immunity News and Research

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Appendix and tonsil surgeries before age 20 can increase risk of premature heart attack

The surgical removal of the appendix and tonsils before the age of 20 was associated with an increased risk of premature heart attack in a large population study performed in Sweden. Tonsillectomy increased the risk by 44% (hazard ratio 1.44) and appendectomy by 33% (HR 1.33).

1 Jun 2011

Natural killer cells promote induction of dry eye disease: New discovery

If you are one of the millions of people around the world who struggle with dry eye disease, good news is on the way. A new research discovery published in the Journal of Leukocyte Biology offers hope for new drugs that treat the cellular cause of the disease rather than its symptoms.

1 Jun 2011

Scientists study key malaria protein structure to demonstrate how cells grow and move

Researchers from the Walter and Eliza Hall Institute have overturned conventional wisdom on how cell movement across all species is controlled, solving the structure of a protein that cuts power to the cell 'motor'. The protein could be a potential drug target for future malaria and anti-cancer treatments.

31 May 2011

Scientists discover new mechanism that controls inflammation

The molecular machines that defend our body against infection don't huff and puff, but some of them apparently operate on the same principle as a steam engine.

26 May 2011

New study shows that closing schools, other measures limited H1N1 spread in Mexico

The H1N1 virus was new, and most of the cases occurred among young people. Health professionals and scientists weren’t sure at the onset what the world would encounter with the virus.

24 May 2011

Fluorinated glucosamine blocks synthesis of key sugar linked to skin inflammation, cancer progression

Charles J. Dimitroff, MS, PhD and colleagues in the Dimitroff Lab at Brigham and Women's Hospital, have developed a fluorinated analog of glucosamine, which, in a recent study, has been shown to block the synthesis of key carbohydrate structures linked to skin inflammation and cancer progression. These findings appear in the April 14, 2011, issue of the Journal of Biological Chemistry.

24 May 2011

Novel hepatitis C-like virus discovered in dogs

In a study to be published online this week in the Proceedings of the National Academy of Sciences, researchers report the discovery of a novel hepatitis C-like virus in dogs. The identification and characterization of this virus gives scientists new insights into how hepatitis C in humans may have evolved and provides scientists renewed hope to develop a model system to study how it causes disease.

24 May 2011

Tumor necrosis factor can suppress inflammation, treat rheumatoid arthritis

A new study by rheumatologists at Hospital for Special Surgery in New York has shown that a powerful pro-inflammatory protein, tumor necrosis factor, can also suppress aspects of inflammation.

23 May 2011

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Mosquitoes are becoming more resistant to current pesticides. That's troubling to Kansas State University biologist Kristin Michel, as it means malaria and other mosquito-borne diseases will continue spreading. A recent grant from the National Institutes of Health may change all that.

18 May 2011

Antiretrovirals important to protect HIV-positive children from measles

Scientific American looks at the possible link between HIV prevalence and a recent increase in the number of children dying from measles in sub-Saharan Africa. "Studies show that infants with HIV do not respond well to the measles vaccine even when given a second dose at nine months, as the World Health Organization currently recommends," the article notes.

17 May 2011

Lower education leads to faster ageing: Study

According scientists, people who leave education with fewer qualifications are prone to age more quickly. The research was published in the journal Brain, Behavior and Immunity on Wednesday.

15 May 2011

Gene manipulation can improve survival rates during sepsis infection

Sepsis is a major killer in hospital intensive care units. Researchers at Case Western Reserve University School of Medicine have found that manipulating a genetic factor that can launch or throttle the body's defenses can improve survival rates during bacterial infection.

13 May 2011

Salmonella enterica bacterium activates virulence genes through Fur protein

Salmonella enterica, one of the main causes of gastrointestinal infections, modulates its virulence gene expression, adapting it to each stage of the infection process, depending on the free iron concentration found in the intestinal epithelium of its host.

12 May 2011

Patients with pneumonia more likely to die if they have Vitamin D deficiency

A new study published in the journal Respirology reveals that adult patients admitted to the hospital with pneumonia are more likely to die if they have Vitamin D deficiency.

11 May 2011

New book explores the hidden world of viruses

"Carl Zimmer is one of the best science writers we have today. A Planet of Viruses is an important primer on the viruses living within and around all of us-sometimes funny, other times shocking, and always accessible. Whether discussing the common cold and flu, little-known viruses that attack bacteria or protect oceans, or the world's viral future as seen through our encounters with HIV or SARS, Zimmer's writing is lively, knowledgeable, and graced with poetic touches."-Rebecca Skloot, author of The Immortal Life of Henrietta Lacks.

7 May 2011

Latest research on HIV immunity can help develop vaccine

Latest insights into immunity to HIV could help to develop a vaccine to build antibodies' defences against the disease, a University of Melbourne, Australia study has found.

7 May 2011

Researchers find temperature-sensing protein in immune cells

Researchers at The Scripps Research Institute have found a temperature-sensing protein within immune cells that, when tripped, allows calcium to pour in and activate an immune response.

7 May 2011

Study offers means of activating T cells to fight disease without antigenic triggers

For much of the time our T cells-the white blood cells that act as the police of the immune system-are in what immunologists call a "quiescent state," a sort of standby mode. For years, scientists have wondered if quiescence occurred by default or whether T cells need to work at remaining silent.

6 May 2011

H. pylori DNA may help treat severe colitis

DNA from Helicobacter pylori, a common stomach bacteria, minimizes the effects of colitis in mice, according to a new study by University of Michigan Medical School scientists.

6 May 2011

UCF to develop safe, inexpensive and effective polio vaccine

An innovative way of making vaccines at the University of Central Florida has attracted the support of the Bill & Melinda Gates Foundation for its potential to make vaccines lessexpensive, more effective and needle free.

5 May 2011