Omicron News and Research

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Study looks at boosting with variant-derived COVID vaccine

In a recent study posted to bioRxiv*, researchers at Washington University School of Medicine, St. Louis, demonstrated that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine booster elicits robust germinal center (GC) B cell responses.

26 Sep 2022

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Researchers explored RRIs [long-range ribonucleic acid (RNA)-RNA interactions] in SARS-CoV-2 variants of concern genomes to assess evolutionary changes in SARS-CoV-2.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

In a new study, researchers investigated the receptor tropism and serological cross-reactivity for spike (S) protein receptor-binding domains from two clade 3 sarbecoviruses found in Russian Rhinolophus (horseshoe) bats.

26 Sep 2022

Is covid ‘under control’ in the US? Experts say yes

President Joe Biden caused a stir in a “60 Minutes” interview on Sept. 18 when he declared that the covid-19 pandemic is over.

26 Sep 2022

How effective are live-attenuated SARS-CoV-2 vaccines?

Researchers opined on the use of live-attenuated whole virus vaccines as COVID-19 vaccines.

26 Sep 2022

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

The findings of a new Swedish study posted to the Preprints with The Lancet* server found that two COVID-19 vaccine doses provided effective long-term protection against infection before Omicron, but less protection against Omicron infection (dropping to 43% by week four and no protection by week 14).

25 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

Study shows 72% increase in new diagnoses of type 1 diabetes in young COVID-19 patients

Children who were infected with COVID-19 show a substantially higher risk of developing type 1 diabetes (T1D), according to a new study that analyzed electronic health records of more than 1 million patients ages 18 and younger.

23 Sep 2022

Study describes the dynamics of immune responses to triple COVID-19 vaccination

The effectiveness of the three-dose COVID-19 vaccination against SARS-CoV-2 and its variants has been described in detail in a recent study.

23 Sep 2022

Vaccine boosters and breakthrough infections provide substantial immunity against COVID-19

Vaccine boosters and breakthrough infections following vaccination both provide a substantial and potentially pandemic-breaking immunity against COVID-19, according to new laboratory research from Oregon Health & Science University.

22 Sep 2022

Sarbecovirus discovered in Russian bat can infect humans and is resistant to SARS-CoV-2 vaccines

A recently discovered virus in a Russian bat that is similar to SARS-CoV-2, the virus behind COVID-19, is likely capable of infecting humans and, if it were to spillover, is resistant to current vaccines.

22 Sep 2022

Study reveals the long-term neurologic consequences of COVID-19

If you've had COVID-19, it may still be messing with your brain. Those who have been infected with the virus are at increased risk of developing a range of neurological conditions in the first year after the infection, new research shows.

22 Sep 2022

Does BA.2 breakthrough infection shift cross-neutralization activity towards the BA.4 and BA.5 Omicron sublineages?

Researchers investigated the SARS-CoV-2 VOC Omicron's immune escape mechanisms.

22 Sep 2022

Deep mutational scanning for SARS-CoV-2 Omicron BA.1 and BA.2 subvariants

Researchers performed deep mutational scanning for the SARS-CoV-2 Omicron variant of concern sub-VOC BA.1 and BA.2 receptor-binding domains.

22 Sep 2022

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

In a recent study published in the journal PNAS, researchers from Finland and the United States reported a novel heptad repeat 2 (HR2) peptide that inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) without any chemical modifications.

21 Sep 2022

Omicron News and Research

Study looks at boosting with variant-derived COVID vaccine

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

Is covid ‘under control’ in the US? Experts say yes

How effective are live-attenuated SARS-CoV-2 vaccines?

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

Study shows 72% increase in new diagnoses of type 1 diabetes in young COVID-19 patients

Study describes the dynamics of immune responses to triple COVID-19 vaccination

Vaccine boosters and breakthrough infections provide substantial immunity against COVID-19

Sarbecovirus discovered in Russian bat can infect humans and is resistant to SARS-CoV-2 vaccines

Study reveals the long-term neurologic consequences of COVID-19

Does BA.2 breakthrough infection shift cross-neutralization activity towards the BA.4 and BA.5 Omicron sublineages?

Deep mutational scanning for SARS-CoV-2 Omicron BA.1 and BA.2 subvariants

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

Covid still kills, but the demographics of its victims are shifting

Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

Study reveals improved immunogenicity and safety of bivalent Omicron-containing mRNA-1273.214 candidate booster vaccine

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