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Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

Complex assembly process involved in DNA virus replication revealed

In a twist on the question, "Which came first, the chicken or the egg?", scientists have long faced a similar question about how human adenovirus replicates: "Which comes first, assembly of the viral particle, or packaging of the viral genome?"

5 Apr 2023

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Indiana University School of Medicine researchers have identified a promising new combination of drugs to treat juvenile myelomonocytic leukemia (JMML), a rare form of blood cancer that affects children.

5 Apr 2023

Novel combination treatment for head and neck cancers leads to antitumor effects

Human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) and lung cancer can have disruptive mutations in TP53and/or CDKN2A tumor suppressor genes, which are associated with poor patient survival.

5 Apr 2023

Study explains why leukemia survivors experience negative effects on blood formation decades later

Contrary to previous belief, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia.

5 Apr 2023

Key molecular pathway for organ damage in COVID patients discovered

Even after three years since the emergence of COVID-19, much remains unknown about how it causes severe disease, including the widespread organ damage beyond just the lungs.

5 Apr 2023

SFU researchers study pathogen genes to develop new drugs against bacterial infections

Researchers at Simon Fraser University are studying the genes of superbugs to aid the development of new and effective treatments for drug-resistant bacterial infections.

5 Apr 2023

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

The scientific foundation needed to work on curing a class of cancer-causing mutations is here, in the form of a tool from St. Jude Children's Research Hospital.

5 Apr 2023

IU researchers focus on tackling binge and "high-intensity" drinking

A multi-disciplinary team of Indiana University researchers is focusing their efforts on a growing public health concern: binge and "high-intensity" drinking - extreme drinking behaviors that are increasingly prevalent among college-age adults.

5 Apr 2023

Researchers develop a method for making “mini-heart” using pluripotent stem cells

A team at the Technical University of Munich has induced stem cells to emulate the development of the human heart.

5 Apr 2023

Scientists secure funding for cutting-edge research on age-related macular degeneration

A team of scientists led by a Northumbria University academic has won funding to research an eye disease suffered by over 190 million people worldwide.

5 Apr 2023

New anticancer agent activated by ultrasound waves does not have strong side effects

Chemotherapy treatments produce strong side effects. A new agent that accumulates in the tumor tissue and is activated thereby ultrasound waves does not have this problem.

5 Apr 2023

Scientists unearth some of the biological mechanisms behind ferroptosis

A team of researchers at Tohoku University has unearthed some of the biological mechanisms of ferroptosis, a recently discovered type of regulated cell death that is triggered by iron and the accumulation of lipid peroxidation - lipids that have undergone oxidative degeneration.

5 Apr 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023

How does nutrition affect female fertility?

A new study reviews current evidence supporting the role of nutrition as a modifiable risk factor for female infertility and poor IVF outcomes.

4 Apr 2023

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

Researchers explored the interaction of white adipose tissue mitochondria with gut microbiota in obesity.

4 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

B Cell News and Research

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Complex assembly process involved in DNA virus replication revealed

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Novel combination treatment for head and neck cancers leads to antitumor effects

Study explains why leukemia survivors experience negative effects on blood formation decades later

Key molecular pathway for organ damage in COVID patients discovered

SFU researchers study pathogen genes to develop new drugs against bacterial infections

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

IU researchers focus on tackling binge and "high-intensity" drinking

Researchers develop a method for making “mini-heart” using pluripotent stem cells

Scientists secure funding for cutting-edge research on age-related macular degeneration

New anticancer agent activated by ultrasound waves does not have strong side effects

Scientists unearth some of the biological mechanisms behind ferroptosis

Interplay between Western diet, gut microbiota, and cancer development

How does nutrition affect female fertility?

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

New software tool uses genetic data to improve cancer modeling technology

TiY: Cancer diagnosis and treatment in a single step

Newly discovered brain circuit involving the astrocyte may help you to calm down

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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