immunity News and Research

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Protective immunity against HIV can be achieved without presence of virus neutralizing antibodies in the blood

New research shows that protective immunity against HIV can be achieved without the presence of virus neutralizing antibodies in the blood. The study, published by Cell Press in the February issue of the journal Immunity, demonstrates that a vaccine which stimulates production of specific anti-HIV antibodies in the vaginal tissue was sufficient to protect monkeys from exposure to live virus.

11 Feb 2011

Vaccinating through salivary glands may provide protection against wide range of diseases

If you don't like shots or needles, you're in luck. New research published online in The FASEB Journal gives the development of new oral vaccinations a shot in the arm thanks to discoveries involving the salivary glands of mice. In addition, this research report also offers a tantalizing glimpse of vaccines that could prevent infection at mucosal surfaces, even if direct injections into the body fail to cause immunity. This technique may be effective for a wide range of diseases from influenza to cholera.

11 Feb 2011

Richard J. Fasenmyer Foundation awards $3M to Cleveland physicians for AIDS research

A three-year, $3 million gift from the Richard J. Fasenmyer Foundation will fund research by a pair of Cleveland physicians into HIV and the body's response in autoimmune diseases.

11 Feb 2011

Global Health Consortium to support development of vaccines to control dengue fever

The International Vaccine Institute today announced the launch of the Dengue Vaccine Initiative, in collaboration with the Sabin Vaccine Institute, the Johns Hopkins University, and the World Health Organization, to support development of vaccines to control dengue fever, a widespread and expanding hemorrhagic fever that is endemic in most tropical and subtropical regions of the world.

10 Feb 2011

Vical 2010 net loss increases to $30.4 million

Vical Incorporated today reported financial results for the year ended December 31, 2010. Vical had cash and investments of approximately $61 million at year-end 2010. The company received approximately $37 million of net proceeds from the sale of equity securities during 2010.

10 Feb 2011

Avian flu vaccine stockpiled in 2004 still useful

A stockpiled vaccine designed to fight a strain of avian flu that circulated in 2004 can be combined with a vaccine that matches the current strain of bird flu to protect against a potential pandemic, researchers from Saint Louis University's Center for Vaccine Development have found.

10 Feb 2011

HIV-negative babies born to HIV-positive mothers have lower antibody levels for some infections, study finds

"Babies who are exposed to HIV at birth but don't become infected with the virus have lower levels of antibodies to diseases such as whooping cough, tetanus and pneumococcus," according to a study published in the Feb. 9 issue of the Journal of the American Medical Association (JAMA), HealthDay News/U.S. News & World Report.

10 Feb 2011

Opinions: Polio vaccines; Alternatives to DDT, insecticides; Food price volatility; Global poverty; Foreign aid for vaccines

"No one denies" that the oral polio vaccine "has considerable merits. It's cheap to make. It's easy to administer; you don't need a trained nurse with a clean syringe [like the inactive vaccine needs], just a volunteer with a dropper. And it gives excellent immunity. ... But there are problems with the method," Wendy Orent, author of the book Plague: The Mysterious Past and Terrifying Future of the World's Most Dangerous Disease, writes in a Los Angeles Times opinion piece.

10 Feb 2011

Drugs against protective action of bacteria's antitoxin molecules

Bacteria often attack with toxins designed to hijack or even kill host cells. To avoid self-destruction, bacteria have ways of protecting themselves from their own toxins.

9 Feb 2011

Babies born to HIV-infected mothers have lower antibody levels against bacterial infections

Babies whose mothers have HIV, but who are not HIV-infected themselves, are born with lower levels of specific proteins in their blood called antibodies, which fight infection, compared with babies not exposed to HIV, a new study has found.

9 Feb 2011

Researchers identify immune cell population that acts as body's border patrol with the outside world

So-called barrier sites -- the skin, gut, lung - limit the inner body's exposure to allergens, pollutants, viruses, bacteria, and parasites. Understanding how the immune system works in these external surfaces has implications for understanding such inflammatory diseases as asthma, psoriasis, IBD, and food allergies, all of which occur at the body's barriers.

8 Feb 2011

Scientists awarded grant to study microbiology of Cystic Fibrosis pulmonary infection

Scientists at Queen's University Belfast have begun work into improving the lives of thousands of Cystic Fibrosis sufferers thanks to the award of a -1.74 million US-Ireland Research and Development Partnership grant.

4 Feb 2011

Queen's awarded £1.74 million grant to study microbiology of Cystic Fibrosis pulmonary infection

Scientists at Queen's University Belfast have begun work into improving the lives of thousands of Cystic Fibrosis sufferers thanks to the award of a £1.74 million US-Ireland Research and Development Partnership grant.

4 Feb 2011

Cell signaling hormone boosts immune response to clear HIV-like infection

Australian scientists have successfully cleared a HIV-like infection from mice by boosting the function of cells vital to the immune response.

4 Feb 2011

Scientists test new dry powder measles vaccine that can be inhaled

Sustained high vaccination coverage is key to preventing deaths from measles. Despite the availability of a vaccine, measles remains an important killer of children worldwide, particularly in less-developed regions where vaccination coverage is limited. A team of researchers, led by scientists at the Johns Hopkins Bloomberg School of Public Health and the University of Colorado, developed and successfully tested a dry powder, live-attenuated measles vaccine that can be inhaled.

2 Feb 2011

Scientist identifies natural signaling molecule that can prevent Hemophilia A

A scientist from The Scripps Research Institute has identified a new role for a natural signaling molecule in preventing blood clot formation. The molecule could become a target for the development of novel and cost-effective treatments for blood clotting diseases such as Hemophilia A.

1 Feb 2011

Inovio announces regulatory approval for Phase 2 trial to treat leukemia using new vaccine delivery device

Inovio Pharmaceuticals, a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today the regulatory approval of a Phase 2 clinical trial to treat leukemia utilizing Inovio's new ELGEN 1000 automated vaccine delivery device.

31 Jan 2011

ISU researchers study parasites that cause NTDs in humans

Richard Martin, DVM, PhD, a biomedical sciences professor at Iowa State University's College of Veterinary Medicine, has devoted his 35-year career to studying nematode parasites. These parasites infect approximately one-quarter of the world population, producing debilitating symptoms that devastate the lives and economies of many of the world's underdeveloped and impoverished areas.

29 Jan 2011

Study suggests newborn diagnosis can improve survival in SCID patients

Severe Combined Immunodeficiency occurs in just one out of every 50,000 to 100,000 births in the United States, yet it is the most serious primary immunodeficiency disorder. A study published today in Blood, the Journal of the American Society of Hematology, demonstrates that babies with SCID who are diagnosed at birth and receive a hematopoietic stem cell transplant, which is the transplantation of blood-forming stem cells, have significantly improved survival.

28 Jan 2011

McGill, GSK enter collaborative research agreement on cystic fibrosis

McGill University and GlaxoSmithKline plc have signed a collaboration agreement to develop a potential breakthrough approach to treat cystic fibrosis, a fatal genetic disease. The trans-Atlantic effort between researchers from McGill's Faculty of Medicine and their GSK collaborators in the UK, will focus on developing molecules that could treat the disease by correcting the dysfunction caused by the mutated gene.

28 Jan 2011

immunity News and Research

Protective immunity against HIV can be achieved without presence of virus neutralizing antibodies in the blood

Vaccinating through salivary glands may provide protection against wide range of diseases

Richard J. Fasenmyer Foundation awards $3M to Cleveland physicians for AIDS research

Global Health Consortium to support development of vaccines to control dengue fever

Vical 2010 net loss increases to $30.4 million

Avian flu vaccine stockpiled in 2004 still useful

HIV-negative babies born to HIV-positive mothers have lower antibody levels for some infections, study finds

Opinions: Polio vaccines; Alternatives to DDT, insecticides; Food price volatility; Global poverty; Foreign aid for vaccines

Drugs against protective action of bacteria's antitoxin molecules

Babies born to HIV-infected mothers have lower antibody levels against bacterial infections

Researchers identify immune cell population that acts as body's border patrol with the outside world

Scientists awarded grant to study microbiology of Cystic Fibrosis pulmonary infection

Queen's awarded £1.74 million grant to study microbiology of Cystic Fibrosis pulmonary infection

Cell signaling hormone boosts immune response to clear HIV-like infection

Scientists test new dry powder measles vaccine that can be inhaled

Scientist identifies natural signaling molecule that can prevent Hemophilia A

Inovio announces regulatory approval for Phase 2 trial to treat leukemia using new vaccine delivery device

ISU researchers study parasites that cause NTDs in humans

Study suggests newborn diagnosis can improve survival in SCID patients

McGill, GSK enter collaborative research agreement on cystic fibrosis

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