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Research finding may offer future alternative to antibiotics

A team of scientists from government, academia and private industry has developed a novel treatment that protects mice from infection with the bacterium that causes tularemia, a highly infectious disease of rodents, sometimes transmitted to people, and also known as rabbit fever. In additional experiments with human immune cells, the treatment also demonstrated protection against three other types of disease-causing bacteria that, like the tularemia bacteria, occur naturally, can be highly virulent, and are considered possible agents of bioterrorism.

28 May 2010

Use of lubricants with anal sex associated with increased risk of rectal sexually transmitted infections

The risk of acquiring HIV through unprotected anal sex is at least 20 times greater than with unprotected vaginal sex and increases if other infections are already present in the rectal lining. Could the use of lubricants - at least certain kinds - be another risk factor among men and women who engage in receptive anal intercourse? Two studies presented today at the International Microbicides Conference in Pittsburgh, suggest the answer is yes.

27 May 2010

National Science Foundation supports PolyMedix with $150,000 grant for development of antimicrobial sutures

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat serious acute cardiovascular disorders and infectious diseases, has received a grant in the amount of $150,000 from the National Science Foundation to support the development of antimicrobial sutures. PolyMedix has developed a series of novel antimicrobial polymers for device and material applications, which it collectively calls the PolyCides™.

27 May 2010

Bacteria may play wider role in people predisposed to obesity: Researchers

Bacteria may play more of a role in people predisposed to obesity than previously thought, according to studies presented today by University of Maryland School of Medicine researchers at the 110th general meeting of the American Society for Microbiology in San Diego.

27 May 2010

ifp Institut für Produktqualität sells molecular biological, PCR-based food test product line to QIAGEN

The Berlin-based diagnostics company ifp Institut für Produktqualität has sold its molecular biological, PCR-based food test product line to QIAGEN at a price not revealed. QIAGEN has purchased all the required patents and licences and will immediately begin to market and distribute the newly acquired portfolio of 70 molecular biological tests. With the support of this powerful and experienced partner in food diagnostics ifp can now make available its expertise in food analytics globally.

From QIAGEN Manchester Limited 26 May 2010

QIAGEN acquires rights to 70 molecular food safety tests developed by Institute for Product Quality

QIAGEN today announced that it has entered into an agreement with the Institute for Product Quality (ifp), pursuant to which QIAGEN has acquired all rights to 70 molecular food safety tests developed by the Berlin-based specialized laboratory center for food analysis.

From QIAGEN Manchester Limited 26 May 2010

Researchers examine association between use of antibiotics and outcomes among patients with COPD

Among patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease, those who received antibiotics in the first 2 hospital days had improved outcomes, such as a lower likelihood of mechanical ventilation and fewer readmissions, compared to patients who received antibiotics later or not at all, according to a study in the May 26 issue of JAMA.

26 May 2010

Natural anti-inflammatory protein effective against meningitis-causing bacteria

A study published online on May 24th in the Journal of Experimental Medicine (www.jem.org) suggests that boosting the abundance of one of the body's own proteins might be more effective than antibiotic treatment at fighting off a common meningitis-causing bacterium (E. coli K1).

25 May 2010

Silver nanoparticles effective at killing all kinds of bacteria

Writing in the International Journal of Nanoparticles, Rani Pattabi and colleagues at Mangalore University, explain how blasting silver nitrate solution with an electron beam can generate nanoparticles that are more effective at killing all kinds of bacteria, including gram-negative species that are not harmed by conventional antibacterial agents.

25 May 2010

Sorrento Therapeutics receives STTR grant to develop antibody therapeutics to combat MRSA

Sorrento Therapeutics, Inc. today announced that it has received an Advanced Technology Small Business Technology Transfer Research grant from the National Institute of Allergy and Infectious Diseases. The peer-reviewed grant was awarded to support the Company's program to generate and develop novel antibody therapeutics and vaccines to combat Staphylococcus aureus infections, including methicillin-resistant S. aureus, by disrupting quorum sensing, a bacterial communication process essential to virulence.

21 May 2010

New synthesized genome may lead to advances in health and biotechnology

The successful construction of a synthesized genome could enable new research and development of human therapies, biofuels, and biobased chemicals from renewable resources.

21 May 2010

JCVI researchers construct first self-replicating, synthetic bacterial cell

Researchers at the J. Craig Venter Institute (JCVI), a not-for-profit genomic research organization, published results today describing the successful construction of the first self-replicating, synthetic bacterial cell. The team synthesized the 1.08 million base pair chromosome of a modified Mycoplasma mycoides genome.

21 May 2010

Ectoin shows positive effect on nanoparticle-induced lung inflammation: Study

bitop AG, which specializes in the development and marketing of Ectoin-containing medical devices, announces that Ectoin significantly reduces nanoparticle-induced inflammatory reaction in rat lungs, one of the animal models for chronic obstructive pulmonary disease. It is the first time that Ectoin has been shown to have such an effect on nanoparticle-induced lung inflammation.

20 May 2010

Trius awarded new DTRA contract for developing novel antibiotics against gram-negative bacterial pathogens

Trius Therapeutics, Inc. today announced that it has been awarded a new four and a half year contract from the Defense Threat Reduction Agency (DTRA), an agency within the U.S. Department of Defense, for the development of novel antibiotics directed against gram-negative bacterial pathogens. Trius may receive up to $29.5 million in support of development efforts under the new DTRA contract, which is funded as part of DTRA's Transformational Medical Technologies Initiative (TMTI).

20 May 2010

Kansas State University researcher awarded NIH grant to study antibiotic-resistant bacteria

Antibiotic-resistant bacteria are becoming a growing problem around the world, and are a particular worry in hospital-acquired infections.

20 May 2010

FDA approves ZYMAXID ophthalmic solution for treatment of bacterial conjunctivitis

Allergan, Inc. today announced that the United States Food and Drug Administration has approved ZYMAXID (gatifloxacin ophthalmic solution) 0.5%, a topical fluoroquinolone anti-infective indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms; Haemophilus influenzae, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumonia.

20 May 2010

Experimental evolution used to develop new strains of bacteria for use as probiotic substances

When the forces of evolution took over an experimental strain of bacteria, it derailed an experiment Duke and NC State researchers thought they were conducting, but led to something much more profound instead.

19 May 2010

Vaccinations recommended for adults

Yearly vaccinations aren't just for kids any more. You probably heard a lot about a seasonal or H1N1 flu shot last fall, but you should know that a battery of other adult vaccinations might also become part of your health care routine. Pneumonia and shingles vaccines are preventive-care essentials for older adults, and meningitis and tetanus shots are now college rites of passage. Even the vaccines of childhood—measles, mumps and rubella, and whooping cough—are recommended for adults who missed out in their younger years.

19 May 2010

Antibiotics have significant resistance effects on individual patients in primary care

Antibiotics prescribed in primary care make a considerable contribution to the problem of antimicrobial resistance, both in individual patients and the population as a whole, according to research from the University of Bristol published in this week’s BMJ.

18 May 2010

Human stem cells restore alveolar epithelial tissue after E. coli endotoxin-induced ALI: Researchers

Human stem cells administered intravenously can restore alveolar epithelial tissue to a normal function in a novel ex vivo perfused human lung after E. coli endotoxin-induced acute lung injury, according to research from the University of California San Francisco.

18 May 2010

Bacterial News and Research

Research finding may offer future alternative to antibiotics

Use of lubricants with anal sex associated with increased risk of rectal sexually transmitted infections

National Science Foundation supports PolyMedix with $150,000 grant for development of antimicrobial sutures

Bacteria may play wider role in people predisposed to obesity: Researchers

ifp Institut für Produktqualität sells molecular biological, PCR-based food test product line to QIAGEN

QIAGEN acquires rights to 70 molecular food safety tests developed by Institute for Product Quality

Researchers examine association between use of antibiotics and outcomes among patients with COPD

Natural anti-inflammatory protein effective against meningitis-causing bacteria

Silver nanoparticles effective at killing all kinds of bacteria

Sorrento Therapeutics receives STTR grant to develop antibody therapeutics to combat MRSA

New synthesized genome may lead to advances in health and biotechnology

JCVI researchers construct first self-replicating, synthetic bacterial cell

Ectoin shows positive effect on nanoparticle-induced lung inflammation: Study

Trius awarded new DTRA contract for developing novel antibiotics against gram-negative bacterial pathogens

Kansas State University researcher awarded NIH grant to study antibiotic-resistant bacteria

FDA approves ZYMAXID ophthalmic solution for treatment of bacterial conjunctivitis

Experimental evolution used to develop new strains of bacteria for use as probiotic substances

Vaccinations recommended for adults

Antibiotics have significant resistance effects on individual patients in primary care

Human stem cells restore alveolar epithelial tissue after E. coli endotoxin-induced ALI: Researchers

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