Immune System News and Research

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Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Crigler-Najjar syndrome affects about one in a million people at birth. Because of a defective gene, these individuals lack an essential enzyme in their liver to eliminate bilirubin, a toxic bile pigment that accumulates in all body tissues causing jaundice and potentially leading to irreversible and lethal neurological damage.

28 Feb 2019

Structure of human type 2 cannabinoid receptor revealed

A Chinese research team joined forces with Russian and U.S. biologists to obtain the crystal structure of the human type 2 cannabinoid receptor.

28 Feb 2019

Researchers explore why common antibiotic prescribed for diarrhea is failing

In the world of superbugs (bacteria that has grown resistant to antibiotics) Clostridioides difficile, a bacterium that causes diarrhea and colitis, is among the most stubborn.

27 Feb 2019

Custom-designed proteins may help generate antibodies to inhibit HIV infection

A new way to create proteins that can sneak through HIV's protective coating may be a step toward understanding the key components needed for developing a vaccine for the virus, according to researchers.

27 Feb 2019

Machine learning tool could prevent unnecessary treatments for kids with arthritis

Arthritis is not just an ailment of old age--it can affect children too, causing lifelong pain and disability in its most severe forms. Fortunately, some kids grow out of it. Knowing which patients will develop milder forms of disease could spare them unnecessary treatment and potential medication side effects but currently doctors have no way of predicting disease course or severity.

27 Feb 2019

Study uncovers mechanism that controls immune reactions against gut microbiota

Researchers from the Cluster of Excellence "Precision Medicine in Chronic Inflammation" in Kiel and Charité - Universitätsmedizin Berlin have uncovered a critical mechanism that controls immune reactions against microorganisms in the intestine.

27 Feb 2019

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019

Newly developed probe looks, acts, and feels so much like real neuron

Like a well-guarded fortress, the human brain attacks intruders on sight. Foreign objects, including neural probes used to study and treat the brain, do not last long.

26 Feb 2019

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences, and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases.

26 Feb 2019

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Scientists at the University of British Columbia have discovered a new protein "switch" that could stop the progression of blood-poisoning, or sepsis, and increase the chances of surviving the life-threatening disease.

26 Feb 2019

Pitt engineer wins $500,000 NSF CAREER award to study impact of harmful man-made chemicals

Per- and polyfluorinated alkyl substances are man-made chemicals that are useful in a variety of industries because of their durability, but do not naturally break down in the environment or human body.

26 Feb 2019

Immunologists uncover the immune system's unknown messenger

A novel messenger which alarms nearby cells when the immune system recognizes infections has been uncovered by immunologists from Aarhus University, Denmark. This knowledge will help fighting infections and autoimmune diseases.

26 Feb 2019

Cocktail of chemicals in the mother inhibits child growth

For the first time, researchers have shown that a combination of perfluorinated substances in the mother significantly inhibits child growth.

25 Feb 2019

Disease X: an unknown disease that could claim millions of lives

Dubbed ‘Disease X’, scientists believe a future epidemic of the influenza virus could cause millions of deaths worldwide.

25 Feb 2019

Risk of tick bite potentially leading to red meat allergy is higher than expected

Until now it has been believed that in order for a tick to trigger an allergic immune response to alpha-gal in humans, the tick would need to have recently fed on the alpha-gal-rich blood of a mammal.

25 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

Neighborhood income, education associated with risk of disability progression in MS patients

Neighborhood income and education level is associated with risk of disability progression in patients with multiple sclerosis, suggests new research from the University of British Columbia.

23 Feb 2019

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

The composition of the microbiome - the countless bacteria, fungi and viruses that colonize our body surface, skin, intestines or lungs - makes a decisive contribution to human health or disease.

23 Feb 2019

Akna protein plays a key role in the regulation of neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine.

22 Feb 2019

Reduced antibody adaptability may make the elderly more vulnerable to influenza

The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against new viral strains, researchers report February 19 in the journal Cell Host & Microbe.

21 Feb 2019

Immune System News and Research

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Structure of human type 2 cannabinoid receptor revealed

Researchers explore why common antibiotic prescribed for diarrhea is failing

Custom-designed proteins may help generate antibodies to inhibit HIV infection

Machine learning tool could prevent unnecessary treatments for kids with arthritis

Study uncovers mechanism that controls immune reactions against gut microbiota

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

Newly developed probe looks, acts, and feels so much like real neuron

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Pitt engineer wins $500,000 NSF CAREER award to study impact of harmful man-made chemicals

Immunologists uncover the immune system's unknown messenger

Cocktail of chemicals in the mother inhibits child growth

Disease X: an unknown disease that could claim millions of lives

Risk of tick bite potentially leading to red meat allergy is higher than expected

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Neighborhood income, education associated with risk of disability progression in MS patients

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

Akna protein plays a key role in the regulation of neural stem cells

Reduced antibody adaptability may make the elderly more vulnerable to influenza

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