Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Childhood epilepsy linked to late-onset brain amyloid disorders

Researchers from the University of Turku and Åbo Akademi University in Finland and the University of Wisconsin in the United States demonstrated that individuals who had childhood epilepsy have an increased accumulation of brain amyloid later in life, potentially predisposing them to late-onset brain amyloid disorders, such as Alzheimer's disease.

22 Jan 2025

Researchers uncover how PICH protein protects DNA during cell division

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

21 Jan 2025

New imaging protocol enhances visualization of rare bone marrow cells

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to accurately identify rare LepR+ stromal cells.

21 Jan 2025

Antihistamines offer new hope for erythropoietic protoporphyria-related liver disease

Chlorcyclizine shows promise in reducing protoporphyrin-IX accumulation and liver damage in erythropoietic protoporphyria, targeting histamine pathways.

20 Jan 2025

New rabbit model provides insights into CF-related pancreatic endocrine pathology

Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication.

17 Jan 2025

DDR2 enhances BMP-dependent bone regeneration and reduces heterotopic ossification

Bone loss resulting from trauma, fractures, or disease presents a major global health challenge, often leading to long-term disability.

17 Jan 2025

Granzyme K+ CD8+ T-cells identified as key drivers of recurrent airway inflammation

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

17 Jan 2025

Scientists discover new mechanism behind Huntington’s disease brain cell death

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

16 Jan 2025

A new AI tool for unlocking the secrets of spatial multi-omics in cancer

A new artificial intelligence-powered tool called MISO (Multi-modal Spatial Omics) can detect cell-level characteristics of cancer by looking at data from extremely small pieces of tissue-some as small as 400 square micrometers, equivalent to the width of five human hairs.

16 Jan 2025

Tiny vesicles offer powerful new approach for cancer treatment

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Jan 2025

Xenon gas offers potential neuroprotective effects for Alzheimer's patients

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and Washington University School of Medicine in St. Louis points to a novel-and noble-approach: using Xenon gas.

16 Jan 2025

Exercise offers hope in the Alzheimer's battle

Regular aerobic exercise could significantly reduce disease markers associated with Alzheimer's, new research led by scientists at the University of Bristol (UK) and the Federal University of São Paulo (Brazil) has found. The findings provide new hope in the battle against this devastating disorder.

16 Jan 2025

Panakeia launches AI-driven PANProfiler Colon for rapid cancer profiling

Panakeia (“the Company”), a pioneer in AI-driven multi-omic biomarker profiling, today announces the launch of PANProfiler Colon, an AI-driven software solution for profiling of Microsatellite instability (MSI) and mismatch repair deficiency (dMMR) entirely digitally and directly from Hematoxylin and Eosin (H&E)-stained images of colon cancer tissue samples.

15 Jan 2025

Spear Bio secures FDA breakthrough device designation for its novel pTau 217 blood test, advancing scalable solutions for early Alzheimer's disease diagnosis

Spear Bio Inc., a biotechnology company pioneering next-generation ultra-sensitive immunoassays, today announced that its pTau 217 blood test has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA).

From Spear Bio 15 Jan 2025

Researchers uncover new mutation mechanism driving cancer progression

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery or amputation.

15 Jan 2025

Blood vessel dysfunction in brain's temporal lobes linked to mild cognitive impairment

Mild cognitive impairment is linked to blood vessel dysfunction in the brain's temporal lobes - the seat of memory - according to a new USC-led study.

13 Jan 2025

Mayo Clinic Digital Pathology aims to revolutionize pathology and accelerate medical breakthroughs

Against the backdrop of the 43rd Annual J.P. Morgan Healthcare Conference, Mayo Clinic announced the formation of Mayo Clinic Digital Pathology, designed on a platform architecture to boldly unlock the power of its extensive archive of digital slides to revolutionize pathology and accelerate medical breakthroughs.

13 Jan 2025