Bacterial News and Research

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Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

QRICH1 protein discovery opens new avenues for cancer and autoimmune therapies

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

AI model enhances detection of antibiotic resistance in deadly bacteria

Drug-resistant infections - especially from deadly bacteria like tuberculosis and staph - are a growing global health crisis.

7 Apr 2025

New guidelines aim to improve diagnosis and treatment of mycoplasma pneumoniae in children

The Chinese Medical Association has released new guidelines for diagnosing and treating Mycoplasma pneumoniae in children.

7 Apr 2025

New antibody research sparks hope for better whooping cough vaccines

Whooping cough, or pertussis, was once a leading cause of death for children in the U.S. and worldwide before the introduction of vaccines in the 1940s.

7 Apr 2025

Scientists engineer promising vaccine target for Lyme disease

Meeting the unmet need for a vaccine is the top priority for researchers studying Lyme disease, which infects about 476,000 people in the U.S. each year and can come with severe complications such as ongoing fatigue and joint issues.

7 Apr 2025

Treating SIBO holistically helps patients feel better, new study finds

A 90-day real-world study in Spain shows that a comprehensive, personalized treatment for SIBO significantly improves patients’ quality of life—even when breath tests remain abnormal.

7 Apr 2025

New study reveals hidden spread of C. diff in intensive care units

One of the most common health care-associated infections spreads within intensive care units (ICUs) more than three times more than previously thought, new research has found.

4 Apr 2025

New insights into bacterial defense mechanisms could help combat antibiotic resistance

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades.

4 Apr 2025

Innovative oral vaccine strategy combats intestinal pathogens

The issue of intestinal bacteria is a complex one. On the one hand, we are dependent on the microorganisms because they are the ones that digest the food in our intestine.

4 Apr 2025

European study reveals stabilization patterns in antibiotic resistance

Antibiotic resistance tends to stabilize over time, according to a study published April 3, 2025 in the open-access journal PLOS Pathogens by Sonja Lehtinen from the University of Lausanne, Switzerland, and colleagues.

4 Apr 2025

Study: Jumbo phages utilize EPI vesicles to evade bacterial immune response

In a growing global trend, bacteria have evolved new ways to maneuver around medical treatments for a variety of infections. The rising antibiotic resistance crisis poses a significant public health threat in hospitals and other settings, with infections resulting in millions of deaths in recent years.

4 Apr 2025

Enhanced tuberculosis detection in advanced HIV using stool molecular testing

The Xpert MTB/Ultra molecular diagnostic test for stool samples, until now recommended only for children, could be established as an additional test for diagnosing tuberculosis in adults living with HIV.

4 Apr 2025

New bacterial evolutionary map could lead to precision treatments for infections

The first-of-its-kind in-depth bacterial evolutionary map could pave the way for the development of precision treatments for certain antibiotic-resistant infections, such as urinary tract infections.

3 Apr 2025

Sweetener saccharin revives old antibiotics by breaking bacterial defences

Saccharin destabilizes bacterial membranes and interferes with DNA replication, causing lysis and impairing virulence traits. The sweetener also re-sensitizes multidrug-resistant pathogens to antibiotics and disrupts stubborn biofilms.

3 Apr 2025

Gut bacteria may reduce the effectiveness of common medications

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

3 Apr 2025