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Older Americans living alone often rely on neighbors or others willing to help

Donald Hammen, 80, and his longtime next-door neighbor in south Minneapolis, Julie McMahon, have an understanding. Every morning, she checks to see whether he's raised the blinds in his dining room window. If not, she'll call Hammen or let herself into his house to see what's going on.

12 Nov 2024

Major funding deficit deepens Syria’s mental health crisis

Reeling from the effects of civil war and natural disaster, northern Syria is in the grip of a mental health crisis, as suicide rates soar and funding for services falls short.

4 Nov 2024

Researchers develop the first polymer-based therapeutic for Huntington’s disease

Breakthrough polymer-based therapy shows promise in reversing Huntington's disease symptoms by preventing toxic protein clumps and enhancing neuronal survival.

4 Nov 2024

Novel method boosts MSC efficacy for articular cartilage repair

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, alongside collaborators from the National University of Singapore Tissue Engineering Programme (NUSTEP), have developed a novel method to enhance the ability of mesenchymal stromal cells (MSCs) to generate cartilage tissue by adding ascorbic acid (AA) during MSC expansion.

18 Oct 2024

Targeting tumor immunity with transferrin receptor-directed photodynamic therapy

This new article publication from Acta Pharmaceutica Sinica B, discusses a transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB interruption.

26 Sep 2024

These Alabama workers were swamped by medical debt. Then their employer stepped in.

Like most medical offices, the small suite of exam rooms at the PhiferCares Clinic fills daily with patients seeking help with bumps and bruises, sore throats, and stuffy noses.

19 Sep 2024

Tossed medicine, delayed housing: How homeless sweeps are thwarting Medicaid’s goals

Andrew Douglass shoved his clothes and belongings into plastic trash bags as five police officers surrounded his encampment — a drab gray tent overflowing along a bustling sidewalk in the gritty Tenderloin neighborhood, where homeless people lie sprawled on public sidewalks, sometimes in drug overdoses.

16 Sep 2024

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Study identifies phenylacetylglutamine (PAGln), a gut microbiome metabolite, as a novel allosteric modulator of β2-adrenergic receptors, offering insights into its role in cardiovascular disease (CVD) risk.

26 Aug 2024

USC researchers develop new sleep analysis tool based on heart data

We know that quality sleep is as essential to survival as food and water. Yet, despite spending a third of our lives in slumber, it largely remains a scientific mystery.

19 Aug 2024

AlphaFold accelerates discovery of potential antipsychotic drugs by outperforming traditional methods

Researchers used AlphaFold and homology modeling to identify potent TAAR1 agonists, showing AlphaFold's superior performance in drug discovery for neuropsychiatric conditions.

13 Aug 2024

Cell nuclei found to control tissue architecture in eye and brain development

In work conducted both at UC Santa Barbara and the Physics of Life Excellence Cluster of TU Dresden, biophysicist Otger Campàs and his research group have found that cell nuclei control the architecture and mechanics of eye and brain tissues during embryonic development.

12 Aug 2024

LGBTIQ+ and cisgender heterosexual individuals exhibit more stress hormones during controversial campaign

How did the 2021 national marriage equality referendum campaign in Switzerland affect the well-being of the LGBTIQ+ community?

24 Jul 2024

Study: Women with severe endometriosis 10 times more likely to get ovarian cancer

A landmark study from researchers at Huntsman Cancer Institute at the University of Utah (the U), the Spencer Fox Eccles School of Medicine at the U, and Boston University Chobanian & Avedisian School of Medicine found that women with severe endometriosis are 10 times more likely to get ovarian cancer, compared to women who do not have the disease.

18 Jul 2024

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Tirzepatide, a novel twincretin drug, significantly improves weight loss and glycemic control in obese and type 2 diabetes patients, outperforming traditional treatments in clinical trials.

15 Jul 2024

FDA approved PDE4 inhibitor roflumilast for atopic dermatitis

On July 9th, 2024, the U.S. FDA approved Arcutis Biotherapeutics' ZORYVE® (roflumilast) for treating atopic dermatitis (AD), the most common type of eczema affecting millions in the U.S. This once-daily, steroid-free cream could become a new standard of care for AD.

From Sino Biological Inc. 12 Jul 2024

Liver's defense mechanism hinders immunity in chronic hepatitis B, study reveals

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. A team from the Technical University of Munich (TUM) has discovered that cells blood vessels in the liver start a "sleep timer" that switches off immune cells. Targeting this mechanism could be a starting point for immunotherapies.

11 Jul 2024

New deadly strain of mpox found in DRC could spread exponentially among humans

Concerns are growing about an outbreak of deadly mpox caused by a novel, sexually transmitted strain of the virus in the southeast of the Democratic Republic of Congo (DRC).

5 Jul 2024

Supreme Court OKs local crackdowns on homelessness, as advocates warn of chaos

The U.S. Supreme Court's watershed decision on homelessness Friday will make it easier for elected officials and law enforcement authorities nationwide to fine and arrest people who live on streets and sidewalks, in broken-down vehicles, or within city parks — which could have far-reaching health consequences for homeless Americans and their communities.

28 Jun 2024

Innovative Pop-Up Safety Town initiative promotes child safety across Michigan

Jamie Hector smiled as his 6-year-old daughter Coral chose a red bike helmet at the Pop-Up Safety Town event at a local school gymnasium.

20 Jun 2024

Study reveals cognitive benefits of ketogenic diet in aged mice

The impact of cyclic ketogenic diet treatments in improving the age-related decline in brain function.