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Antifungal and antidepressant drugs can effectively inhibit COVID-19 virus

New research published in the British Journal of Pharmacology indicates that two currently available medications--an antifungal drug and an antidepressant--can effectively inhibit the virus that causes COVID-19 in laboratory cells.

7 Apr 2021

Prenatal exposure to phthalates is linked to altered cognitive outcomes in infants

Exposure to phthalates, a class of chemicals widely used in packaging and consumer products, is known to interfere with normal hormone function and development in human and animal studies.

7 Apr 2021

USGS study finds high levels of arsenic and uranium in private well water across Connecticut

A new U.S. Geological Survey study provides an updated, statewide estimate of high levels of naturally occurring arsenic and uranium in private well water across Connecticut.

7 Apr 2021

Expert calls for swift action to avoid chronic health conditions caused by COVID-19

A tsunami of chronic health conditions as a result of the SARS-CoV-2 pandemic, especially cardiometabolic disease, may produce an enormous wave of death and disability that demands immediate, comprehensive strategies.

7 Apr 2021

Rice University, Houston Methodist launch collaboration to solve clinical problems with neurorobotics

Neurosurgery's history of cutting diseases out of the brain is morphing into a future in which implanting technology into the brain may help restore function, movement, cognition and memory after patients suffer strokes, spinal cord injuries and other neurological disorders.

6 Apr 2021

FDA authorizes use of Symbiotica COVID-19 Self-Collected Antibody Test System

The U.S. Food and Drug Administration today announced it has issued an emergency use authorization for the Symbiotica COVID-19 Self-Collected Antibody Test System, the first antibody test authorized for use with home collected dried blood spot samples.

6 Apr 2021

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Scientists recently explored the transmission dynamics of currently circulating variants of SARS-CoV-2 in a southern African country. By analyzing the genomic sequences of these variants, they have identified a novel SARS-CoV-2 variant with multiple spike mutations. They have temporarily designated the variant A.VOI.V2.

6 Apr 2021

Implantable sensor based on gold nanoparticles revolutionizes medical diagnostics

The idea of implantable sensors that continuously transmit information on vital values and concentrations of substances or drugs in the body has fascinated physicians and scientists for a long time. Such sensors enable the constant monitoring of disease progression and therapeutic success.

6 Apr 2021

Study suggests T-cells don't determine survival in severe COVID-19

In the study, which appeared on the pre-print server medRxiv, the team found that when the monkeys were reinfected, the T cell-depleted animals showed anamnestic immune responses, the enhanced reaction of the body's immune system to an antigen that is related to an antigen previously encountered.

6 Apr 2021

New nanoparticle SARS-CoV-2 vaccine confers robust protection with single dose after two weeks

In a methodologically ‘state-of-the-art’ approach, US researchers have developed a protein-based nanoparticle vaccine against coronavirus disease (COVID-19), with a swift generation of antibodies and the potential to protect individuals who cannot receive other COVID-19 vaccines for medical reasons. The research is posted to the bioRxiv* preprint server.

5 Apr 2021

Researchers generate a precise map of basal ganglia connectivity

Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium.

5 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

High expression of cell death genes may increase risk of early death from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

5 Apr 2021

Temple, Case Western scientists receive $3 million NIH grant to study pathway behind heart failure

Like a bad water pump that fails to circulate coolant in a car engine, a failing heart struggles to pump blood through the body, causing symptoms of fatigue, shortness of breath, and swelling in the legs and feet.

5 Apr 2021

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

The Foundation for Innovative New Diagnostics (FIND) announced today the launch of a request for proposals (RFP) to accelerate the development, manufacturing, and market availability of accurate, affordable, quality-assured and easy-to-use SARS-CoV-2 self-tests for use in low- and middle-income countries (LMICs).

5 Apr 2021

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma.

3 Apr 2021

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

A team of researchers has identified several candidates for drugs against the coronavirus SARS-CoV-2 at DESY´s high-brilliance X-ray lightsource PETRA III.

3 Apr 2021

Scientists identify nine potential new COVID-19 treatments

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.

2 Apr 2021

Suppressing facial expressions may be useful in certain contexts, shows study

How do our facial expressions in response to seeing others in pain influence how we see and feel their pain? There are many situations where it may be helpful to suppress our emotional responses to the pain of others.

2 Apr 2021

Highly contagious SARS-CoV-2 variant was spreading for months before its discovery

A highly contagious SARS-CoV-2 variant was unknowingly spreading for months in the United States by October 2020, according to a new study from researchers with The University of Texas at Austin COVID-19 Modeling Consortium.

2 Apr 2021

Laboratory News and Research

Antifungal and antidepressant drugs can effectively inhibit COVID-19 virus

Prenatal exposure to phthalates is linked to altered cognitive outcomes in infants

USGS study finds high levels of arsenic and uranium in private well water across Connecticut

Expert calls for swift action to avoid chronic health conditions caused by COVID-19

Rice University, Houston Methodist launch collaboration to solve clinical problems with neurorobotics

FDA authorizes use of Symbiotica COVID-19 Self-Collected Antibody Test System

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Implantable sensor based on gold nanoparticles revolutionizes medical diagnostics

Study suggests T-cells don't determine survival in severe COVID-19

New nanoparticle SARS-CoV-2 vaccine confers robust protection with single dose after two weeks

Researchers generate a precise map of basal ganglia connectivity

New RNA-sequencing method can help detect numerous modified small RNAs

High expression of cell death genes may increase risk of early death from lung cancer

Temple, Case Western scientists receive $3 million NIH grant to study pathway behind heart failure

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

Scientists identify nine potential new COVID-19 treatments

Suppressing facial expressions may be useful in certain contexts, shows study

Highly contagious SARS-CoV-2 variant was spreading for months before its discovery

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