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First-responder cells launching the repair after heart attack promote inflammation overdrive

First-responder cells launching the repair after a heart attack are so frantic about fixing the damage that they promote more inflammation than necessary, new research in mice suggests.

5 Jan 2022

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

Study uncovers a harmful neutrophil behavior linked to cardiovascular disease

Scientists led by Dr. Andrés Hidalgo at the Centro Nacional de Investigadores Cardiovasculares have discovered that circulating neutrophils - a type of immune cell - acquire different behavior patterns during inflammatory processes.

5 Jan 2022

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

The Wistar Institute announces the initiation of a Phase 2 clinical study of VK-2019 in patients with advanced Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and lymphoma.

5 Jan 2022

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one.

5 Jan 2022

Understanding and overcoming the challenges of chemical synthesis at a global Contract Research Organisation

In this interview, News-Medical talks to Andrew Kennedy and Jono West from Sai Life Sciences, about the work they do and how they utilise Radleys equipment in order to understand and overcome chemical synthesis challenges.

From Radleys 5 Jan 2022

mRNA booster vaccine confers strong protection against SARS-CoV-2 Omicron in cancer patients

A new preprint research paper posted to the medRxiv* server reports the induction of high neutralizing activity in these patients against the Omicron VOC with a booster dose.

5 Jan 2022

Transplant recipients benefit from a COVID-19 vaccine booster

A new preprint research paper posted to the medRxiv* server describes the reduction in humoral immunity in SOTR following vaccination, as well as the improvement with an additional dose of the vaccine.

4 Jan 2022

Prescription drug misuse later in life linked to increased odds of substance use disorder

Nearly half of people in a large U.S. study reported misusing prescription drugs between ages 18-50, which made them more likely to develop substance use disorder symptoms as adults--especially those whose misuse peaked later in life.

4 Jan 2022

New Potocsnak Longevity Institute aims to extend human 'healthspan'

In the not-too-distant future, you'll be able to check into the Human Longevity Laboratory to find out how old you really are, physiologically speaking.

4 Jan 2022

In vitro effect of several antiviral drugs against various SARS-CoV-2 variants of concern

An independent study confirms that current and prospective antiviral treatments are effective in inhibiting severe infection from SARS-CoV-2.

4 Jan 2022

Study finds pan-sarbecovirus nanobodies can enhance development of super-immunity

A new study found that applying pan-sarbecovirus nanobodies shows a strong affinity toward all sarbecovirus clades and neutralized SARS-CoV-2 receptor binding domains

4 Jan 2022

The impact of natural selection on sequence diversity in SARS-CoV-2

Recent genomic analysis demonstrates that the SARS-CoV-2 genome is under two distinct selective forces.

3 Jan 2022

Computational tools reveal how blood enzyme works at the atomic level

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism.

3 Jan 2022

Hypertension-related maternal mortality rates continue to increase in the United States

Chronic hypertension is contributing substantially to maternal deaths in the United States, with particular risk among Black women, according to new research from Rutgers Robert Wood Johnson Medical School's Department of Obstetrics, Gynecology and Reproductive Sciences.

3 Jan 2022

Drugs News and Research

First-responder cells launching the repair after heart attack promote inflammation overdrive

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

Study uncovers a harmful neutrophil behavior linked to cardiovascular disease

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Understanding and overcoming the challenges of chemical synthesis at a global Contract Research Organisation

mRNA booster vaccine confers strong protection against SARS-CoV-2 Omicron in cancer patients

Transplant recipients benefit from a COVID-19 vaccine booster

Prescription drug misuse later in life linked to increased odds of substance use disorder

New Potocsnak Longevity Institute aims to extend human 'healthspan'

In vitro effect of several antiviral drugs against various SARS-CoV-2 variants of concern

Study finds pan-sarbecovirus nanobodies can enhance development of super-immunity

The impact of natural selection on sequence diversity in SARS-CoV-2

Computational tools reveal how blood enzyme works at the atomic level

Hypertension-related maternal mortality rates continue to increase in the United States

Genomic variant may help predict which patients will experience chemotherapy-induced cardiotoxicity

New study shows how cells eat the things around them

Reviewing myocarditis and pericarditis in immunosuppressed individuals following COVID-19 mRNA vaccination

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Once-a-day antiretroviral medicine for children proven to be more effective at suppressing HIV

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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