Microarray News and Research

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New glycan arrays discover autoimmunogenic activities of SARS-CoV

Researchers in New York City and Guangzhou, China applied the rapidly-developing carbohydrate microarray technology to study an inactivated SARS-coronavirus (SARS-CoV) vaccine and discovered autoimmunogenic activity of this newly identified human viral pathogen.

2 Aug 2004

Surprising differences in the DNA of normal cells from different people

A new study by Michael Wigler’s group at Cold Spring Harbor Laboratory has, in collaboration with researchers from Karolinska Institutet, revealed surprising differences in the DNA of normal cells from different people.

23 Jul 2004

New DNA microarray to speed bone disease research

Velcura Therapeutics has announced the development of a custom Affymetrix GeneChip(R) array that aids the development of bone disease therapies by enabling researchers to follow global changes in gene expression during human bone formation.

23 Jul 2004

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

At the XVth International AIDS Conference in Bangkok, Thailand, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases and chief of the NIAID Laboratory of Immunoregulation (LIR), will present his laboratory’s latest findings on how aberrant immune activation underlies HIV pathogenesis.

15 Jul 2004

Recent tuberculosis research holds promise for developing a more effective vaccine

Tuberculosis, a mycobacterium that infects human lungs, still claims the lives of about 2 million people every year. Existing vaccines provide questionable protection, and they can even cause disease in individuals with compromised immune systems.

9 Jul 2004

Chromatin array a new technology for examining DNA

A new technique for examining DNA is giving scientists a more detailed picture of which genes have the propensity for activation, offering a new tool for understanding how genes function and possibly for diagnosing disease.

8 Jul 2004

New gene selection method

Current microarray experiments allow the levels of activity of thousands of genes to be measured at once, providing a window into molecular events underlying health and disease.

8 Jul 2004

Gene chip technology can detect one of the commonest cystic fibrosis (CF) genetic mutations with 100% accuracy

A single genetic test that is capable of detecting all mutations involved in the development of cystic fibrosis could be just a few years away, the 20th annual conference of the European Society of Human Reproduction and Embryology heard today (Monday 28 June).

28 Jun 2004

Microchip to track genetic signature of cancer and normal tissue

MicroRNAs (miRNAs), tiny pieces of genetic material that can serve as stop signs for gene expression and protein synthesis, are thought to be important in the development of cancer.

23 Jun 2004

Discovery of a gene-expression signature common to distinct types of cancer

Researchers at the University of Michigan, Johns Hopkins and the Institute of Bioinformatics in India have discovered a gene-expression "signature" common to distinct types of cancer

23 Jun 2004

Australian frog could boost the prospects of maintaining human muscle strength into old age

Scientific studies of a unique Australian frog could lead to the development of new ways to improve livestock production levels and boost the prospects of maintaining human muscle strength into old age.

21 Jun 2004

New embryonic stem cells technology

An MIT team has developed new technology that could jump-start scientists' ability to create specific cell types from human embryonic stem cells, a feat with implications for developing replacement organs and a variety of other tissue engineering applications.

14 Jun 2004

Biologist has identified gene patterns that characterize a biologically distinct subtype of estrogen receptor negative breast tumor

University of North Carolina molecular biologist Charles Perou has identified the pattern of genes that characterize a biologically distinct subtype of estrogen receptor negative breast tumor.

14 Jun 2004

Synthetic skin from human embryonic stem cells

A Massachusetts Institute of Technology team has developed new technology that could jump-start scientists' ability to create specific cell types from human embryonic stem cells, a feat with implications for developing replacement organs and a variety of other tissue engineering applications.

14 Jun 2004

Better understanding of Tamoxifen and how breast cancer patients develop resistance

A new study by researchers at Georgetown’s Lombardi Comprehensive Cancer Center may have implications for the thousands of breast cancer patients who develop resistance to antiestrogen drugs such as Tamoxifen®. The work is published in the June 1 issue of Cancer Research.

11 Jun 2004

New statistical techniques for cancer diagnosis

CSIRO statisticians have developed a new way to subtype paediatric Acute Lymphoblastic Leukaemia (ALL), the most common form of cancer in children under 12.

9 Jun 2004

Fibroid tumors lack crucial structural protein

Fibroid tumors-the sometimes painful uterine growths affecting many American women-lack a key protein that plays a role in holding tissues together, according to a study by researchers from the Uniformed Services University of the Health Sciences (USUHS) and the National Institute of Child Health and Human Development of the National Institutes of Health

3 Jun 2004

Fibroid tumors affecting many American women lack a key protein helps hold tissues together

Fibroid tumors — the sometimes painful uterine growths affecting many American women — lack a key protein that plays a role in holding tissues together, according to a study by researchers from the Uniformed Services University of the Health Sciences (USUHS) and the National Institute of Child Health and Human Development of the National Institutes of Health.

2 Jun 2004

Discovery of a key marker in breast cancer tumors

Cancer researchers at Georgetown University Medical Center have discovered a key marker in breast cancer tumors that may help determine which women with early stage breast cancer have a better chance of survival. The research appears in the June 1 issue of the Journal of Clinical Oncology.

31 May 2004

Standardizing procedures to ensure the reliability and comparability of results from microarrays

Microarrays, sometimes called "gene chip" devices, enable researchers to monitor the activities of thousands of genes from a single tissue sample simultaneously, identifying patterns that may be novel indicators of disease status.

24 May 2004