. It is a type of selective serotonin reuptake inhibitor (SSRI). Also called sertraline.

As depression symptoms improve with antidepressants, hopelessness can linger

People taking medication for depression typically see a lot of improvements in their symptoms during the first few months, but lagging behind other areas is a sense of hopefulness, according to new research from the University of Michigan Health System.

18 Feb 2008

Selective publication means unfavorable drug studies rarely get published

A new report claims that almost a third of the research done on antidepressant drugs is never published in medical literature and most of those unpublished reports are unfavorable.

20 Jan 2008

SSRIs may double risk of gastrointestinal bleeding

New research shows that selective serotonin reuptake inhibitors (SSRIs), a group of drugs commonly used to treat depression, may double the risk of gastrointestinal bleeding, according to researchers from Wake Forest University School of Medicine and colleagues.

9 Oct 2007

Top five prescribed drugs

With a total nearly $5 billion, Lipitor, a cholesterol-reducing drug, ranked first in terms of total spending on prescription medicines by adults ages 18 to 64 in 2004, and another cholesterol-fighting drug, Zocor, ranked fourth at $2.3 billion, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

21 Sep 2007

Exercise as effective for depression as drugs

A study of adults suffering from depression has found that regular exercise is just as effective as medication for improving symptoms.

20 Sep 2007

Antidepressants during pregnancy present remote risk of birth defects

According to the latest research the newer antidepressant drugs known as selective serotonin reuptake inhibitors (SSRIs) only slightly increase the risk of birth defects in pregnancy.

28 Jun 2007

FDA - all antidepressants need new warning labels

The Food and Drug Administration (FDA) in the United States wants the manufacturers of antidepressant medications to change the labels on their products.

3 May 2007

Benefits of antidepressants for children far outweigh the risks

Researchers in the United States maintain that a review of research shows that the benefits of antidepressants for children and teens during the first few months of treatment far outweigh the risk of suicide.

22 Apr 2007

TV ads for drugs high on the emotions but low on facts

According to a new study television commercials for prescription drugs are heavily loaded on the emotional side but offer scant information on the disease itself and do little to promote the benefits of a healthy lifestyle.

30 Jan 2007

FDA announces tentative approval of generic Zoloft

Lupin Pharmaceuticals, Inc. announced that the U.S. Food and Drug Administration (FDA) has granted tentative approval for the Company's Abbreviated New Drug Application (ANDA) for Sertraline Hydrochloride Tablets, 25mg, 50mg and 100mg.

2 Jan 2007

Potential for first diagnostic DNA test to guide antidepressant treatment

Treatment of depression is difficult for both patients and for psychiatrists. While there are numerous drugs available that work, finding the right one -- or right combination -- is, at times, a matter of trial and error.

31 Oct 2006

Prozac saves thousands of lives

A new study should help alleviate any concern over a link between the use of certain antidepressants and suicide.

13 Jun 2006

Zoloft may prevent recurrence of depression in patients with diabetes

A team of researchers at Washington University School of Medicine in St. Louis found that an antidepressant medication may reduce the risk of recurrent depression and increase the length of time between depressive episodes in patients with diabetes.

9 May 2006

Antidepressant suicide risk up five times for seniors

According to Canadian researchers seniors who are prescribed antidepressants such as Prozac, Paxil and Zoloft are almost five times more likely to commit suicide during the first month on the drugs than those given other medication to treat depression.

3 May 2006

Popular antidepressants may affect fetus

A team from the Ottawa Health Research Institute, the University of Ottawa, and The Ottawa Hospital has found an increased risk of premature delivery, low birth weight, fetal death, and infant seizures among pregnant women who used a popular class of antidepressants during pregnancy.

20 Apr 2006

Depression treatment may require different drugs for different people

If a first antidepressant medication doesn't work, try a different one, UT Southwestern Medical Center researchers report.

27 Mar 2006

Antidepressants may affect fetus

A University of California, San Diego (UCSD) School of Medicine collaborative study with Boston University's Slone Epidemiology Center found an increased risk of persistent pulmonary hypertension (PPHN) in newborns of mothers who used certain commonly prescribed antidepressants in late pregnancy.

20 Feb 2006

SSRI antidepressants may also affect human immune system

Drugs that treat depression by manipulating the neurotransmitter serotonin in the brain may also affect the user's immune system in ways that are not yet understood, say scientists from Georgetown University Medical Center and a Canadian research institute.

23 Jan 2006

Transport mechanisms for serotonin

Researchers at The Forsyth Institute have discovered that the transport mechanisms for serotonin - the chemical substance involved in transmitting signals between neurons, and which has a role in anxiety and mood disorders - play a key role in determining where organs are positioned in the body during embryonic development.

7 Dec 2005

Adverts for SSRI antidepressants misleading

Consumer ads for a class of antidepressants called SSRIs often claim that depression is due to a chemical imbalance in the brain, and that SSRIs correct this imbalance, but these claims are not supported by scientific evidence, say researchers in PLoS Medicine.

13 Nov 2005