G Protein News and Research

RSS

Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

Alnylam Pharmaceuticals a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-TTRsc, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR).

19 Mar 2013

Research provides better understanding of microbiological factors of periodontitis

Microbes from the human mouth are telling Oak Ridge National Laboratory scientists something about periodontitis and more after they cracked the genetic code of bacteria linked to the condition.

19 Mar 2013

ProtiDiet High Protein Chocolate Dream Bars may contain Salmonella, warns FDA

Pro-Amino International Inc. is recalling protein bars which may contain Salmonella. The product is the ProtiDiet High Protein Chocolate Dream Bar, sold in 210 gram (7.4 oz.) packages, 7 bars per package, bearing UPC 6 21498 42238 1, lot code CR 18 13B, and Best Before date of 2015-08.

19 Mar 2013

Study investigates prognostic indicators for BCa patients treated with RC

A new study from Japan investigated various prognostic indicators, including clinico-pathological and pre-operative hematological factors to develop a novel prognostic factors-based risk stratification model for disease-specific survival in bladder cancer patients treated with radical cystectomy.

19 Mar 2013

Controlling hypertension earlier in life may limit brain changes associated with Alzheimer's disease

A study in the JAMA Neurology (formerly the Archives of Neurology) suggests that controlling or preventing risk factors such as hypertension earlier in life may limit or delay the brain changes associated with Alzheimer's disease and other age-related neurological deterioration.

19 Mar 2013

Pregnancy-associated plasma protein A predicts cardiovascular events: Study

Higher levels of pregnancy-associated plasma protein A were associated with an increased risk of cardiovascular events in people with cardiac chest pain that developed as a result of heart disease/coronary artery disease, according to a study published in CMAJ.

19 Mar 2013

Migraine severity may be predicted by blood levels of fat cell hormone

In a small, preliminary study of regular migraine sufferers, scientists have found that measuring a fat-derived protein called adiponectin (ADP) before and after migraine treatment can accurately reveal which headache victims felt pain relief.

18 Mar 2013

Study reveals potential markers for treating patients with metastatic clear cell RCC

Markers such as CA9, CD31, CD34 and VEGFR1/2 in the primary tumours might serve as predictors of a good response to a sunitinib treatment in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to a new study to be presented at the 28th Annual EAU Congress currently on-going in Milan.

18 Mar 2013

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Mycolactone activation of N-WASP boosts Buruli ulcer formation

Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers.

18 Mar 2013

Cytomegalovirus employs a novel trick to hide from immune detection

A virus that most people have probably never heard of, yet most of us carry, is the number 1 infectious cause of congenital birth defects. One in 750 children are born with, or develop, permanent disabilities such as hearing loss or brain damage as a result of CMV (cytomegalovirus) infection in the womb.

17 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Researchers identifiy elusive anti-cancer property of vitamin E

Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find. Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits.

16 Mar 2013

Discovery could lead to new target for treatment of cocaine addiction

Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.

16 Mar 2013

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs).

15 Mar 2013

Luminex collaborates with Merck to design companion diagnostic device for Alzheimer’s disease

WHITEHOUSE STATION known as MSD outside the United States and Canada, and Luminex Corporation have signed a collaboration and license agreement to develop a companion diagnostic device that will be evaluated to help screen patients for recruitment into Merck's clinical development program for MK-8931, a novel oral beta amyloid precursor protein site cleaving enzyme (BACE) inhibitor and Merck's lead investigational candidate for Alzheimer's disease (AD).

From Luminex 15 Mar 2013

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific for proteins on the outside of the virus, specifically the hemagglutinin protein.

15 Mar 2013

Brown fat cells protective against obesity and diabetes

Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating warmth might also be applied to coping with obesity and diabetes.

15 Mar 2013

Fast-progressing hearing impairment linked to fatal Creutzfeldt-Jakob Disease

Rapid hearing loss in both ears may be a symptom of the rare but always-fatal Creutzfeldt-Jakob Disease and should be considered a reason for clinicians to test for the disorder.

15 Mar 2013

Researchers identify enzymes that activate coronavirus for infection

Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate the virus for infection.

15 Mar 2013

G Protein News and Research

Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

Research provides better understanding of microbiological factors of periodontitis

ProtiDiet High Protein Chocolate Dream Bars may contain Salmonella, warns FDA

Study investigates prognostic indicators for BCa patients treated with RC

Controlling hypertension earlier in life may limit brain changes associated with Alzheimer's disease

Pregnancy-associated plasma protein A predicts cardiovascular events: Study

Migraine severity may be predicted by blood levels of fat cell hormone

Study reveals potential markers for treating patients with metastatic clear cell RCC

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Mycolactone activation of N-WASP boosts Buruli ulcer formation

Cytomegalovirus employs a novel trick to hide from immune detection

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Researchers identifiy elusive anti-cancer property of vitamin E

Discovery could lead to new target for treatment of cocaine addiction

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

Luminex collaborates with Merck to design companion diagnostic device for Alzheimer’s disease

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Brown fat cells protective against obesity and diabetes

Fast-progressing hearing impairment linked to fatal Creutzfeldt-Jakob Disease

Researchers identify enzymes that activate coronavirus for infection

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News