Cell Death News and Research

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Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.

21 Jun 2023

New embryonic cell type that self-destructs to protect the developing fetus discovered

Scientists studying gene activity data of the early human embryo have discovered an overlooked type of cell which self-destructs within days of forming, as part of a quality control process to protect the developing fetus.

20 Jun 2023

CBD and THC: promising remedies for aluminum-related neurological damage

Researchers assessed the protective effect of CBD and THC oils against aluminum toxicity.

20 Jun 2023

Research explores complex relationship between cholesterol and breast cancer risk

Research explores the complex relationship between cholesterol and breast cancer risk, with some studies suggesting an increased risk with elevated cholesterol levels while others find an inverse association.

15 Jun 2023

Using ultrasound for an effective sonodynamic treatment of orthotopic pancreatic cancer

Ultrasound is a promising technique for treating cancer. Unlike laser light, used in photodynamic cancer therapy, ultrasound waves can reach deep into tissue - up to 12 cm - to treat deep tumors without damaging healthy cells.

14 Jun 2023

Bergamot fiber shows promise in battling neurodegenerative disorders

Bergamot fiber (BF), a byproduct of citrus fruit processing, shows antioxidant properties and protects against neurotoxicity induced by amyloid beta protein (Aβ), suggesting potential benefits for Alzheimer's disease treatment and waste reduction.

13 Jun 2023

Scientists uncover the structure of the first step in amyloid formation for Huntington's disease

Devastating neurodegenerative diseases like Huntington's, Alzheimer's, and Parkinson's are all associated with protein deposits in the brain, known as amyloid.

13 Jun 2023

Researchers identify microRNAs associated with a weakened immune response to COVID-19

A team of researchers at NYU Abu Dhabi, led by Associate Professor of Biology Youssef Idaghdour and working in collaboration with clinicians at several Abu Dhabi hospitals, investigated the association between microRNAs, a class of small RNA molecules that regulate genes, and COVID-19 severity among 259 unvaccinated COVID-19 patients living in Abu Dhabi.

11 Jun 2023

SARS-CoV-2 virus can cause brain cells to fuse: Study

Researchers at The University of Queensland have discovered viruses such as SARS-CoV-2 can cause brain cells to fuse, initiating malfunctions that lead to chronic neurological symptoms.

8 Jun 2023

Study identifies a promising target for development of vaccine against spotted fever

A protein found in cells of the hard tick Amblyomma sculptum, the main vector of the bacterium that causes Brazilian spotted fever (also known as Rocky Mountain spotted fever), is essential to the tick's survival while feeding, making it a promising target for development of a vaccine, according to an article published in the journal Parasites & Vectors.

7 Jun 2023

New insights into the mechanisms underlying progression of Huntington's disease

New research led by a University of Ottawa Faculty of Medicine team is providing compelling insights into the mechanisms underlying the progression of Huntington's disease in an animal model.

7 Jun 2023

Innovative probe could deepen the understanding of key cellular messenger and lead to new drug discoveries

A ground-breaking study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic drugs.

5 Jun 2023

Research opens door to new, more efficient drug combinations for acute myeloid leukemia

Acute myeloid leukemia (AML) is a very aggressive disease in which cells proliferate abnormally, invading the bone marrow and interfering with normal blood cell production. It is the most common acute leukemia in adults with the worst prognosis.

5 Jun 2023

Study shows efficacy and safety of novel FolRα-targeting antibody drug conjugate in recurrent epithelial ovarian cancer

Updated dose expansion data of the phase I STRO-002-GM1 study have been presented today by Ana Oaknin, Principal Investigator of the Vall d'Hebron Institute of Oncology's (VHIO) Gynecological Malignancies Group, on the ground at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO), 2-6 June in Chicago, USA.

4 Jun 2023

Cell Death News and Research

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

New embryonic cell type that self-destructs to protect the developing fetus discovered

CBD and THC: promising remedies for aluminum-related neurological damage

Research explores complex relationship between cholesterol and breast cancer risk

Using ultrasound for an effective sonodynamic treatment of orthotopic pancreatic cancer

Bergamot fiber shows promise in battling neurodegenerative disorders

Scientists uncover the structure of the first step in amyloid formation for Huntington's disease

Researchers identify microRNAs associated with a weakened immune response to COVID-19

SARS-CoV-2 virus can cause brain cells to fuse: Study

Study identifies a promising target for development of vaccine against spotted fever

New insights into the mechanisms underlying progression of Huntington's disease

Innovative probe could deepen the understanding of key cellular messenger and lead to new drug discoveries

Research opens door to new, more efficient drug combinations for acute myeloid leukemia

Study shows efficacy and safety of novel FolRα-targeting antibody drug conjugate in recurrent epithelial ovarian cancer

Researchers characterize a unique molecular mechanism of early stages of programmed cell death

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

First-in-human clinical trial of liver dialysis device successfully completed

Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

Energy drinks may stunt muscle repair, new study suggests

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